Search results for " potential"
showing 10 items of 2713 documents
Preparation of Polymeric Nanoparticles by Photo-Crosslinking of an Acryloylated Polyaspartamide in w/o Microemulsion
2004
Biodegradable polymeric nanoparticles have been prepared by UV irradiation of an acryloylated water soluble polymer by an inverse microemulsion. The starting polymer was a α,β‐poly(N‐2‐hydroxyethyl)‐D,L‐aspartamide (PHEA) partially functionalized with glycidyl methacrylate (GMA) in order to introduce reactive vinyl groups in the side chain. The PHEA‐GMA copolymer obtained (PHG) was crosslinked by UV irradiation of the inverse microemulsion prepared by mixing an aqueous solution of PHG with propylene carbonate (PC)/ethyl acetate (EtOAc) in the presence of sorbitan trioleate (SPAN 85) as surfactant. Nanoparticles obtained were characterized by FTIR spectrophotometry, transmission electron mic…
Market potential estimates in history: a survey of methods and an application to Spain, 1867-1930
2014
New Economic Geography (NEG) models stress the importance of access to demand as a key driver of the spatial and temporal distribution of economic activity (Krugman, 1991). Therefore, in order to test the theoretical predictions emanating from NEG a sound measure of accessibility is required. In line with Crafts (2005b), this paper constructs market potential estimates for Spain at the province level (NUTS3) between 1867 and 1930 using Harris’s (1954) equation. This period is particularly appealing as it was during these years that the Spanish market became integrated thanks to the fall in transport and trade costs. A number of key processes, including the substitution of traditional transp…
Testing the Home Market Effects in a Multi-country World: The Theory
2004
We extend the two-country model by Krugman (1980) to a multi-country set-up and show that the `home-market effect' highlighted with two countries does not readily extend to such a more general setting. In particular, we prove that the most important result, namely the disproportionate causation from demand to supply, generalizes only under the fairly implausible assumption of pairwise symmetric trade costs between all countries. We argue, therefore, that the implications of product differentiation for the structure of world trade are better characterized in terms of spatial (`accessibility') and non-spatial (`attraction') effects, and we provide a theory-based specification that suggests ho…
Somatosensory change detection in young healthy twin males
2013
Ensemble deep clustering analysis for time window determination of event-related potentials
2023
Objective Cluster analysis of spatio-temporal event-related potential (ERP) data is a promising tool for exploring the measurement time window of ERPs. However, even after preprocessing, the remaining noise can result in uncertain cluster maps followed by unreliable time windows while clustering via conventional clustering methods. Methods We designed an ensemble deep clustering pipeline to determine a reliable time window for the ERP of interest from temporal concatenated grand average ERP data. The proposed pipeline includes semi-supervised deep clustering methods initialized by consensus clustering and unsupervised deep clustering methods with end-to-end architectures. Ensemble clusterin…
Automatic auditory and somatosensory brain responses in relation to cognitive abilities and physical fitness in older adults
2017
AbstractIn normal ageing, structural and functional changes in the brain lead to an altered processing of sensory stimuli and to changes in cognitive functions. The link between changes in sensory processing and cognition is not well understood, but physical fitness is suggested to be beneficial for both. We recorded event-related potentials to somatosensory and auditory stimuli in a passive change detection paradigm from 81 older and 38 young women and investigated their associations with cognitive performance. In older adults also associations to physical fitness were studied. The somatosensory mismatch response was attenuated in older adults and it associated with executive functions. So…
Koncepcja logistyki klasy światowej w świetle badań
2016
Przedsiębiorstwa stale poszukują sposobów tworzenia przewagi konkurencyjnej. W ostatnich latach można zauważyć rosnące znaczenie logistyki jako systemowej determinanty efektywności i sukcesu przedsiębiorstwa. Logistyka tworzy warunki i możliwości zdobycia i utrzymania trwałej, długofalowej przewagi konkurencyjnej przez przedsiębiorstwa i łańcuchy dostaw. Istotna rola przypisywana jest tzw. logistycznym potencjałom sukcesu przedsiębiorstwa, obejmującym zasoby logistyczne, zdolności logistyczne oraz kompetencje logistyki. Logistyczne potencjały sukcesu przedsiębiorstwa stanowią podstawę szeroko znanej na świecie koncepcji logistyki klasy światowej, opracowanej w Uniwersytecie Stanowym w Michi…
Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3
2005
hCAT-3 (human cationic amino acid transporter type three) was investigated with both the two-electrode voltage clamp method and tracer experiments. Oocytes expressing hCAT-3 displayed less negative membrane potentials and larger voltage-dependent currents than native or water-injected oocytes did. Ion substitution experiments in hCAT-3-expressing oocytes revealed a large conductance for Na + and K + . In the presence of l-Arg, voltage-dependent inward and outward currents were observed. At symmetrical (inside/outside) concentrations of l-Arg, the conductance of the transporter increased monoexponentially with the l-Arg concentrations; the calculated Vmax and KM values amounted to 8.3 AS and…