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showing 10 items of 4213 documents

High Pressure Processing Impact on Alternariol and Aflatoxins of Grape Juice and Fruit Juice-Milk Based Beverages.

2021

High-pressure processing (HPP) has emerged over the last 2 decades as a good alternative to traditional thermal treatment for food safety and shelf-life extension, supplying foods with similar characteristics to those of fresh products. Currently, HPP has also been proposed as a useful tool to reduce food contaminants, such as pesticides and mycotoxins. The aim of the present study is to explore the effect of HPP technology at 600 MPa during 5 min at room temperature on alternariol (AOH) and aflatoxin B1 (AFB1) mycotoxins reduction in different juice models. The effect of HPP has also been compared with a thermal treatment performed at 90 °C during 21 s. For this, different juice models, or…

AflatoxinFood industryFood HandlingLiquid Phase MicroextractionAlternariolPharmaceutical ScienceOrganic chemistryFood Contamination01 natural sciencesArticlealternariolAnalytical ChemistryPascalizationBeverageschemistry.chemical_compoundLactones0404 agricultural biotechnologyQD241-441AflatoxinsTandem Mass Spectrometryjuice modelsDrug Discoverydispersive liquid–liquid microextractionAnimalsVitisFood sciencePhysical and Theoretical ChemistryMycotoxinChromatography High Pressure LiquidOrange juicehigh-pressure processingbusiness.industry010401 analytical chemistry04 agricultural and veterinary sciencesMycotoxinsFood safety040401 food science0104 chemical sciencesFruit and Vegetable JuicesMilkchemistryChemistry (miscellaneous)Fruitaflatoxin B1Molecular Medicinebusinessliquid chromatography coupled to tandem mass spectrometryFood contaminantMolecules (Basel, Switzerland)
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Limited survey for the occurrence of aflatoxins in cereals and poultry feeds from Rabat, Morocco

2007

Fifty eight (58) samples of cereals for human consumption (20 corn flour, 17 wheat flour) and poultry feeds (n=21) purchased from popular markets of Rabat in Morocco were analyzed for aflatoxins (AF) by HPLC with immunoaffinity column (IAC) clean-up and fluorimetric detection. The incidence of AF in corn, wheat flour and poultry feeds was about 80, 17.6 and 66.6% respectively. High contamination levels were found in corn and poultry feeds samples. Levels of contamination of analyzed samples with AFB1 ranged from 0.23 to 11.2, 0.03 to 0.15 and 0.05 to 5.38 ng/g for corn, wheat and poultry feeds respectively. Results showed also that the contamination of 10% of samples of corn was higher than…

AflatoxinWheat flourFood ContaminationBiologyZea maysMicrobiologyToxicologychemistry.chemical_compoundAflatoxinsCorn flourAnimalsFood scienceMycotoxinChromatography High Pressure LiquidPoultry DiseasesTriticumIncidencefood and beveragesGeneral MedicineContaminationAnimal FeedMoroccochemistryEdible GrainChickensFood ScienceInternational Journal of Food Microbiology
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Atrial Fibrillation Is Associated with a Marker of Endothelial Function and Oxidative Stress in Patients with Acute Myocardial Infarction

2015

International audience; Background Atrial fibrillation (AF), whether silent or symptomatic, is a frequent and severe complication of acute myocardial infarction (AMI). Asymmetric dimethylarginine (ADMA), an endogenous eNOS inhibitor, is a risk factor for endothelial dysfunction. We addressed the relationship between ADMA plasma levels and AF occurrence in AMI.Methods 273 patients hospitalized for AMI were included. Continuous electrocardiographic monitoring (CEM) !48 hours was recorded and ADMA was measured by High Performance Liquid Chromatography on admission blood sample.Results The incidence of silent and symptomatic AF was 39(14%) and 29 (11%), respectively. AF patients were markedly o…

Aged 80 and overMalelcsh:RMyocardial Infarctionlcsh:MedicineMiddle AgedArginineRisk Assessment[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemElectrocardiographyOxidative StressLogistic Models[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemRisk FactorsAtrial FibrillationMultivariate AnalysisHumansFemalelcsh:QEndotheliumlcsh:ScienceBiomarkersChromatography High Pressure LiquidResearch ArticleAged
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Target blood pressure in elderly hypertensive patients and in patients with diabetes mellitus

2014

Aged 80 and overmedicine.medical_specialtyPhysiologybusiness.industryDiabetes MellituBlood PressureMiddle Agedmedicine.diseaseBlood pressureInternal medicineDiabetes mellitusHypertensionPractice Guidelines as TopicDiabetes MellitusInternal MedicineHumansMedicineIn patientCardiology and Cardiovascular MedicinebusinessHumanAgedJournal of Hypertension
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Purification and characterisation of a plasmin-sensitive surface protein of Staphylococcus aureus.

1996

Certain methicillin-resistant Staphylococcus aureus strains contain a 230-kDa cell-wall protein which is not present on the surface of other staphylococci. The presence of this 230-kDa protein is associated with a negative test result in commercial assays designed to detect fibrinogen-binding proteins and/or protein A on the staphylococcal surface. We have purified and partially characterised the 230-kDa protein from a lysostaphin digest of a non-agglutinating methicillin-resistant S. aureus strain. Partial amino acid sequence data obtained from the purified protein did not reveal any significant similarities to known proteins which indicates that the protein is novel. The 230-kDa protein w…

AgglutinationStaphylococcus aureusPlasminMolecular Sequence DataCarbohydratesEnzyme-Linked Immunosorbent AssayBiochemistry03 medical and health sciencesAffinity chromatographyBacterial ProteinsCell WallLectinsProtein purificationProtein A/GmedicineTrypsinAmino Acid SequenceFibrinolysinChromatography High Pressure Liquid030304 developmental biology0303 health sciencesMembrane GlycoproteinsbiologySequence Homology Amino Acid030306 microbiologyLysostaphinBinding proteinMolecular biologyPeptide FragmentsMolecular WeightBiochemistrybiology.proteinElectrophoresis Polyacrylamide GelMethicillin ResistanceProtein GProtein Amedicine.drugEuropean journal of biochemistry
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A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice

2010

BACKGROUND: Parkinson's disease (PD), the second most frequent neurodegenerative disorder at old age, can be caused by elevated expression or the A53T missense mutation of the presynaptic protein alpha-synuclein (SNCA). PD is characterized pathologically by the preferential vulnerability of the dopaminergic nigrostriatal projection neurons. METHODOLOGY/PRINCIPAL FINDINGS: Here, we used two mouse lines overexpressing human A53T-SNCA and studied striatal dysfunction in the absence of neurodegeneration to understand early disease mechanisms. To characterize the progression, we employed young adult as well as old mice. Analysis of striatal neurotransmitter content demonstrated that dopamine (DA…

AgingDopaminelcsh:MedicineMicechemistry.chemical_compoundHomer Scaffolding ProteinsReceptor Cannabinoid CB1lcsh:ScienceLong-term depressionNeurotransmitterChromatography High Pressure LiquidIn Situ Hybridization FluorescenceOligonucleotide Array Sequence AnalysisMice KnockoutNeuronal PlasticityMultidisciplinaryReverse Transcriptase Polymerase Chain ReactionDopaminergicNeurodegenerationGenetics and Genomics/Gene ExpressionElectrophysiologyalpha-SynucleinResearch ArticleRadioimmunoprecipitation Assaymedicine.medical_specialtyNeuronal Calcium-Sensor ProteinsHOMER1Substantia nigraNeurotransmissionBiologyNeurological DisordersInternal medicinemedicineAnimalsHumansddc:610Cyclic Nucleotide Phosphodiesterases Type 7Activating Transcription Factor 2lcsh:RNeuropeptidesmedicine.diseaseMolecular biologyCorpus StriatumMice Mutant StrainsEndocrinologyGenetics and Genomics/Disease ModelschemistrySynaptic plasticitylcsh:QCarrier ProteinsPLoS ONE
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The involvement of ankle muscles in maintaining balance in the upright posture is higher in elderly fallers

2016

International audience; The purpose of this study was to determine whether the mechanical contribution of ankle muscles in the upright stance differed among young adults (YA) (n = 10, age: similar to 24.3), elderly non-fallers (ENF) (n = 12, age: similar to 77.3) and elderly fallers (EF) (n = 20, age: similar to 80.7). Torque and electromyographic (EMG) activity were recorded on the triceps surae and tibialis anterior during maximum and submaximum contractions in the seated position. EMG activity was also recorded in subjects standing still. Plantar flexor (PF) and dorsal flexor (DF) torques generated in the upright posture were estimated from the torque-EMG relationship obtained during sub…

AgingPoison controltorqueBiochemistryPlantar flexionAnkle muscles0302 clinical medicineEndocrinologyCenter of pressure (terrestrial locomotion)jointFallMedicineolder-adultsPostural BalanceriskAged 80 and overMuscle Weaknessswaymedicine.anatomical_structurePostural stabilitymedicine.symptomDorsumBalancemedicine.medical_specialtyIsometric torque[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyYoung Adult03 medical and health sciencesPhysical medicine and rehabilitationGeneticsHumansskeletal-muscleMuscle SkeletalMolecular BiologyAgedsoleusElectromyographybusiness.industryyoungMuscle weakness030229 sport sciencesCell BiologyIsometric torquebody regionsagePhysical therapyAccidental FallsfatigueAnklebusinessAnkle Joint030217 neurology & neurosurgery
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Electrocardiographic and other clinical correlates of walking ability in older women

2009

Abstract The purpose of this study was to examine how resting electrocardiographic (ECG) and other clinical variables, which can be included in a routine clinical examination, predict walking ability in older women. Three hundred and twenty women (63–75 years) without overt cardiac diseases and apparent mobility limitations were studied. Measurements performed were clinical examination (standard 12-lead resting ECG, assessment of physical activity level, presence of chronic diseases, use of beta-blockers, body mass index (BMI), ability to squat, resting blood pressure) and six-minute walking test. Participants walked 533 ± 75 m in the six-minute walking test. The best electrocardiographic p…

Agingmedicine.medical_specialtyHealth (social science)Adrenergic beta-AntagonistsBlood PressurePhysical examinationSquatWalking030204 cardiovascular system & hematologyLeft ventricular hypertrophyBody Mass IndexElectrocardiography03 medical and health sciencesWalking distance0302 clinical medicinemedicineHumans030212 general & internal medicineMobility LimitationAged2. Zero hungermedicine.diagnostic_testWalking testbusiness.industryMiddle Agedmedicine.diseasePhysical activity level3. Good healthBlood pressurePhysical FitnessHypertensionExercise TestPhysical therapyFemaleGeriatrics and Gerontologybusinesshuman activitiesGerontologyBody mass indexArchives of Gerontology and Geriatrics
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Postural balance and health-related factors in middle-aged and older women with injurious falls and non-fallers.

2004

Background and aims: Older jailers aged over 70 years have shown impaired balance abilities, but it is unclear if impairment in balance control can be detected among jallers who are in their 50’s and 60’s. The aim oj this study was to analyze possible differences in balance control and other health-related factors between female fallers and nonfallers aged 50–68 years. Methods: Women 50–68 years of age (N=40) who had fallen outside and needed medical attention were recruited through a larger fall accident study. Non-fallers (N=97) were women representing the same age group who had not fallen during the preceding 12 months. A battery of standing force platform balance tests were administered…

Agingmedicine.medical_specialtyHormone Replacement TherapyHealth StatusMovementStatistics as TopicPoison controlBlood PressureSuicide preventionDizzinessOccupational safety and healthInterviews as TopicRisk FactorsInjury preventionmedicinePostural BalanceHumansForce platformBody Weights and MeasuresHearing LossPostural BalanceFinlandVision OcularBalance (ability)AgedImpaired Balancebusiness.industryAge FactorsMiddle AgedChronic DiseasePhysical therapyAccidental FallsFemaleGeriatrics and GerontologybusinessVisually Impaired PersonsAging clinical and experimental research
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Cardiac Micro–Computed Tomography Imaging of the Aging Coronary Vasculature

2012

Background— Alterations at the level of the coronary circulation with aging may play an important role in the evolution of age-associated changes in left ventricular (LV) fibrosis and function. However these age-associated changes in the coronary vasculature remain poorly defined primarily due to the lack of high resolution imaging technologies. The current study was designed to utilize cardiac micro–computed tomography (micro-CT) technology as a novel imaging strategy, to define the 3-dimensional coronary circulation in the young and aged heart and its relationship to LV fibrosis and function. Methods and Results— Young (2 months old; n=10) and aged (20 months old; n=10) Fischer rats unde…

Agingmedicine.medical_specialtyX-ray microtomographyBlood PressureArticleVentricular Dysfunction LeftCoronary circulationImaging Three-DimensionalFibrosisCoronary CirculationInternal medicineLv dysfunctionAnimalsMedicineRadiology Nuclear Medicine and imagingbusiness.industryMicro computed tomographyCoronary vasculatureImaging studyX-Ray Microtomographymedicine.diseaseFibrosisSettore MED/11 - Malattie Dell'Apparato CardiovascolareRats Inbred F344Ratsmedicine.anatomical_structureBlood pressureEchocardiographyHigh resolution imaging techinques.Linear ModelsCardiologyCardiology and Cardiovascular MedicinebusinessCirculation: Cardiovascular Imaging
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