Search results for " press"

Safety and feasibility of atropine added in patients with sub-maximal heart rate during exercise myocardial perfusion SPECT.

2006

Failure to reach 80% of maximal predicted heart rate (HR) during exercise may render a myocardial perfusion single photon emission computed tomography (SPECT) study non-diagnostic for ischemia detection. We sought to investigate the injection of atropine in patients who fail to achieve 80% of age-predicted HR during exercise performed for myocardial perfusion SPECT (MPS), defining its safety and efficacy to raise HR to adequate levels as well as its effect on MPS interpretation.Between January 2002 and December 2004, we studied 3,150 consecutive patients (2,253 men and 897 women, mean age 55 +/- 6 years) who were referred to a single office-based nuclear cardiology laboratory for MPS using …

Storage and release of false transmitters after infusion of (+)- and (?)-?-methyldopamine

1971

Rabbits were given an infusion of 10 mg/kg (−)- or 30 mg/kg (+)-α-methyldopamine and killed after 135 min. The noradrenaline content of the heart was decreased to 26±5 and 34±2%, respectively, of the control value. After infusion of the (+)-isomer the missing noradrenaline was replaced by (−)-α-methylnoradrenaline. Electrical stimulation of the sympathetic nerves or infusion of acetylcholine plus atropine caused an output of noradrenaline and (−)-α-methylnoradrenaline from the isolated heart. The two amines were released in the same proportion as they were stored in the heart and the total output of both amines equalled the output of noradrenaline from control hearts. Nerve stimulation caus…

The non-neuronal cholinergic system in peripheral blood cells: Effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory …

2007

Peripheral blood cells express the complete non-neuronal cholinergic system. For example synthesis of acetylcholine and nicotinic as well muscarinic receptors have been demonstrated in leucocytes isolated from human peripheral blood. In the present experiments mononuclear cells and granulocytes were isolated from the peripheral blood to investigate content and synthesis of acetylcholine as well as phenotypic functions like respiratory burst, phagocytosis and migration. Mononuclear cells (T-cells and monocytes) contained 0.36 pmol/10(6) cells acetylcholine, whereas acetylcholine content in granulocytes was 100-fold lower. Acetylcholine synthesis amounted to 23.2+/-4.7 nmol/mg protein/h and 2…

2013

To identify factors limiting performance in multitone intensity discrimination, we presented sequences of five pure tones alternating in level between loud (85 dB SPL) and soft (30, 55, or 80 dB SPL). In the “overall-intensity task”, listeners detected a level increment on all of the five tones. In the “masking task”, the level increment was imposed only on the soft tones, rendering the soft tones targets and loud tones task-irrelevant maskers. Decision weights quantifying the importance of the five tone levels for the decision were estimated using methods of molecular psychophysics. Compatible with previous studies, listeners placed higher weights on the loud tones than on the soft tones i…

A Mechano-Chemical Coupling for Hydrogen Diffusion in Metals Based on a Thermodynamic Approach

2014

Hydrogen diffusion in metals is still an ongoing topic of research due to its technical relevance (hydrogen embrittlement, hydrogen storage...). In the last decades, significant progress in understanding the time evolution of the hydrogen concentration in solids was completed. This paper presents a modeling of hydrogen diffusion with a general and thermodynamically based diffusion concept coupled with mechanical and chemical aspects. This model was previously used to simulate the oxidation of a metal [1][2]. This concept has been upgraded to offer a thoroughly macroscopic behavior law used to simulate hydrogen diffusion in metal parts under mechanical loadings. The thermodynamic approach of…

Protease A activity and nitrogen fractions released during alcoholic fermentation and autolysis in enological conditions

2000

Determination of protease A activity during alcoholic fermentation of a synthetic must (pH 3.5 at 25 degrees C) and during autolysis showed that a sixfold induction of protease A activity occurred after sugar exhaustion, well before 100% cell death occurred. A decrease in protease A activity was observed when yeast cell autolysis started. Extracellular protease A activity was detected late in the autolysis process, which suggests that protease A is not easily released. Evolution of amino acids and peptides was determined during alcoholic fermentation and during autolysis. Amino acids were released in early stationary phase. These amino acids were subsequently assimilated during the fermenta…

Sleep Apnea, Sleepiness, and Driving Risk

2019

Obstructive sleep apnea is associated with excessive daytime sleepiness in about 50% of cases, and with increased risk of driving accidents. Treatment with continuous positive airway pressure effectively decreases such risk, but compliance with continuous positive airway pressure treatment is often suboptimal. According to the European Union Directive on driving risk, retention of a driving license in patients with obstructive sleep apnea requires assessment of sleepiness and adherence to continuous positive airway pressure treatment, but there remains uncertainty on the optimal methods to assess sleepiness on a large scale.

DETERMINATION OF TDC IN INTERNAL COMBUSTION ENGINES BY A NEWLY DEVELOPED THERMODYNAMIC APPROACH

2010

Abstract In-cylinder pressure analysis is nowadays an indispensable tool in internal combustion engine research & development. It allows the measure of some important performance related parameters, such as indicated mean effective pressure (IMEP), mean friction pressure, indicated fuel consumption, heat release rate, mass fraction burned, etc. Moreover, future automotive engine will probably be equipped with in-cylinder pressure sensors for continuous combustion monitoring and control, in order to fulfil the more and more strict emission limits. For these reasons, in-cylinder pressure analysis must be carried out with maximum accuracy, in order to minimize the effects of its characteristic…

Response to Cardiovascular Autonomic Dysfunction as a Link Between Insulin Resistance and Nocturnal Blood Pressure Elevation

2008

We welcome the interest that Perciaccante1 has shown in our research on the impact of obesity and insulin resistance in nocturnal blood pressure elevation in children and adolescents.2 We agree with his hypothesis that abnormal cardiovascular autonomic function is a potential link between insulin resistance …

Testing a Simplified Approach to Determine Field Saturated Soil Hydraulic Conductivity

2013

Abstract Interpreting and simulating hydrological processes need a large number of field saturated soil hydraulic conductivity, Kfs , data that should be collected with simple and rapid field experiments. A Simplified method based on a Beerkan Infiltration run (SBI method) was recently developed and tested successfully on Burundian soils. With the SBI method, a cylinder is inserted to a short depth into the soil and the infiltration time of a few small volumes of water repeatedly applied at the surface of the confined soil is measured. Calculating Kfs needs the slope of the linearized cumulative infiltration vs. time relationship and an estimate of the so called α* parameter. In this invest…