Search results for " priority"

showing 10 items of 71 documents

Association between osteocalcin and cognitive performance in healthy older adults.

2016

INTRODUCTION: cognitive deterioration and reductions of bone health coincide with increasing age. We examine the relationship between bone composition and plasma markers of bone remodelling with measures of cognitive performance in healthy adults.METHODS: this cross-sectional study included 225 old (52% women, mean age: 74.4 ± 3.3 years) and 134 young (52% women, mean age: 23.4 ± 2.7 years) adult participants from the MyoAge project. Whole body bone mineral density was measured by dual-energy X-ray absorptiometry. Blood analyses included a panel of bone-related peptides (dickkopf-1, osteoprotegerin, osteocalcin (OC), osteopontin, sclerostin, parathyroid hormone and fibroblast growth factor …

cognitionMaleAgingosteopontinvery elderlyCognitive declinesclerostinNeuropsychological Testsolder peopleExecutive FunctionAbsorptiometry PhotonBone Densityblood analysiscognitive defectphoton absorptiometry80 and overcalcium blood leveldickkopf 1 protein25 hydroxyvitamin D; calcium; dickkopf 1 protein; fibroblast growth factor 23; osteocalcin; osteopontin; osteoprotegerin; parathyroid hormone; sclerostin; biological marker; osteocalcin adult; aged; Article; blood analysis; bone density; bone remodeling; calcium blood level; cognition; controlled study; cross-sectional study; dual energy X ray absorptiometry; episodic memory; executive function; female; human; male; neuropsychological test; priority journal; working memory; adolescent; age; aging; blood; clinical trial; cognitive aging; cognitive defect; comparative study; Europe; metabolic bone disease; multicenter study; photon absorptiometry; psychology; sex difference; short term memory; very elderly; young adult Absorptiometry Photon; Adolescent; Adult; Age Factors; Aged; Aged 80 and over; Aging; Biomarkers; Bone Density; Bone Diseases Metabolic; Bone Remodeling; Cognition; Cognition Disorders; Cognitive Aging; Cross-Sectional Studies; Europe; Executive Function; Female; Humans; Male; Memory Episodic; Memory Short-Term; Neuropsychological Tests; Osteocalcin; Sex Factors; Young Adult; Ageing; Cognitive decline; Older people; Osteocalcincomparative studyAged 80 and overdual energy X ray absorptiometryadultAge Factorsclinical trialepisodic memorybiological markerPhotonEuropeagedMemory Short-Termfemalepriority journalyoung adultmetabolic bone diseaseBone RemodelingBone DiseasesEpisodicResearch PaperAdolescentMemory Episodicsex differenceOsteocalcinosteocalcinpsychologyArticleworking memoryfibroblast growth factor 23short term memorySex FactorsbloodMemoryparathyroid hormonecross-sectional studyHumanscontrolled studyhumanAbsorptiometrycalciumcognitive agingcognitive declineBone Diseases MetabolicAgeingikääntyminen25 hydroxyvitamin Dmulticenter studyCross-Sectional StudiesageShort-Termosteoprotegerinneuropsychological testMetabolicOlder peopleCognition DisordersBiomarkers
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Increased conformational rigidity of humic substances by oxidative biomimetic catalysis

2005

A synthetic water-soluble meso-tetra(2,6-dichloro-3-sulfonatophenyl)porphyrinate of iron(III) chloride, Fe(TDCPPS)Cl, was employed as a biomimetic catalyst in the oxidative coupling of terrestrial humic materials. High-performance size-exclusion chromatography (HPSEC), solid-state nuclear magnetic resonance (CPMAS-(13)C NMR), electron paramagnetic resonance (EPR), and diffuse reflectance infrared spectroscopy (DRIFT) were used to follow conformational and structural changes brought about in different humic materials by the oxidative coupling. Increase in apparent weight-average molecular weight (Mw(a)) occurred invariably for all humic substances with the oxidative polymerization catalyzed …

conformationMagnetic Resonance SpectroscopySpectrophotometry InfraredPolymers and PlasticsDiffuse reflectance infrared spectroscopy (DRIFT)Biomimetic materialsaromatic compoundgel permeation chromatographyMolecular ConformationPhotochemistryIron compoundslaw.inventionPolymerizationenvironmental managementcovalent bondlawSize exclusion chromatographyBiomimetic catalysisBiomimeticsMaterials ChemistryOrganic chemistryHumic acidElectron paramagnetic resonanceInfrared spectroscopyChromatography High Pressure Liquidchemistry.chemical_classificationSettore CHIM/03 - Chimica Generale e InorganicaCarbon IsotopesChromatographyindustryCatalystsChemistrytetra(2articleelectrophoretic mobilitybiomimetic materialNuclear magnetic resonance spectroscopyunclassified drugConformationsacetic acidpriority journalCovalent bondSpectrophotometrySynthesis (chemical)High Pressure Liquidtechnology6 dichloro 3 sulfonatophenyl)porphyrinic acid derivativeInfraredOxidation-Reductionmolecular stabilityHumic materialsoxidationSettore AGR/13 - Chimica AgrariaSupramolecular chemistryBioengineeringcomplex mixturesCatalysisCatalysisdiffuse reflectance spectroscopyhumic substanceBiomaterialsalkyl etherElectron spin resonance spectroscopycomplex formationParticle SizeNuclear magnetic resonance spectroscopyHumic Substancesfree radicalbiomimetic oxidative humicelectron spin resonanceHigh performance size exclusion chromatography (HPSEC)ferrous chloridemolecular weightsolid statecarbon nuclear magnetic resonancePolymerizationSolubilitychemical structureOxidative coupling of methaneCatalysts; Conformations; Electron spin resonance spectroscopy; Infrared spectroscopy; Iron compounds; Nuclear magnetic resonance spectroscopy; Oxidation; Polymerization; Size exclusion chromatography; Solubility; Synthesis (chemical); Biomimetic catalysis; Diffuse reflectance infrared spectroscopy (DRIFT); High performance size exclusion chromatography (HPSEC); Humic materials; Biomimetic materials; acetic acid; alkyl ether; aromatic compound; biomimetic material; ferrous chloride; free radical; tetra(26 dichloro 3 sulfonatophenyl)porphyrinic acid derivative; unclassified drug; article; carbon nuclear magnetic resonance; catalysis; catalyst; chemical structure; complex formation; conformation; covalent bond; diffuse reflectance spectroscopy; electron spin resonance; electrophoretic mobility; environmental management; gel permeation chromatography; humic substance; industry; molecular stability; molecular weight; oxidation; polymerization; priority journal; solid state; technology; Biomimetics; Carbon Isotopes; Catalysis; Chromatography High Pressure Liquid; Electron Spin Resonance Spectroscopy; Humic Substances; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxidation-Reduction; Particle Size; Spectrophotometry Infraredcatalyst
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The RIBES strategy for ex situ conservation: conventional and modern techniques for seed conservation

2022

The Italian seed bank network (RIBES) aims to improve the quality and safety of the germplasm reserves of native plant species in Italy to ensure the long-term conservation of endangered and/or endemic flora. The strategy includes traditional methods to secure seed conservation. A comprehensive priority list for seed collection is being defined, it was prepared by crossing data of various checklists (red lists, endemics) and will soon be cross-referenced with an updated list of accessions of the whole network. A safety-backup program of duplicates will quickly be implemented to secure the conservation of the most threatened species in at least two seed banks of the network. On the other han…

conservation strategyseed/spore researchSettore BIO/02 - Botanica SistematicaSettore BIO/03 - Botanica Ambientale E ApplicataItalian floraPlant Sciencepriority listsseed banksconservation strategy; Italian flora; priority lists; seed banks; seed/spore research
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Histologic analysis of specimens from laparoscopic endometrioma excision performed by different surgeons: does the surgeon matter?

2011

Objective To evaluate whether the amount of ovarian tissue inadvertently removed along with the endometrioma cyst wall at laparoscopy differs in relation to the operating surgeon's level of expertise. Design Multicenter, prospective trial. Setting Four tertiary care university hospitals. Patient(s) Fifty patients, aged 25 to 40 years, with monolateral ovarian endometriomas who underwent laparoscopic excision. Intervention(s) Operation with the stripping technique by surgeons with specific expertise in endometriosis surgery in four centers (groups A, B, C, and D) and by residents with average training in laparoscopic surgery (group E). Main Outcome Measure(s) Histologic examination for the e…

endometriosisLaparoscopic surgerymedicine.medical_treatmentEndometriosisEndometriosis laparoscopy ovarian cystsGynecologic Surgical Proceduresmorphologyovarian endometriomaMedicineSingle-Blind MethodOvarian DiseasesLaparoscopyclinical articleresidency educationmedicine.diagnostic_testmedical specialistarticleObstetrics and Gynecologyendometriosis; laparoscopy; ovarian cystsOrgan Sizelaparoscopic surgeryTumor Burdenendometrium tumorfemaleuterus surgerymedicine.anatomical_structurepriority journalstripping techniquehistopathologyClinical CompetenceAdultmedicine.medical_specialtyOvaryPhysiciansHumanshumanOvarian cystbusiness.industryOvaryHistologymedicine.diseasehuman tissuethicknessSurgeryEndoscopyadult; article; clinical article; endometriosis; endometrium tumor; female; histopathology; human; human tissue; laparoscopic surgery; medical specialist; morphology; multicenter study; ovarian endometrioma; ovary; priority journal; residency education; stripping technique; surgeon; thickness; uterus surgery Adult; Clinical Competence; Endometriosis; Female; Gynecologic Surgical Procedures; Humans; Laparoscopy; Organ Size; Ovarian Diseases; Ovary; Physicians; Single-Blind Method; Tumor Burdenmulticenter studySettore MED/40 - GINECOLOGIA E OSTETRICIAReproductive MedicinesurgeonLaparoscopyHistopathologybusiness
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One-pot synthesis of fluorinated 2-amino-pyrimidine-N-oxides. Competing pathways in the four-atom side-chain rearrangements of 1,2,4-oxadiazoles

2006

Abstract Trifluoromethylated 2-amino-pyrimidine N-oxides have been synthesized by reaction of the 3-amino-5-methyl-1,2,4-oxadiazole with trifluoromethyl-β-diketones in the presence of perchloric acid, followed by hydrolysis. In this ring-to-ring transformation an initial formation of (unisolated) 1,2,4-oxadiazole-pyrimidinium salts, and subsequent ring-opening at the oxadiazole moiety occurs. Isolation of 2-(hydroxyamino)-pyrimidine from the reaction mixture evidenced the presence of a competing pathway where the N(4) nitrogen of the oxadiazole is involved in the formation of a regioisomeric pyrimidinium salt. The effect of the trifluoromethyl group on the product distribution is discussed.…

fluoropyrimidine derivativecrystal structurepyrimidine N-oxidePyrimidinesynthesisStereochemistryOne-pot synthesisOxadiazoleX ray analysis3 diketoneBiochemistryMedicinal chemistryperchloric acidnitrogenchemistry.chemical_compoundside-chain rearrangementDrug DiscoveryStructural isomerSide chainMoietyPerchloric acidring openingfluorinated heterocycle3 diketone fluoropyrimidine derivative ketone derivative nitrogen oxide perchloric acid; article crystal structure hydrolysis priority journal reaction analysis ring opening synthesis X ray analysisTrifluoromethylChemistryOrganic Chemistryarticle124-oxadiazoleketone derivativereaction analysishydrolysispriority journaloxide
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Observation of the rare B(s)(0) + decay from the combined analysis of CMS and LHCb data.

2015

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported licence.-- et al.

fundamental particleCompact Muon Solenoidstandard model flavor changing neutral currentsradioisotope decayB physicGaussian methodMU(+)MU(-)Temel Bilimler (SCI)rare decay [B/s0]Elementary particleATLAS DETECTOR12.15.MmÇOK DİSİPLİNLİ BİLİMLERRARE B-MESON DECAYS7000 GeV-cms8000 GeV-cmsSettore ING-INF/01 - Elettronica01 natural sciences7. Clean energyddc:0702 CHARGED LEPTONSscattering [p p]High energy physics ; Experimental particle physics ; LHC ; CMS ; Standard ModelQC[Anahtar Kelime Yok]Large Hadron ColliderMedicine (all); Multidisciplinarystandard3. Good healthHigh Energy Physics - PhenomenologyCERN LHC CollFIS/01 - FISICA SPERIMENTALEpriority journalHiggs bosonScience & Technology - Other TopicsPARTICLE PHYSICSmass spectrum [dimuon]Protonviolationcolliding beams [p p]physicschemical analyzerMesonModels beyond the standard modelprobabilitymesonelectromagnetic radiationB/s0 --> muon+ muon-Nuclear physicsbranching ratio: measured [B0]SEARCHLeptonic semileptonic and radiative decays of bottom mesonRARE B-MESON DECAYS; MINIMAL FLAVOR VIOLATION; LHC; CMS DETECTOR; LHCb DETECTOR; SEARCH; MU(+)MU(-); B-S(0); B-0;B-MESON DECAYS; MINIMAL FLAVOR VIOLATION; 2 CHARGED LEPTONS; ATLAS; DETECTOR; SEARCH; MU(+)MU(-); B-S(0); B-0; COLLIDER; PARTICLE010306 general physicsScience & TechnologyMuonMULTIDISCIPLINARY SCIENCES010308 nuclear & particles physicsBranching fractionMeson Bnull hypothesisDoğa Bilimleri GenelElementary particlesLARGE HADRON COLLIDERHEPp(p)over-bar collisionsNATURAL SCIENCES GENERALrare decay [B0]13.20.HeMINIMAL FLAVOR VIOLATIONchemical analysisprecisionB0 --> muon+ muon-Física de partículesExperimental particle physicsleptonic decay [B0]Physics::Instrumentation and DetectorsPhysics beyond the Standard ModelB-meson decays; p(p)over-bar collisions; branching fraction; root-s=1.96 tev; search; mu(+)mu(-); b-0; b-s(0); violation; modelsLarge Hadron Collider (LHC)High Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNeutral currentCOLLIDER[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]uncertainty12.60.-iFlavour Physicmass spectrometryPhysicsExperimental particleMultidisciplinaryCMSMedicine (all)Temel BilimlerSettore FIS/01 - Fisica SperimentaleB-meson decaysATLASLarge Hadron Collider beautybranching ratio: measured [B/s0]root-s=1.96 tevNatural Sciences (SCI)LHCNatural SciencesPARTICLEdata processingParticle Physics - Experimentchemical reactionParticle physicsbranching fractionNOPARTICLE PHYSICS; LARGE HADRON COLLIDER; CMS; LHCBmodelsLHCBExperimental particle; physics; data processing; electromagnetic field; electromagnetic radiation; fundamental particle; Gaussian method; physics; precision; chemical analysis; chemical analyzer; chemical reaction; elementary particle; Large Hadron Collider beauty; mass spectrometry; meson; null hypothesis; prediction; priority journal; probability; radioisotope decay; standard; uncertainty;B-MESON DECAYSelectromagnetic fieldTheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITYRare Decay0103 physical sciencesElectromagnetic fieldB-0elementary particleSDG 7 - Affordable and Clean EnergyDETECTORCompact Muon SolenoidMultidisipliner/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyLHCb DETECTORCMS LHC Meson B Rare DecayMinimal flavor violationpredictionLeptonsLHC-Bleptonic decay [B/s0]LHCbRare decayMedicine (all) MultidisciplinaryRARE B-MESON DECAYS; MINIMAL FLAVOR VIOLATION; LHC; CMS DETECTOR; LHCb DETECTOR; SEARCH; MU(+)MU(-); B-S(0); B-0B-S(0)[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]High Energy Physics::ExperimentExperimentsexperimental resultsCMS DETECTOR
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Partio kasvattajana

2013

Mäkinen, S. 2013. Partio kasvattajana. Kasvatustieteen pro gradu –tutkielma. Opettajankoulutuslaitos. Jyväskylän yliopisto. Tutkimuksen tavoitteena oli selvittää, onko partiotoiminnalla suotuisa vaikutus peruskoulun oppimistavoitteiden saavuttamiseen. Partion ja peruskoulun tavoitteet ovat samansuuntaiset ja osin jopa yhtenevät, joten hypoteesina oli, että partiolaiset asennoituvat tilastollisesti merkitsevästi enemmän peruskoulun kasvatustavoitteiden suuntaisesti kuin vertailuryhmänä olleet peruskoululaiset, jotka eivät ole missään varhaisnuorisotoiminnassa mukana. Tuloksia käsiteltiin faktorianalyysillä. Saatuja faktoripisteitä vertailtiin t-testillä. Partiolaisten asenteissa oli vain väh…

partioeducational prioritymoraaliattitudeasenteetasennekasvatustavoitteetscouting
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“Relative priority rule” e diritti dei soci nel concordato preventivo in continuità

2022

La codificazione di nuove regole di possibile distribuzione del valore ritraibile dall’impresa in crisi oggetto di ristrutturazione fra i creditori – e non solo fra questi, venendo ora in gioco anche una nuova disciplina delle possibili attribuzioni ai soci – è una delle più rilevanti innovazioni introdotte con l’entrata in vigore del Codice della crisi di impresa e di insolvenza, come novellato dal d.gs. 17 giugno 2022, n. 83, in attuazione della Direttiva (UE) 2019/1023. Il lavoro ripercorre la genesi e lo sviluppo di tali regole nell’orizzonte statunitense e poi in quello europeo, per poi tornare alla recente disciplina italiana in esame, con particolare attenzione al trattamento dei soc…

relative absolute priority rule concordato preventivo continuità attribuzioni soci societàSettore IUS/04 - Diritto Commercialerelative priority rule surplus going concern
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FMECA Application in Tomotherapy: Comparison between Classic and Fuzzy Methodologies

2022

Accident analysis in radiotherapy highlighted the need to increase quality assurance (QA) programs by the identification of failures/errors with very low probability (rare event) but very severe consequences. In this field, a Failure Mode, Effects and Criticality Analysis (FMECA) technique, used in various industrial processes to rank critical events, has been met with much interest. The literature describes different FMECA methods; however, it is necessary to understand if these tools are incisive and effective in the healthcare sector. In this work, comparisons of FMECA methodologies in the risk assessment of patients undergoing treatments performed with helical tomotherapy are reported. …

risk assessment; FMEA; FMECA; radiotherapy; health physics; fuzzy risk priority numberRenewable Energy Sustainability and the Environmentfuzzy risk priority numberEcology Evolution Behavior and SystematicsFMEAradiotherapySettore ING-IND/19 - Impianti NucleariGeneral Environmental ScienceRisk assessmentFMECAhealth physics
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TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma

2005

To prospectively evaluate the prognostic significance of TP53, H-, K-, and N-Ras mutations, DNA-ploidy and S-phase fraction (SPF) in patients affected by locally advanced laryngeal squamous cell carcinoma (LSCC). Eight-one patients (median follow-up was 71 months) who underwent resective surgery for primary operable locally advanced LSCC were analyzed. Tumor DNA was screened for mutational analysis by PCR/SSCP and sequencing. DNA-ploidy and SPF were performed by flow cytometric analyses. Thirty-six patients (44%) had, at least, a mutation in the TP53 gene. Of them, 22% (8/36) had double mutations and 3% (1/36) had triple mutations. In total, 46 TP53 mutations were observed. The majority (41…

squamous cell carcinomasingle strand conformation polymorphismPrognosipolymerase chain reactionDNA Mutational AnalysisEMTREE drug terms: protein p53 EMTREE medical terms: advanced cancerS PhaseDNA Mutational AnalysiHumansprotein p53 advanced cancer; article; cell cycle S phase; DNA content; exon; flow cytometry; follow up; gene; gene mutation; genetic analysis; histopathology; human; human tissue; larynx carcinoma; multivariate analysis; ploidy; polymerase chain reaction; priority journal; prospective study; single strand conformation polymorphism; squamous cell carcinoma; tp53 gene Carcinoma Squamous Cell; DNA Mutational Analysis; DNA Neoplasm; Genes ras; Humans; Laryngeal Neoplasms; Mutation; Ploidies; Polymorphism Single-Stranded Conformational; Prognosis; S Phase; Survival Rate; Tumor Suppressor Protein p53 [EMTREE drug terms]follow uplarynx carcinomatp53 gene MeSH: Carcinoma Squamous Cellexongene mutationhumanmultivariate analysigeneLaryngeal NeoplasmsPolymorphism Single-Stranded ConformationalLaryngeal NeoplasmPloidiesflow cytometryarticleploidyDNA NeoplasmPrognosisGenes rahuman tissueSurvival RateGenes rascell cycle S phasepriority journalDNA contentgenetic analysiMutationCarcinoma Squamous CellhistopathologyTumor Suppressor Protein p53Ploidieprospective study
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