Search results for " protect"
showing 10 items of 1247 documents
La teneur hépatique en F4-Neuroprostanes : une variable prédictive majeure de la réduction de la plaque d’athérome
2012
Le fichier annexe contient le livre des résumés; Les propriétés athéroprotectrices des acides gras polyinsaturés de type n-3 à longue chaîne (AGPI n-3 LC), et en particulier de l’acide docosahexaénoique (DHA) ont été largement décrites. Néanmoins, les mécanismes d’action restent encore mal connus. Les recherches se sont récemment orientées vers l’identification des métabolites oxygénés issus des AGPI n-3 LC qui sont de plus en plus considérés comme des effecteurs majeurs de leurs effets athéroprotecteurs. Dans ce contexte, une étude dose-réponse de supplémentation en DHA a été réalisée chez un modèle animal d’athérosclérose (souris LDLR-/-) afin d’étudier les relations entre la progression …
Fatty Acid Smell, Anesthesia, and Use on Fruit Crops
2023
Odors convey important information to select a sex partner, to find a food source, or to detect a danger. Among those some volatile molecules have been shown to cause a reversible anesthesia. However, their mode of action appears still largely mysterious. Here we describe a novel property of Olfactory Receptor 47b (OR47b), on olfactory sensory neurons (OSNs) expressing male-specific transcription factor FruM. We found some interesting properties of a fatty acid that can be present on food sources and oviposition sites for Drosophilid species. We show that OR47b neurons projecting to VA1v glomerulus are sensitive to this odor, and that this influences Drosophila behavior causing a strong ave…
The Crosstalk of Adipose-Derived Stem Cells (ADSC), Oxidative Stress, and Inflammation in Protective and Adaptive Responses
2020
International audience; The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared with other sources, adipose-derived stem cells (ADSCs) have the advantage of being abundant and easy to obtain. ADSCs are considered to be tools for replacing, repairing, and regenerating dead or damaged cells. The capacity of ADSCs to maintain their properties depends on the balance of complex signals in their microenvironment. Their properties and the associated outcomes are in part regulated by reactive oxygen species, which medi…
Some Plant Defense Stimulators can induce IL-1β production in human immune cells in vitro
2020
8 pages; International audience; Among Plant Protection Products (PPP), a new emerging category of pesticides act by stimulating plant defense in order to improve plant resistance against microbial pathogens. Given that these compounds, the so-called Plant Defense Stimulators (PDS) act on innate immunity, we tested, using an in vitro approach on human mononuclear leucocytes (PBMC), the potential toxicity (XTT assay) and inflammatory effects (production of IL-1β) of 4 PPP belonging to different chemical families. We found that two products (LBG-01F34® and Regalis®) did not induce any cytotoxicity or IL-1 β production. The product BION-50 WG®, that contains Acibenzolar-S-methyl (ASM) and sili…
Study of virus flows between wild and cultivated Poaceae
2017
BGPI : équipe 6; Study of virus flows between wild and cultivated Poaceae. 16. Rencontres de Virologie Végétale (RVV 2017)
Biodiversité fongique du raisin au vin : impact de l'activité anthropique
2016
The effects of different anthropogenic activities (vineyard, winery) on fungal populations from grape to wine were studied. To characterize these effects, it was necessary to access to the overall diversity of populations (pyrosequencing and spectroscopy FT-IR) but also to intra-specific diversity (FT-IR). Spectroscopy FT-IR has been validated for their ability to characterize the global population and to discriminate the strains for three species of non-Saccharomyces yeasts (NS). For the first time, it is shown that the grape berry is a limited source for NS yeasts while the winery seems to be a significant source; the air is an important vector for dissemination of these yeasts. In additi…
Role of the non-infective stage of the acanthocephalan parasite Pomphorhychus laevis on the behavioural manipulation of its amphipod intermediate host
2012
In trophically-transmitted parasites, exploitation strategies of the intermediate host have been selected, in a way increasing parasites transmission probabilities to their definitive host. Particularly, numerous parasites are able to alter their intermediate host behaviour, a phenomenon called ‘behavioural manipulation’. This manipulation only occurs when the parasite developmental stage (or larval stage) is infective for the definitive host. Before reaching this stage, the development of parasite larvae is not sufficiently advanced to allow establishment in the definitive host (this stage is thus called ‘non-infective’). Early transmission of a non-infective stage therefore implies parasi…
Assessing non-chemical weeding strategies through mechanistic modelling of blackgrass (Alopecurus myosuroides Huds.) dynamics
2010
; Because of environmental and health safety issues, it is necessary to develop strategies that do not rely on herbicides to manage weeds. Introducing temporary grassland into annual crop rotations and mechanical weeding are the two main features that are frequently used in integrated and organic cropping systems for this purpose. To evaluate the contribution of these two factors in interaction with other cropping system components and environmental conditions, the present study updated an existing biophysical model (i.e. AlomySys) that quantifies the effects of cropping system on weed dynamics. Based on previous experiments, new sub-models were built to describe the effects on plant survi…
Fusariose du cyclamen : connaître, détecter et prévenir
2015
SPE Pôle IPM; Fusarium oxysporum est un champignon tellurique ubiquiste présentant une grande diversité de souches pathogènes et non pathogènes. Les souches phytopathogènes sont groupées en formae speciales selon leur spécificité d’hôte. Ainsi, la forma specialis cyclaminis (Focy) est responsable de la fusariose vasculaire du cyclamen. C’est le pathogène le plus destructeur sur cyclamen. Le pathogène, et donc la maladie peuvent intervenir à tout moment du cycle de culture causant d’importantes les pertes. Malheureusement, la détection préventive de Focy n’est pas possible, la lutte chimique inefficace et la résistance variétale inexistante. La lutte biologique apparaît comme l’alternative à…