Search results for " proteomic"
showing 10 items of 171 documents
Differential protein expression in cytokine-sensitive and -resistant pancreatic beta cell lines
2009
Chemical Proteomics-Guided Identification of a Novel Biological Target of the Bioactive Neolignan Magnolol
2019
Understanding the recognition process between bioactive natural products and their specific cellular receptors is of key importance in the drug discovery process. In this outline, some potential targets of Magnolol, a natural bioactive compound, have been identified by proteomic approaches. Among them, Importin-β1 has been considered as the most relevant one. A direct binding between Magnolol and this nuclear chaperone has been confirmed by DARTS and molecular docking, while its influence on Importin-β1 translocation has been evaluated by in vitro assays.
Letter to the Editor: Solution structure of hypothetical protein TA1414 from Thermoplasma acidophilum
2004
Evaluation of cellular response of breast cancer cells grown on distinctive collagen substrates
2008
Multi-omics analysis of epithelial-to mesenchymal transition mediators in breast cancer
2022
Metabolic Signature of Breast Cancer Patients Negative and Positive to 18F-FDG PET Srceening.
2011
Metabolic signature of breast cancer patients negative and positive to 18F-FDG PET screening.
2010
Breast cancer proteomics: from research to clinical applications.
2008
The exponentially increasing volume of information extracted from genomic and proteomic applications on cancer, while providing new insights into molecular composition of cancer cells and tissues, imposes new challenges on data rationalization as a tool for clinically relevant biomarker discovery. Breast cancer represents the most frequent and potentially aggressive type of cancer and, moreover, it is one of the most enigmatic and poorly predictable in its evolution, likely because it includes several different forms that behave differently among patients. Current clinical parameters for breast cancer diagnosis and cure are: tumour size, axillary lymph node status, histological grading and …
Enterotoxinomics: The omic sciences in the study of staphylococcal toxins analyzed in food matrices
2013
Abstract Foodomics covers all several disciplines related with emerging working areas and relies on them to get a broader knowledge about food quality and food safety to improve consumer's well-being, health and confidence. Enterotoxin-producing S. aureus is one of the most common causes of food-borne human illness throughout the world. Because of the possible significance of these enterotoxins for public health and food safety, greater knowledge of their occurrence and an efficient means of screening at the protein level are needed. It is under these circumstances where Enterotoxinomic science has an important role. The term Enterotoxinomics refers to the omic sciences applied to enterotox…