Search results for " protocol"
showing 10 items of 1320 documents
Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt.
2009
Paclitaxel (PTX) and beta-lapachone (LPC) are naturally occurring compounds that have shown a large spectrum of anticancer activity. In this article we show for the first time that PTX/LPC combination induces potent synergistic apoptotic effects in human retinoblastoma Y79 cells. Combination of suboptimal doses of PTX (0.3 nM) and LPC (1.5 microM) caused biochemical and morphological signs of apoptosis at 48 h of treatment. These effects were accompanied by potent lowering in inhibitor of apoptosis proteins and by activation of Bid and caspases 3 and 6 with lamin B and PARP breakdown. PTX/LPC combination acted by favoring p53 stabilization through a lowering in p-Akt levels and in ps166-MDM…
The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon o…
2012
Trials 13, 180 (2012). doi:10.1186/1745-6215-13-180
Integrated treatment of first episode psychosis with online training (e-learning): study protocol for a randomised controlled trial
2014
Background: The integrated treatment of first episode psychosis has been shown to improve functionality and negative symptoms in previous studies. In this paper, we describe a study of integrated treatment (individual psychoeducation complementary to pharmacotherapy) versus treatment as usual, comparing results at baseline with those at 6-month re-assessment (at the end of the study) for these patients, and online training of professionals to provide this complementary treatment, with the following objectives: 1) to compare the efficacy of individual psychoeducation as add-on treatment versus treatment as usual in improving psychotic and mood symptoms; 2) to compare adherence to medication,…
Improved section bonding using silanated glass slides--application protocol.
1992
Silanated slides provide excellent tissue adhesion for routine histology, immunohistochemistry and in situ hybridization of frozen, paraffin embedded material or cell smears. An easy and inexpensive method of treating glass microscope slides with triethoxysilylpropylamine is reported.
A Lightweight Network Discovery Algorithm for Resource-constrained IoT Devices
2019
Although quite simple, existing protocols for the IoT suffer from the inflexibility of centralized infrastructures and require several configuration stages. The implementation of these protocols is often prohibitive on resource-constrained devices. In this work, we propose a distributed lightweight implementation of network discovery for simple IoT devices. Our approach is based on the exchange of symbolic executable code among nodes. Based on this abstraction, we propose an algorithm that makes even IoT resource-constrained nodes able to construct the network topology graph incrementally and without any a priori information about device positioning and presence. The minimal set of executab…
Retrospection in interpreting and translation: explaining the process?
2014
Retrospection is one of the few research methods equally suitable for studying the processes involved in both translation and interpreting. At the first workshop on research methods in process-oriented research (Graz 2009), we presented the results of a pilot study of retrospection as a research method, published as Englund Dimitrova & Tiselius (2009). The study involved data from two groups (15 years of professional experience vs. no professional experience), each with 3+3 subjects (interpreter subjects vs. translator subjects, all with Swedish as their L1). The source text was a 10-minute plenary speech in English from the European Parliament, interpreted simultaneously into Swedish. …
Preamble Sampling MAC Protocol for Low Power Wireless Sensor Networks with IEEE 802.15.4 Transceivers
2006
In this paper a preamble sampling MAC protocol for low power wireless sensor networks is proposed. The article describes the implementation of the protocol using network nodes equipped with the Chipcon CC2420 802.15.4 transceiver. The power consumption of the transceiver has been measured and the MAC protocol has been adapted to the transceiver properties. The results show the trade-off between power consumption and transmission delay for this algorithm during the communication process.
Neuro-ICU patient disposition
2018
This article revises the recent evidence on ICU admission criteria for acute neurological patients [traumatic brain injury (TBI) patients, postoperative neurosurgical procedures and stroke].The appropriate utilization of ICU beds is essential, but it is complex and a challenge to attain. To date there are no widely accepted international guidelines for managing these acute brain-injured patients (stroke, TBI, postneurosurgery) in the ICU. The criteria for ICU admission after neurological acute injury, high-dependency unit or a specialized neurosurgical ward vary from institution to institution depending on local structures and characteristics of the available resources. Better evidence to s…
Langzeitverlauf 10 Jahre nach transpupillarer Thermotherapie (TTT) kleiner, posteriorer maligner Aderhautmelanome
2011
Background The aim of this study was to evaluate the long-term results of transpupillary thermotherapy (TTT) for small malignant choroidal melanomas. Patients and methods In the time period 1/1998 to 10/1999 in a prospective non-randomised analysis 26 eyes with small malignant melanomas (located posterior to the equator with base ≤ 12 and thickness ≤ 4.5 mm) were primary treated with the TTT standard protocol (follow-up over a time span of at least 10 years). Results Thirteen women and thirteen men (mean age: 64 years) underwent TTT. The mean preoperative tumour thickness was 2.45 mm (0.8 - 4.5 mm). Ten years postoperatively tumour regression without recurrence after 1.4 treatment sessions …
Protocolo técnico para la fotografía de fuentes filológicas primarias
2014
con fines documentales, proyectado para garantizar la máxima fidelidad posible al motivo original representado. Tras una descripción detallada del material necesario, seleccionado específicamente en función de las necesidades particulares de la fotografía de textos manuscritos o impresos, se desarrolla un procedimiento adaptado a las nuevas circunstancias de la fotografía digital, concebido en dos fases: la captación de la imagen en formato RAW, y su posterior edición. En este estudio se trata la primera parte, describiendo sistemáticamente, paso a paso, las decisiones técnicas relativas a los ajustes fotográficos de la toma en diferentes situaciones lumínicas, encaminadas a maximizar la ca…