Search results for " protocol"
showing 10 items of 1320 documents
Embedding the Remote Application Control: Visual API for PDA Programming
2009
PDAs are more and more used as advanced adaptive HEI (human-environment interaction) interfaces, thus enabling their users to easily operate applications remotely running in pervasive computing scenarios. Based on a previous implementation, in this paper we discuss the development of a new set of .NET-compliant Application Programming Interfaces to be used within the Visual Studio IDE. Our main goal is to provide programmers with a set of components to be used with the common drag-and-drop operation, in order to embed a remote application control within an application running on the PDA and vice-versa. The interaction relies on ad-hoc communication protocols over a framework devoted to pair…
Laparoscopic lymph node dissection should be performed before fertility preserving treatment of patients with cervical cancer
2012
Objective: The aim of this study is to assess our results of treatment of women with stage I cervical cancer > 2 cm in diameter seeking fertility preservation. Treatment consisted of Laparoscopic Pelvic and Paraaortic Lymphadenectomy (LPPLND), and when no nodal metastasis was detected, neoadjuvant chemotherapy (NACT) followed by radical vaginal trachelectomy (RVT). Patients with positive lymph nodes underwent primary chemoradiation. Methods: A cohort of women younger than 40 years of age with stage I disease > 2 cm who underwent LPPLND and either NACT and RVT or chemoradiation. Oncological outcome was evaluated prospectively. Results: Eighteen women were eligible for this study. Twelve (67%…
Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4] tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and pro…
2013
In order to investigate their anticancer potential, four new pyrazolo[1,2-a]benzo[1,2,3,4]-tetrazinone derivatives, designed through the chemometric protocol VLAK, and three of the most active compounds of the previous series have been evaluated on some cellular events including proliferation, apoptosis induction, and cell cycle. The NCI one dose (10 mu M) screening revealed that the 8,9-di-methyl derivative showed activity against Leukemia (CCRF-CEM) and Colon cancer cell line (COLO 205), reaching 81% and 45% of growth inhibition (GI), respectively. Replacement of the two methyl groups with two chlorine atoms maintained the activity toward Leukemia cell (CCRF-CEM, GI 77%) and selectively e…
Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale
2020
The diagnostic strategy for chronic thromboembolic pulmonary hypertension (CTEPH) is composed of two components required for a diagnosis of CTEPH: the presence of chronic pulmonary embolism and an elevated pulmonary artery pressure. The current guidelines require that ventilation–perfusion single-photon emission computed tomography (VQ-SPECT) is used for the first step diagnosis of chronic pulmonary embolism. However, VQ-SPECT exposes patients to ionizing radiation in a radiation sensitive population. The prospective, multicenter, comparative phase III diagnostic trial CTEPH diagnosis Europe - MRI (CHANGE-MRI, ClinicalTrials.gov identifier NCT02791282) aims to demonstrate whether functional…
Heterogeneity in family firms: contextualising the adoption of family governance mechanisms
2020
PurposeThis research is aimed to better understand what characteristics of family firms create a context in which family governance systems are more frequently adopted.Design/methodology/approachWe analyse a sample of 490 Spanish family businesses using cluster analysis, and we identify four different types of family businesses whose characteristics are associated to the adoption of different family governance systems, i.e. family councils and family protocols. The comparison between clusters of the baseline parameters was performed using one-way analysis of variance (ANOVA) for parametric variables, the χ2 test for parametric variables and Kruskal-Wallis for nonparametric variables. By con…
An Open-Label Phase II Study Evaluating the Safety and Efficacy of Ramucirumab Combined With mFOLFOX-6 as First-Line Therapy for Metastatic Colorecta…
2014
Abstract Author Summary Background. Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR-2) are believed to mediate angiogenesis in colorectal cancer (CRC). Ramucirumab (RAM; IMC-1121B) is a human IgG1 monoclonal antibody that inhibits VEGF ligand binding to VEGFR-2, inhibiting VEGFR-2 activation and signaling. Methods. Patients with metastatic CRC, Eastern Cooperative Oncology Group performance status 0–1, and adequate organ function who had not received chemotherapy for metastatic disease received RAM and the modified FOLFOX-6 regimen every 2 weeks. Endpoints included progression-free survival (PFS), objective response rate, overall survival, and safety. The sample size wa…
Treat and extend versus fixed regimen in neovascular age related macular degeneration: A systematic review and meta-analysis
2020
Purpose: To compare efficacy of treat and extend (T&E) versus fixed regimen treatment protocols in neovascular age-related macular degeneration (nAMD). Methods: Randomized clinical trials (RCTs) comparing T&E versus fixed regimen protocols for nAMD were systematically searched. Primary outcome was to compare the mean best corrected visual acuity (BCVA) change in T&E regimen versus fixed regimen. Secondary outcomes were change in the mean optical coherence tomography (OCT) central retinal thickness (CRT) and mean number of injections. Standardized mean difference (SMD) along with 95% confidence intervals (CIs) were calculated. Random-effect models were used for meta-analyses. Res…
Privacy-preserving scheme for mobile ad hoc networks
2011
This paper proposes a decentralized trust establishment protocol for mobile ad hoc networks (MANETs), where nodes establish security associations. In order to achieve privacy and security, we use homomorphic encryption and polynomial intersection so as to find the intersection of two sets. The first set represents a list of recommenders of the initiator and the second set is a list of trusted recommenders of the responder. The intersection of the sets represents a list of nodes that recommend the first node and their recommendations are trusted by the second node. In our experimental results we show that our scheme is effective even if there are 30 trusted nodes.
Castadiva: A Test-Bed Architecture for Mobile AD HOC Networks
2007
Evaluating and deploying all sorts of protocols and applications designed for wireless ad hoc networks in a real environment is an important and urgent task. Traditionally, all the proposals made rely solely on simulator results. However, as different research groups develop different solutions to solve problems related to these new networks, it becomes more and more important to migrate the proposed solutions to a real environment. In this work we present Castadiva, a test-bed architecture that allows validating software solutions for ad hoc networks using low-cost, of the-shelf devices and open source software. Through a friendly user interface, Castadiva offers the possibility to define …
SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area
2020
Preprint disponible en http://hdl.handle.net/10261/209125