Search results for " protocol"
showing 10 items of 1320 documents
Identification of Synaptic Integration Mode in CA3 Pyramidal Neuron Model
2019
International audience; A morphologically realistic and anisotropic model of CA3 pyramidal neuron was developed to determine the synaptic integration modes the neuron is able to perform. Linearity and nonlinearity were identified in different synaptic locations with varying active mechanisms such as the presence of ionic channels in the dendritic arbor and the types of receptors in the synapse. Quantification of synaptic integration was performed using paired-pulse stimulation protocol and subthreshold input/output (sI/O) transformation. Results show that the mode of synaptic integration is location-dependent while the linearity or nonlinearity in the integration is mainly influenced by the…
Multicast TV over WLAN in a University Campus Network
2009
One of the multimedia services offered by the campus network of the Polytechnic University of Valencia is TV over IP. This service works well in the devices connected directly to the wired network but we have detected some problems when the receivers access to the campus network through wireless IEEE 802.11, especially when devices roam across the Campus. In this paper we propose and evaluate a server-based solution to minimize the packet loss and reduce the lack of service when the mobile devices roam from an Access Point to another Access Point in the wireless network. This solution uses a location system to modify the behaviour of standard multicasting protocols in order to get a near-se…
Multicast access control concept for xDSL-customers
2006
Multicast is a tempting possibility for many broad- band services. It makes possible to deliver one data-stream to several receivers simultaneously. IP-Multicast is based on an open group concept. This means that it is possible for all the users to join the group and thus receive the data. The open concept is also the main reason why multicast has not been taken in wider use. There is two different solution to solve this problem, group access control and multicast data encryption. Group access control mechanisms focuses on restricting the group membership at the users edge device. Traffic encryption scheme relies on end-to-end encryption, so a key management architecture is also needed. We …
Quality of Service Multicasting over Differentiated Services Networks
2003
This paper proposes a solution to support real-time multicast traffic with Quality of Service (QoS) constraints over Differentiated Services (DiffServ) IP networks. Our solution allows multicast users to dynamically join and leave the multicast tree. Moreover, it allows a multicast user which has negotiated a best-effort session to upgrade to a QoS-enabled session. Our solution is backward compatible with the Protocol Independent Multicast (PIM) scheme. It combines two ideas. First, resource availability along a new QoS path is verified via a probe-based approach. Second, QoS is maintained by marking replicated packets with a special DSCP value, before forwarding them on the QoS path.
Decoupling factors on the energy–output linkage: The Spanish case
2007
The recent increase of energy intensity in Spain and the ratification of the Kyoto protocol call for the implementation of energy policies in Spain. In this paper, we investigate the relationship between Gross Domestic Product (GDP) and Energy Consumption (EC) by taking into account several decoupling factors that can affect this linkage. Specifically, we have considered the temporal aggregation of data and its seasonal adjustments, the multivariate methodology, the substitution between EC and other inputs and the technological changes. Empirical tests reveal a long-run relationship between EC and GDP that can only be established in a complete way with a multivariate cointegration analysis.…
Effect of radiofrequency and pelvic floor muscle training in the treatment of women with vaginal laxity: A study protocol
2021
Background Vaginal laxity is an underreported condition that negatively affects women’s sexual function and their relationships. Evidence-based studies are needed to better understand this complaint and to discuss its treatment options. Thus, we present a study protocol to compare the effect of radiofrequency and pelvic floor muscle training in the treatment of women with complaints of vaginal laxity. Methods/Design This is a prospective, parallel-group, two-arm, randomized clinical trial (Registry: RBR-2zdvfp–REBEC). Participants will be randomly assigned to one of the two groups of intervention (Radiofrequency or Pelvic Floor Muscle Training). The study will be performed in the Urogyneco…
Progressive active mobilization with dose control and training load in critically ill patients (PROMOB): Protocol for a randomized controlled trial
2020
The dose of progressive active mobilization is still uncertain. The purpose of this study is to identify if the addition of a protocol of progressive active mobilization with dose and training load control to usual care is effective in reducing the length of stay in intensive care unit (ICU) and the improvement of the functioning, incidence of ICU-acquired weakness (ICUAW), mechanical ventilation duration and mortality rate in patients hospitalized in ICU. It is Double-blind randomised clinical trial. The setting for this trial will be medical and surgical ICU of a university hospital. The study participants will be 118 patients aged> 18 years admitted to ICU for less than 72 hours. Partici…
Expectations, experiences and attitudes of patients and primary care health professionals regarding online psychotherapeutic interventions for depres…
2013
Abstract Background In the year 2020, depression will cause the second highest amount of disability worldwide. One quarter of the population will suffer from depression symptoms at some point in their lives. Mental health services in Western countries are overburdened. Therefore, cost-effective interventions that do not involve mental health services, such as online psychotherapy programs, have been proposed. These programs demonstrate satisfactory outcomes, but the completion rate for patients is low. Health professionals’ attitudes towards this type of psychotherapy are more negative than the attitudes of depressed patients themselves. The aim of this study is to describe the profile of d…
Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition
2020
Abstract The interaction of menin (MEN1) and MLL (MLL1, KMT2A) is a dependency and provides a potential opportunity for treatment of NPM1-mutant (NPM1mut) and MLL-rearranged (MLL-r) leukemias. Concomitant activating driver mutations in the gene encoding the tyrosine kinase FLT3 occur in both leukemias and are particularly common in the NPM1mut subtype. In this study, transcriptional profiling after pharmacological inhibition of the menin-MLL complex revealed specific changes in gene expression, with downregulation of the MEIS1 transcription factor and its transcriptional target gene FLT3 being the most pronounced. Combining menin-MLL inhibition with specific small-molecule kinase inhibitors…
Clustering-Based Algorithm for Connectivity Maintenance in Vehicular Ad-Hoc Networks
2014
International audience; Among recent advances in wireless communication technologies' field, Vehicular Ad-hoc Networks (VANETs) have drawn the attention of both academic and industry researchers due to their potential applications including driving safety, entertainment, emergency applications, and content sharing. VANET networks are characterized by their high mobile topology changes. Clustering is one of the control schemes used to make this global topology less dynamic. It allows the formation of dynamic virtual backbone used to organize the medium access, to support quality of service and to simplify routing. Mainly, nodes are organized into clusters with at least one cluster head (CH) …