Search results for " protocol"
showing 10 items of 1320 documents
Antimetastatic activity of adriamycin in combinations with proteinase inhibitors in mice
1990
The antimetastatic activity of adriamycin in combination with proteinase inhibitors was investigated in mice bearing the metastatic tumors L1210 leukemia, Lewis lung carcinoma or M5076 sarcoma. Leupeptin, a cathepsin B inhibitor, when administered as a single agent was devoid of antimetastatic activity but some therapeutic activity was noted in mice with Lewis lung carcinoma when the agent was administered in combination with adriamysin. Pepstatin A, a cathepsin D inhibitor, had no effect as a single agent in mice with L1210 leukemia but displayed some antimetastatic activity in mice with Lewis lung carcinoma. In mice with M5076 sarcoma the combination of pepstatin A and adriamycin resulted…
L0 trigger for the EMCal detector of the ALICE experiment
2012
Abstract The ALICE experiment at the CERN Large Hadron Collider (LHC) accelerator was designed to study ultra-relativistic heavy-ion collisions. The ALICE Electromagnetic Calorimeter (EMCal) was built to provide measurement of photons, electrons, and jets, and trigger selection of hard-QCD events containing them. The EMCal single-shower L0 trigger, which triggers on large energy deposit within a 4×4 tower sliding window, became operational in 2010. The implementation of the real-time FPGA based algorithm optimized to provide a fast L0 decision is presented.
SU-E-T-343: Valencia Applicator Commissioning Using a Micro-Chamber Array
2014
Purpose: In the commissioning and QA of surface isotope-based applicators, source-indexer distance (SID) has a great influence in the flatness, symmetry and output. To these purposes, methods described in the literature are the use of a special insert at the entrance of dwell chamber or radiochromic films. Here we present the experience with a micro-chamber array to perform the commissioning and QA of Valencia applicators. Methods: Valencia applicators have been used, the classic and the new extra-shielded version. A micro-chamber array has been employed, 1000 SRS (PTW), with 977 liquid filled, 2.3×2.3×0.5 mm3 sized ion chambers covering 11×11 cm2, which spacing is 2.5 mm in the central 5.5…
Energy-Efficient Protocol Design
2015
Recent studies have shown that the total energy consumed by the Internet has followed an increasing trend over the years. A considerable part of this energy is wasted due to an inefficient utilization of edge devices , that is, Personal Computers (PCs) and other user equipment in homes and offices. PCs are often left on even when they are not used (e.g., overnight or during weekends), while other edge devices, such as printers, IP phones, and displays, are typically kept always on , especially in public buildings. A number of solutions have been proposed for eliminating, or reducing, energy wastes caused by edge devices. In this chapter, we propose a general taxonomy for their classificatio…
Understanding 802.11e contention-based prioritization mechanisms and their coexistence with legacy 802.11 stations
2005
The IEEE 802.11e task group has reached a stable consensus on two basic contention-based priority mechanisms to promote for standardization: usage of different arbitration interframe spaces and usage of different minimum/maximum contention windows. The goal of this article is to provide a thorough understanding of the principles behind their operation. To this purpose, rather than limit our investigation to high-level (e.g. throughput and delay) performance figures, we take a closer look at their detailed operation, also in terms of low-level performance metrics (e.g., the probability of accessing specific channel slots). Our investigation on one hand confirms that AIFS differentiation prov…
Polypoid anal melanoma. A case report and review of the literature
2016
Ano-rectal melanoma is an uncommon finding in patients complaining of rectal bleeding and/or anal mass often misinterpreted as a haemorroidal pile.A 55-years-old woman, complaining of rectal bleeding, frequent anal pain and anal mass suspected for haemorroidal thrombosis was referred for evaluation and possible treatment. A brown polypoid mass arising from the anal canal/lower rectum with a maximum diameter of 6 cm was diagnosed. The hystological examination of the neoplasm, transanally removed, revealed the presence of a polypoid melanoma partially involving the resection margin. Nor metastases nor limph-node involvement were found at the total-body CT scan and at a CT-PET. C-KIT examinati…
Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells.
2020
Apigenin is one of the most abundant dietary flavonoids that possesses multiple bio-functions.This study was designed to determine the influence of apigenin on gene expressions, cancer cells, as well as STAT1/COX-2/iNOS pathway mediated inflammation and tumorigenesis in HEK293-STAT1 cells. Furthermore, the cytotoxic activity toward multiple myeloma (MM) cell lines was investigated.Bioinformatic analyses were used to predict the sensitivity and resistance of tumor cells toward apigenin and to determine cellular pathways influenced by this compound. The cytotoxic and ferroptotic activity of apigenin was examined by the resazurin reduction assay. Additionally, we evaluated apoptosis, and cell …
A new road to improve vitamin D and balance through Taopatch® and proprioceptive protocol in Multiple Sclerosis patients
2022
: In multiple sclerosis patients (MS), symptoms such as fatigue, lack of physical energy, spasticity, motor coordination disorders, tremors, dizziness and postural instability are most common. Cattaneo et al. (2007) studied the effects of stability training on MS patients, describing its efficacy in reducing all risks, by improving stability, and strength. The present study aimed to confirm our 2021 results on MS patients, combining the Taopatch® device with a proprioceptive rehabilitation protocol (PRP) targeting strength, balance, and biochemical parameters including vitamin D levels. Twenty MS patients, 8 males and 12 females, volunteered in the study. A KERN MAP Version 1.2 08/2012, Han…
Long-term fracture load of all-ceramic crowns: Effects of veneering ceramic thickness, application techniques, and cooling protocol
2020
Made available in DSpace on 2021-06-25T10:46:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01 Background: To evaluate, in vitro, the effects of the cooling protocol, application technique, and veneering ceramic thickness on the fracture resistance of ceramic crowns with Y-TZP frameworks. Material and Methods: 80 frameworks were made from zirconia by the CAD/CAM technique and divided into 8 groups (n = 10) according to the factors: “application technique” (stratified-L and pressed -P), “thickness” (1 mm and 2 mm), and “cooling protocol” (slow-S and fast-F) of the feldspathic veneering ceramic. After, all crowns were cemented over G10 preparations with resin cement (Panavia F, …
Toward the Standardization of Mitochondrial Proteomics: The Italian Mitochondrial Human Proteome Project Initiative
2017
The Mitochondrial Human Proteome Project aims at understanding the function of the mitochondrial proteome and its crosstalk with the proteome of other organelles. Being able to choose a suitable and validated enrichment protocol of functional mitochondria, based on the specific needs of the downstream proteomics analysis, would greatly help the researchers in the field. Mitochondrial fractions from ten model cell lines were prepared using three enrichment protocols and analyzed on seven different LC-MS/MS platforms. All data were processed using neXtProt as reference database. The data are available for the Human Proteome Project purposes through the ProteomeXchange Consortium with the iden…