Search results for " quality of life."

showing 10 items of 343 documents

RHINASTHMA-Adolescents: a new quality of life tool for patients with respiratory allergy

2014

Background: Specific instruments for health-related quality of life (HRQoL) assessment in adolescents with rhinoconjunctivitis or asthma are available. None of them evaluates rhinitis and asthma together, although they often coexist. Our aim was to validate a HRQoL questionnaire for adolescents with rhinoconjunctivitis, asthma, or both. Methods: A pool of 38 items covering the main symptoms and problems related to respiratory allergy was generated based on literature review, clinical experience, and unstructured interviews to 54 adolescents. The items were randomly listed and presented to 88 consecutive outpatients (44 M; mean age 15.2 3.1). Patients had to indicate which item they had expe…

MaleQuestionnairesadolescents; asthma; health-related quality of life; rhinitis; Conjunctivitis; Female; Humans; Male; Respiratory Hypersensitivity; Young Adult; Quality of Life; QuestionnairesImmunologyasthmaConjunctivitishealth-related quality of lifeYoung Adultrhinitisadolescents; asthma; health-related quality of life; rhinitisadolescentSurveys and QuestionnairesPediatrics Perinatology and Child HealthRespiratory HypersensitivityQuality of LifeImmunology and AllergyHumansFemaleadolescents
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Working-Age Cataract Patients: Visual Results, Reading Performance, and Quality of Life with Three Diffractive Multifocal Intraocular Lenses

2013

Purpose To compare the visual outcomes, reading performance, and quality of life (QoL) of working-age cataractous patients bilaterally implanted with 3 different diffractive multifocal intraocular lenses (MIOLs). Design Two-center, randomized, prospective, double-masked study. Participants Sixty-three consecutive patients (126 eyes) seen at Ophthalmology Section, Palermo and Florence University, Italy, randomized to receive the ReSTOR SN6AD3 (Alcon Laboratories, Inc, Irvine, CA) (20 patients, group A), ReSTOR SN6AD1 (Alcon Laboratories, Inc) (21 patients, group B), or TECNIS ZMA00 (Abbott Medical Optics, Santa Ana, CA) (22 patients, group C) MIOL. Intervention Phacoemulsification. Main Outc…

MaleRefractive errorVisual acuitygenetic structuresMesopic visionmedicine.medical_treatmentMesopic VisionVisual AcuitySettore MED/42 - Igiene Generale E ApplicataLens Implantation IntraocularSickness Impact ProfileSurveys and QuestionnairesMedicineContrast (vision)Prospective StudiesProspective cohort studyOPTICAL-QUALITYmedia_commonLenses IntraocularVision BinocularOUTCOMESMiddle AgedRESTORFemalemedicine.symptomA+3.00 DPhotopic visionDIOPTER ADDITIONmedicine.medical_specialtyINSTITUTE-REFRACTIVE ERRORmedia_common.quotation_subjectMODELSProsthesis DesignCataractDouble-Blind MethodOphthalmologyCONTRAST SENSITIVITYHumansBILATERAL IMPLANTATIONPhacoemulsificationColor Visionbusiness.industrySettore MED/30 - Malattie Apparato VisivoPhacoemulsificationMultifocal intraocular lensmedicine.diseaseeye diseasesOphthalmologyVISIONINSTITUTE-REFRACTIVE ERROR; CONTRAST SENSITIVITY; BILATERAL IMPLANTATION; DIOPTER ADDITION; OPTICAL-QUALITY; A+3.00 D; VISION; RESTOR; OUTCOMES; MODELSReadingQuality of LifeOptometryMultifocal IOL diffractive Quality of lifebusinessFollow-Up Studies
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Changes in health-related quality of life in adolescents and the impact of gender and selected variables: a two-year longitudinal study

2022

Abstract Background Increased knowledge about factors that can impact changes in adolescents’ health-related quality of life (HRQOL) is needed. The present study aimed to investigate possible HRQOL changes in adolescents at 14 and 16 years, and assess the impact of sociodemographic factors, gender, pain, self-esteem, self-efficacy, loneliness, and stress on HRQOL changes over time. Further, to assess HRQOL stratified by gender. Methods A longitudinal study involving 211 adolescents was conducted. Sociodemographic variables, pain, self-esteem, self-efficacy, loneliness, and stress were all assessed with well-validated instruments. KIDSCREEN-27 was used to measure HRQOL. Data were analyzed us…

MaleResilienceAdolescentHealth-related quality of lifeLongitudinal studiesLonelinessPublic Health Environmental and Occupational HealthPainGeneral MedicineAdolescentsStressSelf ConceptSelf EfficacySex FactorsVDP::Medisinske Fag: 700::Helsefag: 800Surveys and QuestionnairesQuality of LifeHumansFemaleLongitudinal StudiesStress Psychological
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Association between sarcopenia and quality of life among adults aged ≥ 65 years from low- and middle-income countries

2022

Background Sarcopenia has been associated with a lower quality of life (QoL). However, studies on this association from low- and middle-income countries (LMICs) are scarce. Aims To examine the association between sarcopenia and QoL, in a large nationally representative sample of older adults from six LMICs. Methods Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Non-severe sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength but no slow gait speed, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. QoL was assessed with the 8-item WHO QoL in…

MaleSarcopeniaAgingCross-Sectional StudiesHand StrengthSmith L. Sánchez G. Veronese N. Soysal P. Kostev K. Jacob L. Oh H. Tully M. Butler L. Parsa A. et al. -Association between sarcopenia and quality of life among adults aged ≥ 65 years from low- and middle-income countries.- Aging clinical and experimental research 2022Quality of LifeHumansLow- and middle-income countries Older adults Quality of life SarcopeniaFemaleGeriatrics and GerontologyDeveloping CountriesAgedAging Clinical and Experimental Research
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Associations between self-efficacy, bullying and health-related quality of life in a school sample of adolescents: a cross-sectional study

2018

Background To better understand health-related quality of life (HRQOL) in adolescents, it is important to gain knowledge about factors associated with HRQOL. Being involved in bullying is a significant threat to health, and social and psychological well-being; further, such problems can last into adulthood. The aim of this study was to explore the role of general self-efficacy (GSE) and bullying in relation to HRQOL. We specifically sought to study the prevalence of bullying, as well as the associations between both bullying and self-efficacy and HRQOL in a sample of adolescents. Methods This was a cross-sectional study of 723 adolescents (12–18 years) attending schools selected using rando…

MaleSelf-efficaciesmedicine.medical_specialtyAdolescentCross-sectional studyHealth-related quality of life030209 endocrinology & metabolismAdolescentsHealth related life qualities03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesIntervention (counseling)EpidemiologyPrevalenceHumansMedicine030212 general & internal medicineChildLife qualitiesSelf-efficacySchoolsNorwaybusiness.industrylcsh:Public aspects of medicinePublic healthPublic Health Environmental and Occupational HealthBullyinglcsh:RA1-1270Self EfficacyhumanitiesPeer reviewSelf efficacyCross-Sectional StudiesVDP::Medisinske Fag: 700::Helsefag: 800HealthQuality of LifeFemaleBiostatisticsSelf-efficacybusinessResearch ArticleClinical psychologyBMC Public Health
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Sleep quality in caregivers of patients with Alzheimer’s disease and Parkinson’s disease and its relationship to quality of life

2012

ABSTRACTBackground: Knowledge about sleep complaints of caregivers of patients with Alzheimer's disease (AD) and Parkinson's disease (PD) is limited, and we lack information about the relationship between caregivers’ sleep problems and their quality of life (QoL).Methods: We evaluated subjective sleep quality and its relationship to QoL in a group of 80 caregivers of patients with AD (ADCG, n = 40) and PD (PDCG, n = 40), and in 150 controls. Information about night-time complaints was collected using the Pittsburgh Sleep Quality Index (PSQI). QoL was measured using the McGill QoL Questionnaire.Results: Eighteen ADCG (45%), 22 PDCG (55%), and 45 (30%) controls reported poor sleep quality. Me…

MaleSleep Wake DisordersCoping (psychology)medicine.medical_specialtyParkinson's diseaseDiseaseSleep Wake DisordersSeverity of Illness IndexPittsburgh Sleep Quality IndexCost of IllnessAlzheimer DiseaseSickness Impact ProfileSurveys and QuestionnairesSeverity of illnessMedicineHumansAgedAged 80 and overAlzheimer’s disease Parkinson’s disease neurodegenerative disorders caregivers sleep depression quality of lifebusiness.industryDepressionParkinson DiseaseMiddle Agedmedicine.diseasePsychiatry and Mental healthClinical PsychologySleep deprivationCaregiversItalyPhysical therapyQuality of LifeRegression AnalysisSleep DeprivationFemaleSettore MED/26 - NeurologiaSelf ReportGeriatrics and Gerontologymedicine.symptomAlzheimer's diseasebusinessGerontologyStress Psychological
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The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
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Health-related quality of life, health literacy and COVID-19-related worries of 16- to 17-year-old adolescents and parents one year into the pandemic…

2022

Abstract Background The uncertain and challenging situation caused by the COVID-19 pandemic affects adolescents and their parents in an exceptional way. More knowledge of health-related quality of life (HRQoL), health literacy (HL) and COVID-19-related worries in adolescents and parents 1 year into the pandemic is needed. The present study aimed to describe HRQoL, HL and COVID-19-related worries of 16- to 17-year-old adolescents and parents of adolescents. Further, to assess the strength of associations between gender, HL, COVID-19-related worries and HRQoL. Methods A cross-sectional study involving 215 adolescents and 320 parents was conducted, exploring HRQoL, HL, COVID-19-related worries…

MaleWorriesParentsAdolescentHealth-related quality of lifePublic Health Environmental and Occupational HealthHealth literacyCOVID-19AdolescentsHealth LiteracyCross-Sectional StudiesVDP::Medisinske Fag: 700::Helsefag: 800Surveys and QuestionnairesQuality of LifeHumansFemalePandemics
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Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.

2013

Our objective was to assess the effects of acetyl-L-carnitine (ALC) with riluzole on disability and mortality of amyotrophic lateral sclerosis (ALS). Definite/probable ALS patients, 40-70 years of age, duration 6-24 months, self-sufficient (i.e. able to swallow, cut food/handle utensils, and walk), and with forced vital capacity (FVC) > 80% entered a pilot double-blind, placebo-controlled, parallel group trial and were followed for 48 weeks. ALC or placebo 3 g/day was added to riluzole 100 mg/day. Primary endpoint: number of patients no longer self-sufficient. Secondary endpoints: changes in ALSFRS-R, MRC, FVC and McGill Quality of Life (QoL) scores. Analysis was made in the intention-to-tr…

Maleamyotrophic lateral sclerosisVital CapacityPlacebo-controlled studyPilot ProjectsGastroenterologylaw.inventionRandomized controlled triallawAcetyl-L-carnitineamyotrophic lateral sclerosis; motor neuron disease; randomized trial; acetyl-l-carnitinerandomized trialAmyotrophic lateral sclerosisAcetylcarnitineALS acetyl-L-carnitineNootropic AgentsRiluzoleMiddle AgedRiluzoleTreatment OutcomeNeurologyCombinationDisease Progressionmotor neuron diseaseDrug Therapy CombinationSettore MED/26 - NeurologiaFemaleAcetylcarnitinemedicine.drugAdultmedicine.medical_specialtyAcetyl-L-carnitine amyotrophic lateral sclerosis motor neuron disease randomized trialDouble blindDouble-Blind MethodDrug TherapyInternal medicinemedicineHumansAgedMED/26 - NEUROLOGIAbusiness.industryDisease progressionmedicine.diseaseAcetyl-L-carnitineSurgeryQuality of LifeAcetylcarnitine; Adult; Aged; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Drug Therapy Combination; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Nootropic Agents; Pilot Projects; Quality of Life; Riluzole; Treatment Outcome; Vital CapacityNeurology (clinical)businessExcitatory Amino Acid Antagonists
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Low doses of transdermal buprenorphine in opioid-naive patients with cancer pain: A 4-week, nonrandomized, open-label, uncontrolled observational stu…

2009

OBJECTIVE: The aim of this study was to evaluate the effect and tolerability of low doses of transdermal (TD) buprenorphine patches in opioid-naive patients with cancer pain. METHODS: This was a nonrandomized, open-label, uncontrolled study in consecutive opioid-naive patients with advanced cancer and moderate pain. TD buprenorphine was initiated at a dose of 17.5 microg/h (0.4 mg/d), with patch changes every 3 days. Doses were then adjusted according to the clinical response. Pain intensity, opioid-related adverse effects, TD buprenorphine doses, and quality of life were monitored over 4 weeks. The time to dose stabilization and indexes of dose escalation were also calculated. RESULTS: Thi…

Malecancer painPainOpioidUncontrolled Studytransdermal buprenorphine cancer pain uncontrolled observational studyDose-Response RelationshipNeoplasmsmedicineHumansPharmacology (medical)Adverse effectAgedPain MeasurementIntractablePharmacologyAnalgesicsbusiness.industryopioidsCancermorphineMiddle Agedbuprenorphine; cancer pain; morphine; opioids; Administration Cutaneous; Aged; Analgesics Opioid; Buprenorphine; Dose-Response Relationship Drug; Female; Humans; Male; Middle Aged; Neoplasms; Pain Measurement; Pain Intractable; Quality of Life; Pharmacology; Pharmacology (medical)buprenorphinemedicine.diseaseClinical trialCutaneousTolerabilityAnesthesiaAdministrationQuality of LifeMorphineFemaleDrugCancer painbusinessmedicine.drugBuprenorphineClinical Therapeutics
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