Search results for " radioterapia"

Dose verification with EPR/alanine dosimeters in Helical Tomotherapy Stereotactic Radiosurgery (HT SRS) treatments

2016

Intracranial stereotactic radiosurgery (SRS) is a technique to deliver an ablative radiation dose with an extremely sharp dose gradient to small brain tumors. This tecnique allows to deliver high doses of radiation to the tumor sparing the surrounding healthy tissue. In this study the accuracy of the dose delivered in a SRS session by a non conventional radiotherapy machine, the TomoTherapy Hi-Art System, was investigated using an "end-to-end" test. This is perfome d by means of alanine Electron Paramagnetic Resonance (EPR) pe llets. The response of these dosimeters is compared to that of gafchromic films which are particularly suitable for two-dimensional dose verification providing accura…

Characterization of Fricke gel dosimeters exposed to clinical photons beams and of MRI dosimetrical applications

2014

Sensibilità e stabilità dei dosimetri gel di tipo Fricke esposti ai fotoni nel range clinico in funzione della concentrazione di ferro e degli additi…

2014

Simulazioni numeriche e test di applicabilità clinica della Diffusion Kurtosis Imaging su tomografi RM da 1.5 Tesla

2014

Atti del Workshop: Tecniche Speciali e Avanzate di Dosimetria e Radioprotezione

2016

Atti del Workshop organizzato dall'Associazione Italiana di Radioprotezione (AIRP) in collaborazione con l'Università degli Studi di Palermo, dal titolo "Tecniche Speciali e Avanzate in Dosimetria e Radioprotezione" che si svolgerà venerdì 24 Giugno a Palermo presso l'Aula Magna del Dipartimento di Fisica e Chimica, Viale delle Scienze Edificio 18. L'evento rientra tra i 210 Eventi organizzati per i 210 anni dalla fondazione dell'Ateneo palermitano su iniziativa del Magnifico Rettore, Prof. Fabrizio Micari. L’evento prevede la discussione di 4 tematiche in ambito della dosimetria e della radioprotezione in campo sanitario ed ambientale (Dosimetria Clinica, Dosimetria Ambientale, Dosimetria …

Misure preliminari su scanner MRI 7T di stabilità nel tempo di Dosimetri gel di tipo Fricke

2016

L’ottimizzazione delle procedure che utilizzano radiazioni ionizzanti in campo medico costituisce un elemento chiave per la sicurezza del paziente e l’esito dei trattamenti radioterapici. In particolare è fondamentale arrecare il minor danno possibile ai tessuti sani circostanti la neoplasia da trattare (Attix, 2004). La misurazione precisa della dose somministrata nei tessuti e la sua mappatura in tre dimensioni sono di fondamentale importanza in termini di riuscita e di pianificazione dei trattamenti radioterapici (Khan, 2009). In questo lavoro sono presentate le misure preliminari effettuate per testare la stabilità temporale di dosimetri gel di tipo Fricke tramite scanner pre-clinico 7T…

Investigation of relaxation times of irradiated Fricke gels by means of nuclear magnetic resonance relaxometry

2016

Fricke gel dosimeters are ideal candidates to provide 3D maps of dose distributions and are particularly useful in the plann ing and verification phase of radiotherapy treatments. One of the most effective experimental techniques to reconstruct dose maps is magnetic resonance imaging (MRI). This measures th e nuclear relaxation times variations induced by irradiation. In this work, we analyzed Fricke gels with and without Xylenol Orange by means of a single side-NMR relaxometer (which is abl e to provide information on both relaxation relaxation times T1 and T2 and is mainly used in the field of diagnostics for Cultural Heritage [1-2] to perform porosimetry meaurements). Our goal was to per…

Non-invasive imaging of biological microstructures by VHF waves

2014

[Radiomics and artificial intelligence: new frontiers in medicine.]

2020

Radiomics is a new frontier of medicine based on the extraction of quantitative data from radiological images which can not be seen by radiologist's naked eye and on the use of these data for the creation of clinical decision support systems. The long-term goal of radiomics is to improve the non-invasive diagnosis of focal and diffuse diseases of different organs by understanding links between extracted quantitative imaging data and the underlying molecular and pathological characteristics of lesions. In the last decade, several studies have highlighted the enormous potential of radiomics in both tumoral and non-tumoral diseases of many organs and systems including brain, lung, breast, gast…

MRgFUS Uterine Fibroids treatments in Sicily: Preliminary Results and comparison of a Semi-Automatic and manual contouring

2013

Background: Traditional surgery for uterine fibroids treatments (e.g. myomectomy, hysterectomy) offers very invasive therapeutic approaches, which not always preserve reproductive potential of the woman. MRgFUS (MR guided Focused UltraSound) is a new and non-invasive technique for uterine fibroids treatment, not requiring hospitalization and recovery time [1]. On June 2011 and July 2012 the first treatments were started at HSR-Giglio Hospital in Cefalù and at University Hospital (DIBIMEF) in Palermo. An initial assessment of MRgFUS treatment was made by computing the thermally-ablated volume of uterine fibroid. This volume was evaluated considering the NPV (Non Perfused Volume) on a post-t…