Search results for " rap"

showing 10 items of 561 documents

Adozione in casi particolari e rapporti di parentela tra adottato e famiglia dell'adottante secondo la Corte costituzionale

2022

Il contributo considera le ricadute della sentenza n. 79/2022 della Corte costituzionale sulle due figure dell'adozione piena e dell'adozione in casi particolari dei minori di età con particolare riferimento alla posizione del bambino adottato in casi particolari e dei legami con la famiglia di origine e con quella del/gli adottante/i. Evidenziate talune aporie del ragionamento della Consulta, riflette criticamente sulla bontà del ricorso all'adozione in casi particolari per dare copertura giuridica al legame tra il genitore d'intenzione non biologico e il nato da gestazione per altri, specie in caso di omogenitorialità, in vista del perseguimento del migliore interesse del minore.

Adozione dei minoriunicità dello stato di figlioadozione pienaadozione in casi particolariSettore IUS/01 - Diritto Privatostrumenti per dare riconoscimento al rapporto con il genitore d'intenzione non biologicovincoli di parentela tra adottato in casi particolari e famiglia dell'adottantefiliazione procreativa e filiazione adottivagestazione per altrimigliore interesse del minoretutela del minore nato da gpa
researchProduct

Rapid Weight Loss Habits before a Competition in Sambo Athletes

2021

Background: Like other combat sports, sambo has competition rules that divide athletes into categories based on gender, age and weight. Athletes in combat sports often resort to rapid weight loss (RWL) methods to be more competitive in lower weight categories and gain an advantage against lighter, smaller and weaker competitors. The aim of this study was to examine the methodology implemented by two different sambo age categories, junior and senior athletes, in order to attain RWL. Methods: The sample consisted of 103 male sambo elite athletes (seniors/juniors: age 28.5 ± 4.3/18.9 ± 0.8

AdultMaleAdolescentVomitingcombat sportseducationSignificant grouplcsh:TX341-641030204 cardiovascular system & hematologyArticleSteam BathTimeweight class03 medical and health sciences0302 clinical medicineWeight lossSurveys and QuestionnairesWeight LossmedicineHumansElite athletesRisks and benefitsDiuretics10. No inequalitySettore M-EDF/02 - Metodi E Didattiche Delle Attivita' SportiveNutrition and DieteticsbiologyAthletesRapid weight lossbusiness.industryAge Factors030229 sport sciencesrapid weight lossbiology.organism_classificationCombat sports Rapid weight loss Weight classAthletesLaxativesPillmedicine.symptombusinesslcsh:Nutrition. Foods and food supplyhuman activitiesMartial ArtsFood ScienceDemographyDietingNutrients
researchProduct

Stress-related psychosocial factors at work, fatigue, and risky driving behavior in bus rapid transport (BRT) drivers

2016

Abstract Introduction There is consistent scientific evidence that professional drivers constitute an occupational group that is highly exposed to work related stressors. Furthermore, several recent studies associate work stress and fatigue with unsafe and counterproductive work behaviors. This study examines the association between stress-related work conditions of Bus Rapid Transport (BRT) drivers and risky driving behaviors; and examines whether fatigue is a mechanism that mediates the association between the two. Method A sample of 524 male Bus Rapid Transit (BRT) operators were drawn from four transport companies in Bogota, Colombia. The participants answered a survey which included an…

AdultMaleAutomobile DrivingPoison controlWorking conditionsHuman Factors and ErgonomicsColombiaStructural equation modelingOccupational safety and health03 medical and health sciencesSocial supportRisk-Taking0302 clinical medicineJob stressSurveys and Questionnaires0502 economics and businessHumansSafety Risk Reliability and QualityFatigueOccupational HealthBus rapid transitRiesgos laborales050210 logistics & transportationJob strainFatiga05 social sciencesPublic Health Environmental and Occupational HealthSocial SupportHuman factors and ergonomics030210 environmental & occupational healthProfessional driversOccupational DiseasesMotor VehiclesAccidentes de tránsitoFemaleSafetyPsychologySocial psychologyPsychosocialStress Psychological
researchProduct

Effect of Sirolimus Exposure on the Need for Preemptive Antiviral Therapy for Cytomeglovirus Infection after Allogeneic Hematopoietic Stem Cell Trans…

2019

The current study evaluates the clinical effect of sirolimus exposure on the occurrence of cytomegalovirus (CMV) DNAemia necessitating preemptive antiviral therapy. A total of 167 consecutive recipients of reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (allo-HSCT) who received sirolimus- and tacrolimus-based graft-versus-host disease (GVHD) prophylaxis and whose CMV serostatus was positive for donors and/or recipients were included in this multicenter retrospective study. A parametric model with consecutive sirolimus blood levels describing the time to CMV DNAemia-RAT was developed using NONMEM version 7.4. Overall, 122 of 167 patients (73%) were all…

AdultMaleOncologymedicine.medical_specialtyPremedicationmedicine.medical_treatmentCongenital cytomegalovirus infectionHematopoietic stem cell transplantationAntiviral AgentsAllogeneic hematopoietic stem cells transplantationMechanistic target of rapamycin inhibitorQuantitative PCR03 medical and health sciences0302 clinical medicineTime-to-event analysisInternal medicineHumansTransplantation HomologousMedicineCumulative incidenceCytomegalovirus diseaseSurvival analysisRetrospective StudiesSirolimusTransplantationDose-Response Relationship Drugbusiness.industryHazard ratioHematopoietic Stem Cell TransplantationPK/PDvirus diseasesRetrospective cohort studyHematologyMiddle Agedmedicine.diseaseCytomegalovirus infectionsurgical procedures operativeCytomegalovirus DNAemia030220 oncology & carcinogenesisSirolimusCytomegalovirus InfectionsPreemptive antiviral therapySirolimus exposureFemalebusinessSerostatusImmunosuppressive Agents030215 immunologymedicine.drug
researchProduct

Relationships of working conditions, health problems and vehicle accidents in bus rapid transit (BRT) drivers

2018

Background The aim of this study was to estimate accident risk rates and mental health of bus rapid transit (BRT) drivers based on psychosocial risk factors at work leading to increased stress and health problems. Methods A cross-sectional research design utilized a self-report questionnaire completed by 524 BRT drivers. Results Some working conditions of BRT drivers (lack of social support from supervisors and perceived potential for risk) may partially explain Bogota's BRT drivers' involvement in road accidents. Drivers' mental health problems were associated with higher job strain, less support from co-workers, fewer rewards and greater signal conflict while driving. Conclusions To preve…

AdultMaleRiskCondiciones de trabajoBRT driversJob controlApplied psychologyPsychological interventionTransportationColombiaOccupational safety and healthOccupational StressSocial supportJob stressSurveys and Questionnaires0502 economics and businessHumansMedicine0501 psychology and cognitive sciences050107 human factorsBus rapid transit050210 logistics & transportationOccupational healthJob strainbusiness.industry05 social sciencesAccidents TrafficPublic Health Environmental and Occupational HealthSocial SupportMiddle AgedMental healthMotor VehiclesCross-Sectional StudiesMental HealthMental healthFemaleEnfermedades cardiovascularesbusinessRisk assessmentEstrés laboralhuman activitiesAmerican Journal of Industrial Medicine
researchProduct

HIV rapid test in a community setting as a strategy to improve access to HIV testing: data from a multicentre experience in Italy

2019

4,000 new HIV diagnoses and approximately 800 AIDS cases are still reported annually in Italy. Improving public awareness and bringing out HIV-undiagnosed individuals are keystones to progress towards the control of the HIV epidemic. For this purpose, the Open HIV TEST project was organized and delivered by the Italian NGO Anlaids, together with local infectious diseases specialists, in order to provide free access to HIV testing outside the healthcare setting. Between October 2017 and February 2019 six Open HIV TEST initiatives were delivered in six Italian cities (3 northern cities, 1 central and 2 southern cities). In all, 581 people were tested: the overall prevalence of HIV test reacti…

AdultMaleTime FactorsAdolescenthealth promotion HIV infection prevention intervention HIV rapid test.AIDS SerodiagnosisHIV InfectionsMiddle AgedSettore MED/42 - Igiene Generale E ApplicataHealth Services AccessibilityYoung AdultItalyPrevalenceHumansFemaleCommunity Health ServicesRetrospective Studies
researchProduct

Intranasal fentanyl versus fentanyl pectin nasal spray for the management of breakthrough cancer pain in doses proportional to basal opioid regimen.

2014

Abstract The aim of this randomized, crossover, comparison study was to assess the analgesic and adverse effects of 2 nasal preparations, intranasal fentanyl (INFS) and fentanyl pectin nasal spray (FPNS), for breakthrough pain, given in doses proportional to opioid basal regimen. Each patient randomly received INFS or FPNS in doses proportional to opioid dosages used for background analgesia for 2 pairs of episodes. For each episode of breakthrough pain, pain intensity and adverse effects intensity were recorded just before starting the INFS or FPNS (T0) and 5 minutes (T5), 10 minutes (T10), and 20 minutes (T20) after the administration of the nasal drugs. Sixty-nine patients were studied. …

AdultMalefentanyl pectin nasal spraymedicine.medical_treatmentAnalgesicSettore MED/42 - Igiene Generale E ApplicataFentanylrapid-onset opioidsNeoplasmsparasitic diseasesMedicineHumansCancer painAdverse effectAgedPain MeasurementAged 80 and overDose-Response Relationship Drugbusiness.industryBreakthrough Painintranasal fentanylNasal SpraysMiddle AgedCancer pain; breakthrough pain; fentanyl pectin nasal spray; intranasal fentanyl; rapid-onset opioidsAnalgesics OpioidFentanylRegimenAnesthesiology and Pain MedicineCross-Sectional StudiesNeurologyOpioidNasal sprayAnesthesiaPectinsNasal administrationFemaleNeurology (clinical)businessCancer painmedicine.drugThe journal of pain
researchProduct

Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
researchProduct

Towards a new mix design method for asphalt mixtures containing rap

2016

Recycling is one of the most important aspects to conceive the new construction or rehabilitation of sustainable road infrastructures. Even if Reclaimed Asphalt Pavement (RAP) is commonly used in the practice, its presence may lead to some critical aspects due to the physical and chemical phenomena occurring during the new mix process. For instance, the formation of RAP clusters during a new mix may inhibit the uniform distribution of the virgin binder as well as cause changes in the design grading curve of the mixture. Indeed, laboratory results demonstrate that small-size RAP particles stick together forming clusters. The amount of clusters depends on different parameters observed: The pe…

AgingWaste managementAsphaltrubber modifiedMix designBuilding and ConstructionMix designClusteringAsphalt mixtureAsphaltAging; Asphalt mixture; Clustering; Mix design; RAP; Building and Construction; Civil and Structural EngineeringSettore ICAR/04 - Strade Ferrovie Ed AeroportiEnvironmental scienceAsphalt pavementRAPCivil and Structural Engineering
researchProduct

CB1 cannabinoid receptor-mediated aggressive behavior

2013

This study examined the role of cannabinoid CB1 receptors (CB1r) in aggressive behavior. Social encounters took place in grouped and isolated mice lacking CB1r (CB1KO) and in wild-type (WT) littermates. Cognitive impulsivity was evaluated in the delayed reinforcement task (DRT). Gene expression analyses of monoaminooxidase-A (MAO-A), catechol-o-methyl-transferase (COMT), 5-hydroxytriptamine transporter (5-HTT) and 5-HT1B serotonergic receptor (5HT1Br) in the median and dorsal raphe nuclei (MnR and DR, respectively) and in the amygdala (AMY) were performed by real time-PCR. Double immunohistochemistry studies evaluated COMT and CB1r co-localization in the raphe nuclei and in the cortical (AC…

AgonistMalemedicine.medical_specialtyCannabinoid receptorTime Factorsmedicine.drug_classmedicine.medical_treatmentPoison controlArachidonic AcidsSerotonergicCatechol O-MethyltransferaseAmygdalaCellular and Molecular NeuroscienceMiceDorsal raphe nucleusReceptor Cannabinoid CB1Internal medicinemedicineAnimalsInterpersonal RelationsMonoamine OxidasePharmacologyCannabinoid Receptor AgonistsMice KnockoutSerotonin Plasma Membrane Transport ProteinsAmygdalaSurgeryAggressionmedicine.anatomical_structureEndocrinologynervous systemGene Expression RegulationImpulsive BehaviorReceptor Serotonin 5-HT1BConditioning OperantRaphe NucleiCannabinoidRaphe nucleiPsychologyReinforcement Psychology
researchProduct