Search results for " rap"
showing 10 items of 561 documents
Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity an…
2015
New findings show existence of FGFR1-5-HT1A heteroreceptor complexes in 5-HT nerve cells of the dorsal and median raphe nuclei of the rat midbrain and hippocampus. Synergistic receptor-receptor interactions in these receptor complexes indicated their enhancing role in hippocampal plasticity. The existence of FGFR1-5-HT1A heteroreceptor complexes also in midbrain raphe 5-HT nerve cells open up the possibility that antidepressant drugs by increasing extracellular 5-HT levels can cause an activation of the FGF-2/FGFR1 mechanism in these nerve cells as well. Therefore, the agonist modulation of the FGFR1-5-HT1A heteroreceptor complexes and their specific role is now determined in rat medullary …
Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor int…
2015
The ascending midbrain 5-HT neurons known to contain 5-HT1A autoreceptors may be dysregulated in depression due to a reduced trophic support. New findings show existence of FGFR1-5-HT1A heteroreceptor complexes in the rat hippocampus with a partial characterization of their interface and in midbrain raphe 5-HT nerve cells. With in situ Proximity Ligation Assay (PLA) and supported by co-location of the FGFR1 and 5-HT1A immunoreactivities in midbrain raphe 5-HT cells, evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes were obtained in the dorsal and median raphe nuclei of the Sprague–Dawley rat. Their existence in the rat medullary raphe RN33B cell cultures was also establish…
Caractérisation quantitative de la pulvérisation de pesticides par imagerie
2015
In recent years, advances in plant protection have contributed considerably to increasing crop yields in a sustainable way. Easy to apply and rather inexpensive, pesticides have proven to be very efficient. However, when pesticides are applied to crops some of the spray may not reach the target, but move outside the intended spray area. This can cause serious economic and environmental problems. Most of the pesticides are applied using agricultural sprayers. These sprayers use hydraulic nozzles which break the liquid into droplets with a wide range of droplet sizes and velocities and determine the spray pattern. Small droplets are prone to wind drift, while large droplets can runoff from th…
Introduzione
2014
L’opera di Vincenza Garofalo, “Unbuilt. Quattro progetti di Alberto Sartoris", assume la forma di una ricerca fondata su un dispositivo metodologico e culturale ampio che penetra in profondità nei territori dell’analisi filologica, dell’estetica, della critica architettonica e, naturalmente, della “Scienza della Rappresentazione”. Il campo di indagine è quello degli esiti di una sperimentazione progettuale che non si traduce in concreta forma fisica, per mezzo dell’atto del costruire, e che per questo necessita di pratiche esperenziali estese che implicano maggiori livelli di approfondimento critico-relazionali e specificità disciplinari in grado di fare avanzare la “percezione” in direzion…
Altari del Settecento a Catania. Storia, rilievo e rappresentazione di tre casi studio
2022
Il contributo affronta il tema degli altari a doppio ordine settecenteschi conservati a Catania nelle chiese di San Giuliano, San Placido e Santa Chiara. A partire dal rilievo strumentale, l'analisi grafica e tipologica dei manufatti viene integrata con le informazioni documentarie e bibliografiche note. La rappresentazione digitale degli altari consente di chiarire specifiche questioni relative a modelli e scelte progettuali.
un approccio teorico-sperimentale per la ricostruzione del profilo trasversale di rotaie usurate
2012
La sovrastruttura ferroviaria durante la sua vita utile è sottoposta oltre ai carichi dinamici generati dai rotabili (azioni verticali, laterali, ecc.), anche ai carichi termici e ad azioni ambientali di varia natura. Tali sollecitazioni, interagendo sinergicamente tra loro, determinano il deterioramento della sovrastruttura ferroviaria inteso come discostamento dalla configurazione geometrica di progetto e l’usura dei singoli componenti del binario e della massicciata. Per valutare lo stato di efficienza della sovrastruttura è consuetudine far riferimento ad alcuni parametri geometrici del binario che, peraltro, permettono di formulare un giudizio oggettivo circa il livello di sicurezza of…
Analisi delle rappresentazioni. Uno studio delle opere di E. Goffman (1922-1982).
2012
Common genetic denominators for Ca++-based skeleton in Metazoa: role of osteoclast-stimulating factor and of carbonic anhydrase in a calcareous spong…
2012
Calcium-based matrices serve predominantly as inorganic, hard skeletal systems in Metazoa from calcareous sponges [phylum Porifera; class Calcarea] to proto- and deuterostomian multicellular animals. The calcareous sponges form their skeletal elements, the spicules, from amorphous calcium carbonate (ACC). Treatment of spicules from Sycon raphanus with sodium hypochlorite (NaOCl) results in the disintegration of the ACC in those skeletal elements. Until now a distinct protein/enzyme involved in ACC metabolism could not been identified in those animals. We applied the technique of phage display combinatorial libraries to identify oligopeptides that bind to NaOCl-treated spicules: those oligop…
Contribution of sponge genes to unravel the genome of the hypothetical ancestor of Metazoa (Urmetazoa)
2001
Recently the term Urmetazoa, as the hypothetical metazoan ancestor, was introduced to highlight the finding that all metazoan phyla including the Porifera (sponges) are derived from one common ancestor. Sponges as the evolutionarily oldest, still extant phylum, are provided with a complex network of structural and functional molecules. Analyses of sponge genomes from Demospongiae (Suberites domuncula and Geodia cydonium), Calcarea (Sycon raphanus) and Hexactinellida (Aphrocallistes vastus) have contributed also to the reconstruction of the evolutionary position of Metazoa with respect to Fungi. Furthermore, these analyses have provided evidence that the characteristic evolutionary novelties…