Search results for " reactions"

Adsorption and Activation of Water on Cuboctahedral Rhodium and Platinum Nanoparticles

2017

Rh and Pt are widely used as the components in heterogeneous catalysts for multiple industrial applications. Because the metals are typically in the form of nanoparticles in real catalysts, it is important to carefully select models for the computational prediction of the catalytic properties. Here we report a first-principles study on the water activation, an important step in numerous catalytic reactions, using the finite-size Rh and Pt nanoparticle models and compare them to the extended surface models. We show that regardless of the model, adsorption and activation of water is practically identical for both metals, whereas the dissociation is energetically more favorable on Rh. The expe…

Ultraviolet B radiation induced alterations in immune function of fish : in relation to habitat preference and disease resistance

2009

Runsas altistuminen auringolle on tunnetusti haitallista ihmisten ja eläinten hyvinvoinnille. Eveliina Markkula tutki väitöskirjatyössään, miten ultravioletti B (UVB) -säteilylle altistuminen vaikuttaa kalojen vastustuskykyyn ja tautialttiuteen.- Ilmakehän otsonikerroksen oheneminen viime vuosikymmenten aikana on johtanut UVB-säteilyn lisääntymiseen maan pinnalla. UVB-säteily tunkeutuu myös kirkkaisiin järvi- ja merivesiin ja voi näin aiheuttaa haittaa kaloille, Markkula kertoo.UVB-säteilyn on jo aiemmin todettu lisäävän kalojen varhaisten elinvaiheiden epämuodostumia ja kuolleisuutta. Kertaluonteinenkin altistuminen lampuilla tuotetulle UVB-säteilylle aiheuttaa muutoksia kalan immuunijärje…

Could PD-1/PDL1 immune checkpoints be linked to HLA signature?

2019

The outstanding clinical expansion of monoclonal antibodies (mAbs) to programmed cell death receptor-1 (PD-1) (nivolumab and pembrolizumab) and PD-1 ligand-1 (PDL-1) (atezolizumab, avelumab and durvalumab) has received an increasing level of interest regarding immunotherapy and multidrug combinations, for the treatment of a number of common human malignancies. Some patients treated with these agents receive remarkable benefits in term of quality of life, progression-free (PFS) and overall survival (OS). However, a significant percentage of these patients experience immune-related adverse events (irAEs), while others present with an ultra-rapid disease progression, defined as hyperprogressio…

Human Papillomavirus Type 16 E7 Peptide-Directed CD8+ T Cells from Patients with Cervical Cancer Are Cross-Reactive with the Coronavirus NS2 Protein

2003

ABSTRACTHuman papillomavirus type 16 (HPV16) E6 and E7 oncoproteins are required for cellular transformation and represent candidate targets for HPV-specific and major histocompatibility complex class I-restricted CD8+-T-cell responses in patients with cervical cancer. Recent evidence suggests that cross-reactivity represents the inherent nature of the T-cell repertoire. We identified HLA-A2 binding HPV16 E7 variant peptides from human, bacterial, or viral origin which are able to drive CD8+-T-cell responses directed against wild-type HPV16 E7 amino acid 11 to 19/20 (E711-19/20) epitope YMLDLQPET(T) in vitro. CD8+T cells reacting to the HLA-A2-presented peptide from HPV16 E711-19(20)recogni…

The science case of the FRS Ion Catcher for FAIR Phase-0

2019

The FRS Ion Catcher at GSI enables precision experiments with thermalized projectile and fission fragments. At the same time it serves as a test facility for the Low-Energy Branch of the Super-FRS at FAIR. The FRS Ion Catcher has been commissioned and its performance has been characterized in five experiments with 238U and 124Xe projectile and fission fragments produced at energies in the range from 300 to 1000 MeV/u. High and almost element-independent efficiencies for the thermalization of short-lived nuclides produced at relativistic energies have been obtained. High-accuracy mass measurements of more than 30 projectile and fission fragments have been performed with a multiple-reflection…

Production cross section and decay study of $^{243}$Es and $^{249}$Md

2019

In the study of the odd-$Z$, even-$N$ nuclei $^{243}$Es and $^{249}$Md, performed at the University of Jyv\"askyl\"a, the fusion-evaporation reactions $^{197}$Au($^{48}$Ca,2$n$)$^{243}$Es and $^{203}$Tl($^{48}$Ca,2$n$)$^{249}$Md have been used for the first time. Fusion-evaporation residues were selected and detected using the RITU gas-filled separator coupled with the focal-plane spectrometer GREAT. For $^{243}$Es, the recoil decay correlation analysis yielded a half-life of $24 \pm 3$s, and a maximum production cross section of $37 \pm 10$ nb. In the same way, a half-life of $26 \pm 1$ s, an $\alpha$ branching ratio of 75 $\pm$ 5%, and a maximum production cross section of 300 $\pm$ 80 nb…

Transfer reactions in 206Pb+118Sn: From quasielastic to deep-inelastic processes

2023

We measured multinucleon transfer reactions for the 206Pb+118Sn system at Elab=1200 MeV by employing the large solid angle magnetic spectrometer PRISMA. Differential and total cross sections and Q-value distributions have been obtained for a variety of neutron and proton pick-up and stripping channels. The Q-value distributions show how the quasielastic and deep inelastic processes depend on the mass and charge of the transfer products. The corresponding cross sections have been compared with calculations performed with the grazing code. An overall good agreement is found for most of the few nucleon transfer channels. The underestimation of the data for channels involving a large number of …

Study of non-fusion products in the 50Ti + 249Cf reaction

2018

Physics letters / B B 784, 199 - 205 (2018). doi:10.1016/j.physletb.2018.07.058

Production cross section and decay study of 243Es and 249Md

2019