Search results for " regression"

showing 10 items of 1835 documents

Can We Define the Risk of Lymph Node Metastasis in Early-Stage Cervical Cancer Patients? A Large-Scale, Retrospective Study

2017

BACKGROUND: Sentinel lymph node (SLN) biopsy has emerged as one of the most appreciated techniques for reducing the rate of complete lymph node dissection (LND) performed in patients with early-stage cervical cancer (ECC). However, its performances are still a matter of debate and, to improve them, international guidelines recommend performing at least unilateral LND in case of SLN mapping. In a prior study, we identified a group of patients without evidence of lymph node metastasis (LNM). Our objective is to define a precise risk of LNM for each ECC patient in order to significantly tailor surgery for ECC. METHODS: Clinical and pathological data of ECC patients were retrospectively collect…

AdultAdenocarcinoma; Adult; Aged; Aged 80 and over; Carcinoma Squamous Cell; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Middle Aged; Prognosis; Retrospective Studies; Risk Factors; Survival Rate; Uterine Cervical Neoplasms; Young Adult; Lymph Node Excision; Sentinel Lymph Node Biopsy0301 basic medicinemedicine.medical_specialtySentinel lymph nodeUterine Cervical NeoplasmsAdenocarcinomaLogistic regressionYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsmedicineHumansStage (cooking)Large-Scale Retrospective Study Sentinel lymph node (SLN) biopsy Lymphadenectomy (LND) early-stage cervical cancer (ECC)Lymph nodeAgedRetrospective StudiesAged 80 and overCervical cancerSentinel Lymph Node Biopsybusiness.industryRetrospective cohort studyMiddle AgedPrognosismedicine.diseaseSurgerySurvival Ratecervical cancer lymph nodes metastasesDissectionExact testSettore MED/40 - GINECOLOGIA E OSTETRICIA030104 developmental biologymedicine.anatomical_structureOncologyLymphatic Metastasis030220 oncology & carcinogenesisSurgery; OncologyCarcinoma Squamous CellLymph Node ExcisionFemaleSurgeryRadiologybusinessFollow-Up StudiesAnnals of Surgical Oncology
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Socio-demographic characteristics are related to the advanced clinical stage of oral cancer

2019

Background Social determinants may be associated with the onset and progression of the clinical stage of oral cancer. Aim: To evaluate the impact of socio-demographic characteristics on the prevalence of advanced clinical stage of oral cancer. Material and Methods Information about 51,116 cases of oral cancer, from all Brazilian states, between 2000 and 2012, was obtained from the Cancer Registry Information System. The clinical stage of oral cancer (dependent variable) was classified as initial (stages I and II) or advanced (stages III and IV). The relationship between the clinical stage of oral cancer and the following independent variables was analyzed: sex, age, schooling, marital statu…

AdultAdolescentReferralLogistic regressionYoung Adult03 medical and health sciences0302 clinical medicinePrevalenceHumansMedicineFamily historyYoung adultGeneral DentistryMouth neoplasmOral Medicine and PathologyMarital Statusbusiness.industryResearchCancer030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCancer registrySocioeconomic FactorsOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASMarital statusMouth NeoplasmsSurgerybusinessBrazilDemographyMedicina Oral Patología Oral y Cirugia Bucal
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Rheological blood behavior is not only influenced by cardiovascular risk factors but also by aging itself. Research into 927 healthy Spanish Mediterr…

2013

It is not well-established whether the alterations that the hemorheological profile undergoes with aging are an effect of concomitant cardiovascular risk factors or are due to age itself. To clarify this issue, we investigated the effect of age on blood rheology in a population of 927 healthy subjects from eastern Spain aged between 16-85 years, divided into four age groups (<30, 30-44, 45-50, ≥60 years) with and without cardiovascular risk factors. We determined blood viscosity, corrected blood viscosity (BVc), plasma viscosity (PV), erythrocyte aggregation (EA), erythrocyte deformability (EEI60) and fibrinogen, along with glucose and plasma lipids. We found that corrected blood viscosity …

AdultBlood GlucoseErythrocyte AggregationMalemedicine.medical_specialtyAgingAdolescentPhysiologyBlood viscosityPopulationFibrinogenLogistic regressionErythrocyte aggregationYoung AdultRisk FactorsPhysiology (medical)Internal medicineMedicineErythrocyte deformabilityHumanseducationMean corpuscular volumeAgedAged 80 and overeducation.field_of_studymedicine.diagnostic_testbusiness.industryAge FactorsFibrinogenHematologyMiddle AgedLipidsEndocrinologyCardiovascular DiseasesSpainConcomitantImmunologyHemorheologyFemaleCardiology and Cardiovascular Medicinebusinessmedicine.drugClinical hemorheology and microcirculation
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Influence of lifelong cumulative HIV viremia on long-term recovery of CD4+ cell count and CD4+/CD8+ ratio among patients on combination antiretrovira…

2015

OBJECTIVE We explored the impact of lifelong cumulative HIV viremia on immunological recovery during antiretroviral therapy, according to the timing of treatment initiation. METHODS We estimated lifelong cumulative HIV viremia in patients followed in the ANRS PRIMO cohort since primary infection, including 244 patients who started treatment during PHI and had at least one treatment interruption, and 218 patients who started treatment later but with no interruptions. The impact of cumulative viremia on current immunological status was analysed using linear and logistic regression models. RESULTS At the last visit on treatment, median CD4 cell count was 645 cells/μl in the early/intermittent …

AdultCD4-Positive T-LymphocytesMalePercentilemedicine.medical_specialtyTime FactorsImmunologyCD4-CD8 RatioHuman immunodeficiency virus (HIV)CD4-CD8 RatioHIV InfectionsViremiaCD8-Positive T-Lymphocytesmedicine.disease_causeLogistic regressionMedication AdherenceCohort StudiesAntiretroviral Therapy Highly ActiveInternal medicineSecondary PreventionmedicineHumansImmunology and AllergyLongitudinal StudiesProspective StudiesViremiaCd4 cell countbusiness.industrymedicine.diseaseAntiretroviral therapyCD4 Lymphocyte CountInfectious DiseasesAnti-Retroviral AgentsCohortImmunologyFemalebusinessAIDS
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Adverse Childhood Experiences Among 28,047 Norwegian Adults From a General Population

2021

Aim: The purpose of this study was to estimate the prevalence of adverse childhood experiences (ACEs) among Norwegian adults from a general population and to identify potential associations with demographic and socioeconomic characteristics.Methods: A randomly drawn sample (N = 61,611) from the public registry of inhabitants was invited to participate in the Norwegian Counties Public Health Survey. The present study was based on online responses from 28,047 adults ≥18 years (mean age: 46.9 years, SD = 16.03). Log-link binomial regression analyses were performed to examine associations between four measures of ACEs (family conflict, lack of adult support, bad memories, and difficult childhoo…

AdultChild abusemedicine.medical_specialtychild abuseBinomial regressionmedia_common.quotation_subjectPopulationsocioeconomic factorsNorwegian03 medical and health sciences0302 clinical medicineDivorcePrevalencemedicineHumans030212 general & internal medicinefamily conflicteducationSocioeconomic statusOriginal Researchmedia_commoneducation.field_of_studybusiness.industry030503 health policy & servicesPublic healthPublic Health Environmental and Occupational HealthMiddle Agedlanguage.human_languagePeer reviewVDP::Medisinske Fag: 700::Helsefag: 800adult survivors of child adverse eventslanguageEducational StatusPublic Healthadverse childhood experiencesPublic aspects of medicineRA1-12700305 other medical sciencebusinessWelfareDemography
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Can novel early non-invasive biomarkers of embryo quality be identified with time-lapse imaging to predict live birth?

2019

AbstractSTUDY QUESTIONCan time-lapse imaging systems make it possible to identify novel early non-invasive biomarkers to predict live birth?SUMMARY ANSWERFrom mostly high-grade embryos, out of 35 morphometric, morphologic and morphokinetic variables, only pronuclei (PN) position at time of PN juxtaposition and the absence of multinucleated blastomeres at the 2-cell stage (MNB2cell), were potentially associated with live birth.WHAT IS KNOWN ALREADYPrevious studies indicate that some kinetic markers may be predictive of blastocyst development and embryonic implantation. Certain teams have suggested including some of them in decisional algorithms for embryo transfers.STUDY DESIGN, SIZE, DURATI…

AdultEmbryologymedicine.medical_specialtyPregnancy RatePopulationEmbryonic DevelopmentFertilization in VitroLogistic regressionICSITime-Lapse Imaginglive birthOddsembryo morphologyEmbryo Culture Techniques03 medical and health sciences0302 clinical medicinePregnancymedicineHumansembryo kineticsBlastocysteducationRetrospective Studies030304 developmental biology0303 health scienceseducation.field_of_study030219 obstetrics & reproductive medicinePronucleusObstetricsbusiness.industryRehabilitationembryo morphometric parametersObstetrics and GynecologyEmbryoEmbryo TransferBlastocystmedicine.anatomical_structureReproductive Medicinetime-lapse imaging systemOriginal ArticleFemalebusinessLive birthBiomarkersEmbryo qualityHuman Reproduction
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The Happy-Productive Worker Model and Beyond: Patterns of Wellbeing and Performance at Work

2019

According to the happy-productive worker thesis (HPWT), &ldquo

AdultEmploymentMaleIMPACTHealth Toxicology and MutagenesisHappinesslcsh:Medicine050109 social psychologyEnvironmental Sciences & EcologyEfficiencyDisease clusterLogistic regressionGOALSEudaimoniaORGANIZATIONAL CITIZENSHIPArticleJob SatisfactionRATINGShappy-productive worker0502 economics and businessCovariateHumans0501 psychology and cognitive sciencesoccupational wellbeingWork PerformancePublic Environmental & Occupational HealthHAPPINESSScience & Technology05 social scienceslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedJOB-SATISFACTIONWork (electrical)SpainYOUNGFemaleEMPLOYEESHEALTHPsychologySocial psychologyLife Sciences & Biomedicine050203 business & managementEnvironmental SciencesperformanceInternational Journal of Environmental Research and Public Health
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Factors associated with second-hand smoke exposure in non-smoking pregnant women in Spain: self-reported exposure and urinary cotinine levels.

2014

The aim of this study was to evaluate the main sources of and sociodemographic factors associated with second-hand smoke (SHS) exposure, assessed both by questionnaire and by urinary cotinine (UC) levels, in non-smoking pregnant women. We conducted a cross-sectional study in pregnant women from 4 different regions in Spain. A total of 1783 non-smoking pregnant women completed a questionnaire about their previous smoking habit and SHS exposure in their 3rd trimester of pregnancy and provided a urine sample for measuring UC levels. We used logistic regression models to assess the relationship between several sociodemographic variables and some potential sources of SHS exposure. In addition, w…

AdultEnvironmental EngineeringPassive smokingUrinary systemLower riskmedicine.disease_causeLogistic regressioncomplex mixtureschemistry.chemical_compoundYoung AdultPregnancyEnvironmental healthEnvironmental ChemistryMedicineHumansCotinineWaste Management and DisposalSecond hand smoke exposureSmokePregnancyInhalation Exposurebusiness.industrySmokingmedicine.diseasePollutionhumanitieschemistryMaternal ExposureSpainFemaleTobacco Smoke PollutionbusinessCotinineThe Science of the total environment
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Influence of inflammatory and lipidic parameters on red blood cell distribution width in a healthy population

2015

Red blood cell distribution width (RDW) is a routine red blood cell count parameter which has been shown to be associated with inflammatory parameters. Recently, some authors proposed that RDW seems to be a marker of an adverse lipidic profile. In order to clarify whether RDW is related to inflammation, plasma lipids, or both, we determined anthropometric, hematimetric, inflammatory and lipidic parameters in 1111 healthy subjects. RDW correlated directly with age, body mass index (BMI), inflammatory parameters (plasma viscosity, erythrocyte sedimentation rate (ESR), fibrinogen, leukocyte and neutrophil count), and inversely with iron and hematimetric parameters (P  0.05). When subjects were…

AdultErythrocyte IndicesMalemedicine.medical_specialtyPhysiologyInflammationFibrinogenPhysiology (medical)Internal medicineLinear regressionHumansMedicineInflammationmedicine.diagnostic_testbusiness.industryRed blood cell distribution widthHematologyMiddle AgedLipidsHealthy VolunteersEndocrinologySpainErythrocyte sedimentation rateAbsolute neutrophil countFemaleHemoglobinmedicine.symptomCardiology and Cardiovascular MedicinebusinessBody mass indexBiomarkersmedicine.drugClinical Hemorheology and Microcirculation
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Cardiorespiratory Fitness Is Associated With Drop Out From Sport in Norwegian Adolescents. A Longitudinal Study

2020

Several studies indicate that participation in organized sport may result in higher physical activity levels among youth which are associated with high levels of cardiorespiratory fitness. However, no study has examined whether cardiorespiratory fitness (VO2peak) is associated with drop out from sport. The study was a 5-year longitudinal study which followed a sample of adolescents, with measures of cardiorespiratory fitness, weight and height between the age of 14 and 19 yrs. Self-reported data about participation in sport, active commuting and physical activity level were also included. Through logistic regression analyses we found a positive association between cardiorespiratory fitness …

AdultGerontologyLongitudinal studyAdolescentlongitudinalorganized sportNorwegianOverweightLogistic regressionYoung Adult03 medical and health sciences0302 clinical medicinemedicineHumansLongitudinal Studies030212 general & internal medicineChildCompetence (human resources)VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771Original Researchcardiorespiratory fitnessNorwaylcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthCardiorespiratory fitnesslcsh:RA1-1270030229 sport scienceslanguage.human_languagePhysical activity levelPeer reviewPhysical FitnessChild Preschoollanguagedrop outadolescencePublic Healthmedicine.symptomPsychologyhuman activitiesSportsFrontiers in Public Health
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