Search results for " rene."
showing 10 items of 258 documents
Tropical Fruits as an Opportunity for Sustainable Development in Rural Areas: The Case of Mango in Small-Sized Sicilian Farms
2018
Over the last decades, in many rural areas in Southern Europe, farmers have abandoned agricultural activity, especially on small-sized farms, leading to an exodus from rural areas towards urbanized ones. In this context, in the early 1980s, some Sicilian farmers introduced mango on their small-sized farms, as certain areas of Sicily are well suited to tropical and subtropical crops, but also to meet increasing consumer interest for these fruits, as they are perceived as functional foods. This paper aimed to evaluate the economic sustainability of mango and to determine whether its introduction could be considered as an alternative to traditional crops. In particular, an economic-financial a…
New Clones and Old Varieties: Quality of Sicilian Hillside Apple Cultivation
2021
Aims: The aim of this study is to evaluate the qualitative characteristics of the new clones according to the Mediterranean hillside growing environment and, at the same time, to highlight the qualitative peculiarities of the old varieties in order to avoid genetic loss. Introduction: Several apple varieties are constantly selected for improved quality traits and introduced for cultivation and marketing in addition to a few traditional and affirmed varieties. On the other side, local genotype and ancient varieties are still valorised due to the request of a niche market. Methods: We have studied the physico-chemical quality and the sensory traits of the fruit obtained in this particular en…
Assessment of genetically modified maize GA21 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐005)
2017
Efsa Panel On Genetically Modified Organisms (gmo) Requestor: European Commission (DG SANTE)Question number: EFSA-Q-2016-00714Correspondence; Following the submission of application EFSA-GMO-RX-005 under Regulation (EC) No 1829/2003 from Syngenta Crop Protection NV/SA, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of authorisation application of the herbicide-tolerant genetically modified maize GA21. The data received in the context of this renewal application contained post-market environmental monitoring reports, a systematic search and eval…
Energy Policies and Sustainable Management of Energy Sources
2017
Sustainability of current energy policies and known mid-term policies are analised in their multiple facets. First an overview is given about the trend of global energy demand and energy production, analysing the share of energy sources and the geographic distribution of demand, on the basis of statistics and projections published by major agencies. The issue of sustainability of the energy cycle is finally addressed, with specific reference to systems with high share of renewable energy and storage capability, highlighting some promising energy sources and storage approaches.
Towards criteria for sustainable process selection: On the modelling of pure subtractive versus additive/subtractive integrated manufacturing approac…
2017
Additive Manufacturing (AM) processes can be counted among the disruptive technologies that are capable of transforming conventional manufacturing routes. The ability to create complex geometries, the reduction in material scraps during manufacturing, and the light-weighting due to the think-additive redesign of the components represent the main points of strength of AM. However, for some applications (such as the production of metal components for the automotive and aerospace industries), the surface finishing and dimensional/geometrical part tolerancing that can be achieved via AM processes might not be adequate to satisfy the imposed product specifications, and finish machining operation…
A review of diagnostics and prognostics of low-speed machinery towards wind turbine farm-level health management
2016
Abstract Large wind farms are gaining prominence due to increasing dependence on renewable energy. In order to operate these wind farms reliably and efficiently, advanced maintenance strategies such as condition based maintenance are necessary. However, wind turbines pose unique challenges in terms of irregular load patterns, intermittent operation and harsh weather conditions, which have deterring effects on life of rotating machinery. This paper reviews the state-of-the-art in the area of diagnostics and prognostics pertaining to two critical failure prone components of wind turbines, namely, low-speed bearings and planetary gearboxes. The survey evaluates those methods that are applicabl…
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
2018
Background Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. NOTCH developmental signaling plays a critical role in promoting epithelial-to-mesenchymal transition, tumor stemness, and metastasis. Although all four NOTCH receptors show oncogenic properties, the unique role of each of these receptors in the sequential stepwise events that typify the invasion-metastasis cascade remains elusive. Methods We have established metastatic xenografts expressing high endogenous levels of NOTCH3 using estrogen receptor alpha-positive (ERα+) MCF…
Selection of a Sustainable Functional Pasta Enriched with Opuntia Using ELECTRE III Methodology
2017
In the last decade, the nutritional and health benefits of Opuntia (Opuntia ficus-indica (L.) Mill.) were discussed by academic scientists and private companies. In particular, the introduction of this substance in frequently consumed foods, like, for example, pasta and bakery products, could have a wide diffusion due to its rich composition in polyphenols, vitamins, polyunsaturated fatty acids, and amino acids. The identified natural cactus compounds are responsible for biologically relevant activities including anti-inflammatory, antioxidant, hypoglycemic, antimicrobial, and neuro-protective properties. The aim of this paper is the evaluation of the best combination of Opuntia quantity an…
Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation
2018
Somatic stem cells have been identified in multiple adult tissues. Whether self-renewal occurs symmetrically or asymmetrically is key to understanding long-term stem cell maintenance and generation of progeny for cell replacement. In the adult mouse brain, neural stem cells (NSCs) (B1 cells) are retained in the walls of the lateral ventricles (ventricular-subventricular zone [V-SVZ]). The mechanism of B1 cell retention into adulthood for lifelong neurogenesis is unknown. Using multiple clonal labeling techniques, we show that the vast majority of B1 cells divide symmetrically. Whereas 20%-30% symmetrically self-renew and can remain in the niche for several months before generating neurons, …
Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis
2020
International audience; Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the adult independently from monocytes. However, how they are maintained during non-alcoholic steatohepatitis (NASH) remains ill defined. We found that a fraction of KCs derived from Ly-6C+ monocytes during NASH, underlying impaired KC self-renewal. Monocyte-derived KCs (MoKCs) gradually seeded the KC pool as disease progressed in a response to embryo-derived KC (EmKC) death. Those MoKCs were partly immature and exhibited a pro-inflammatory status compared to EmKCs. Yet, they engrafted the KC pool for the long term as they remained following disease regression while acquiring matur…