Search results for " rene."

showing 10 items of 258 documents

MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer

2017

// Giuseppina Roscigno 1, 2, * , Ilaria Puoti 1, 2, * , Immacolata Giordano 1 , Elvira Donnarumma 3 , Valentina Russo 1 , Alessandra Affinito 1 , Assunta Adamo 1 , Cristina Quintavalle 1, 2 , Matilde Todaro 4 , Maria dM Vivanco 5 , Gerolama Condorelli 1, 2 1 Department of Molecular Medicine and Medical Biotechnology, “Federico II” University of Naples, Naples, Italy 2 IEOS, CNR, Naples, Italy 3 IRCCS-SDN, Naples, Italy 4 Department of Pathobiology and Medical Biotechnology, University of Palermo, Palermo, Italy 5 CIC bioGUNE, Centre for Cooperative Research in Biosciences, Derio, Spain * These authors have contributed equally to the paper as first authors Correspondence to: Gerolama Condore…

0301 basic medicinecancer stem cellsApoptosisStem cell markermedicine.disease_causemicroRNAs Breast cancer Cancer stem cells BimL FIH1Mixed Function OxygenasesAntineoplastic Agent0302 clinical medicineCell MovementTumor Cells CulturedCell Self RenewalMixed Function OxygenaseBimLmicroRNACell HypoxiamicroRNAsGene Expression Regulation NeoplasticOncology030220 oncology & carcinogenesisNeoplastic Stem CellsFemaleBreast NeoplasmAdult stem cellHumanResearch PaperFIH1BimL; FIH1; breast cancer; cancer stem cells; microRNAsAntineoplastic AgentsBreast Neoplasms03 medical and health sciencesBreast cancerbreast cancerDownregulation and upregulationCancer stem cellmicroRNAmedicineBiomarkers TumorHumansCell Proliferationbusiness.industryCancer stem cellApoptosiRepressor Proteinmedicine.diseaseHypoxia-Inducible Factor 1 alpha SubunitMolecular medicineRepressor Proteins030104 developmental biologyDrug Resistance NeoplasmImmunologyCancer researchNeoplastic Stem CellCisplatinCarcinogenesisbusiness
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Maristem stem cells of marine/aquatic invertebrates: from basic research to innovative applications

2018

The “stem cells” discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-type…

0301 basic medicinemarine/aquatic invertebratesQH301 Biologymarine/aquatic invertebrateBioactive moleculesT-NDASGeography Planning and Developmentlcsh:TJ807-830BiodiversitySettore BIO/05 - ZoologiaStem cellsblue biotechnology0302 clinical medicineBioactive moleculeBasic researchaging ; bioactive molecules ; blue biotechnology ; cancer ; cell culture ; COST Action ; Europe ; marine/aquatic invertebrates ; regeneration ; stem cellsGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)lcsh:Environmental sciencesCancerlcsh:GE1-350quinonessea-urchin eggsStem cellGeographyPolicy and LawEcologylcsh:Environmental effects of industries and plantsManagementEuropeMarine/aquatic invertebrateStem cellCèl·lules mareEuropean communityMonitoringaging; bioactive molecules; blue biotechnology; cancer; cell culture; COST Action; Europe; marine/aquatic invertebrates; regeneration; stem cellslcsh:Renewable energy sourcesCOST ActionAging; Bioactive molecules; Blue biotechnology; Cancer; Cell culture; COST Action; Europe; Marine/aquatic invertebrates; Regeneration; Stem cells; Geography Planning and Development; Renewable Energy Sustainability and the Environment; Management Monitoring Policy and LawManagement Monitoring Policy and LawBiologyQH30103 medical and health sciencesSDG 3 - Good Health and Well-beingNear neighborunitsstem cellsbioactive moleculesevolutioncancerSDG 14 - Life Below WaterRenewable Energy14. Life underwaterSH Aquaculture. Fisheries. AnglingSHRegeneration (ecology)BiologyBiomedicineInvertebratePlanning and Developmentcell cultureScience & TechnologySustainability and the EnvironmentRenewable Energy Sustainability and the Environmentbusiness.industryMarine invertebratesagingInvertebrats marinsbioactive moleculecell_developmental_biology030104 developmental biologylcsh:TD194-19513. Climate actionregenerationproteinbusiness030217 neurology & neurosurgery
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Assessment of genetically modified maize NK603 x MON810 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐007)

2018

Efsa Panel On Genetically Modified Organisms (gmo)Scientific opinionRequestor:European Commission (DG SANTE)Question number:EFSA-Q-2017-00028; Following the submission of application EFSA-GMO-RX-007 under Regulation (EC) No 1829/2003 from Monsanto, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of authorisation application of the herbicide-tolerant and insect-resistant genetically modified maize NK603 x MON810. The data received in the context of this renewal application contained post-market environmental monitoring reports, a systematic searc…

0301 basic medicinemaïsVeterinary (miscellaneous)gmo[SDV]Life Sciences [q-bio]2405 ParasitologyogmTP1-1185Plant SciencemaizeMicrobiologyzea mays03 medical and health sciences0404 agricultural biotechnology1110 Plant Sciencearticles 11 and 23TX341-6411106 Food ScienceNK603xMON8102. Zero hungerrenewal030109 nutrition & dieteticsNutrition. Foods and food supplymaize; NK603xMON810; renewal; articles 11 and 23; Regulation (EC) No1829/2003indian cornChemical technology2404 MicrobiologyRegulation (EC) No 1829/2003maize;NK603 x MON810;renewal;articles 11 and 23;Regulation (EC) No 1829/2003NK603 x MON81010079 Institute of Veterinary Pharmacology and Toxicology04 agricultural and veterinary sciences040401 food scienceSettore AGR/02 - Agronomia E Coltivazioni Erbacee3401 Veterinary (miscellaneous)Scientific OpinionSettore AGR/11 - Entomologia Generale E ApplicataRegulation (EC) No1829/2003570 Life sciences; biologyAnimal Science and ZoologyParasitology1103 Animal Science and ZoologyNK603 x MON810Regulation (EC) No 1829/2003Food Science
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Performance Study of Twisted Darrieus Hydrokinetic Turbine With Novel Blade Design

2021

Abstract Twisted Darrieus water turbine is receiving growing attention for small-scale hydropower generation. Accordingly, the need for raised water energy conversion incentivizes researchers to focus on the blade shape optimization of twisted Darrieus turbine. In view of this, experimental analysis has been performed to appraise the efficiency of a spiral Darrieus water rotor in the present work. To better the performance parameters of the studied water rotor with twisted blades, three novel blade shapes, namely U-shaped blade, V-shaped blade, and W-shaped blade, have been numerically tested using a computational fluid dynamics three-dimensional numerical model. The maximum power coefficie…

060102 archaeologyBlade (geometry)Renewable Energy Sustainability and the Environmentbusiness.industryTurbulence020209 energyMechanical EngineeringEnergy Engineering and Power Technology06 humanities and the arts02 engineering and technologyComputational fluid dynamicsTurbineSettore ICAR/01 - IdraulicaFuel TechnologyGeochemistry and Petrology0202 electrical engineering electronic engineering information engineeringEnvironmental science0601 history and archaeologybusinessalternative energy sources blade shape CFD efficiency energy extraction of energy from its natural resource flow characteristics power (co-) generation renewable energy twisted bladeHydraulic turbinesMarine engineeringJournal of Energy Resources Technology
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Dall?emergenza sanitaria all?emergenza economica: l?eccessiva onerosità sopravvenuta tra buona fede e obbligo di rinegoziazione.

2020

The paper focuses on the remedy of the rescission of the contract, underlining how the current situation of economic difficulty resulting from the pandemic, from a remedial point of view, finds in the good faith the most appropriate instrument for the protection of the contract.

:CIENCIAS JURÍDICAS [UNESCO]renegotiationgood faithUNESCO::CIENCIAS JURÍDICASCOVID-19COVID-19 rescission of contract good faith renegotiationrescission of contract
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Knockdown of NANOG Reduces Cell Proliferation and Induces G0/G1 Cell Cycle Arrest in Human Adipose Stem Cells

2019

The core components of regenerative medicine are stem cells with high self-renewal and tissue regeneration potentials. Adult stem cells can be obtained from many organs and tissues. NANOG, SOX2 and OCT4 represent the core regulatory network that suppresses differentiation-associated genes, maintaining the pluripotency of mesenchymal stem cells. The roles of NANOG in maintaining self-renewal and undifferentiated status of adult stem cells are still not perfectly established. In this study we define the effects of downregulation of NANOG in maintaining self-renewal and undifferentiated state in mesenchymal stem cells (MSCs) derived from subcutaneous adipose tissue (hASCs). hASCs were expanded…

AdultHomeobox protein NANOGDown-RegulationBiologyArticleCatalysisSettore MED/13 - Endocrinologialcsh:ChemistryInorganic ChemistrySOX2human adipose stem cellHumansCell Self RenewalPhysical and Theoretical Chemistrylcsh:QH301-705.5Molecular BiologyCells CulturedSpectroscopyCell Proliferationmolecular_biologyCell growthOrganic ChemistryMesenchymal stem cellDNMT1lentiviral transductionCell DifferentiationMesenchymal Stem CellsNanog Homeobox ProteinGeneral MedicineMiddle AgedCell cycleG1 Phase Cell Cycle CheckpointsComputer Science ApplicationsCell biologySettore MED/18 - Chirurgia GeneraleNANOGlcsh:Biology (General)lcsh:QD1-999Gene Knockdown Techniquesembryonic structures<i>NANOG</i>Female<i>DNMT1</i>CDKN1Bbiological phenomena cell phenomena and immunityStem cellcell cycle regulationAdult stem cell
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Le filiere del sistema agricolo per l'energia e l'efficienza energetica

2011

Increasing the use of renewable energies and Energy Efficiency offer significant opportunities for Italy to reduce fossil energy, greenhouse gas emissions and secure its energy supply. This report presents a brief analysis of the most important supply chains of the Agriculture system. Greatest attention is paid to the significant role that agriculture and its supply chains are likely to play in terms of bioenergy production and energy saving. Special attention is devoted to new agricultural activities like those associated with the reduction of vegetable food waste, the agrotourism, the urban agriculture, the plastic coverings and the greenhouses, the plant protection and the fertilizers. D…

Agriculture bioenergy efficiency renewable energy supply chain
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Effect of substrate improvement on optimising biogas yield from anaerobic digestion

2014

Masteroppgave i fornybar energi ENE 500 Universitetet i Agder 2014 The anaerobic digestion process involves the decomposition of the organic matter to yield biogas; gas that is mainly composed of methane and carbon dioxide with traces of some other gases. This process is used for different purposes including municipal waste treatment, wastewater treatment, fertilizer production, and farm wastes disposal as well as energy production. It is accomplished in three main stages; hydrolysis, acidogenesis and methanogenesis with each of the stages achieved by specific microorganisms that are active in limited ranges of operational and environmental conditions. These conditions are controlled to ach…

Anaerobic Digestion ; Biogas Yield ; Substrates ; Food wastes ; Fruit wastes ; Characterisation ; renewable energyENE500VDP::Technology: 500
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Counter-Clock World: How Planning Backwards Helps in Moving Forward in Collapsing Environments

2021

Research on corporate decline and turnarounds as well as the strategic use of history have so far remained two separate research fields. We integrate these two fields with a thought experiment, proposing ways in which strategists can work with, and through time in managing and turning around declines. Our thought experiment involves two very different types of analogies: a textual one from Philip K. Dick’s science fiction novels, on the one hand, and a visual one from Einsteinian relativity science, on the other hand. Inspired and informed by these different conceptualizations of the past and time, we develop four forms of backward strategizing to successfully manage a struggling corporatio…

Analogical reasoningThought experimentScience fictionuses of the pastHistorylcsh:Management. Industrial managementmenneisyysTemporalityStrategy and ManagementTemporalityhistory and temporalityAnalogical reasoninghistorialcsh:BusinessCorporationOrganizational decline and collapsescience fictionSociologyorganizational decline and collapsestrategic renewal and corporate turnaround managementUses of the pastStrategic optionsPerspective (graphical)CognitionMythologyhistoriatietoisuusGeneral Business Management and Accountinganalogical reasoningStrategic renewal and corporate turnaround managementyrityksetEpistemologylaskusuhdannelcsh:HD28-70uudistaminenstrateginen suunnittelutulevaisuuslcsh:HF5001-6182relativismitieteiskirjallisuusM@n@gement
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Short term wind speed prediction using Multi Layer Perceptron

2012

Among renewable energy sources wind energy is having an increasing influence on the supply of energy power. However wind energy is not a stationary power, depending on the fluctuations of the wind, so that is necessary to cope with these fluctuations that may cause problems the electricity grid stability. The ability to predict short-term wind speed and consequent production patterns becomes critical for the all the operators of wind energy. This paper studies several configurations of Artificial Neural Networks (ANN), a well-known tool able to estimate wind speed starting from measured data. The presented ANNs, t have been tested through data gathered in the area of Trapani (Sicily). Diffe…

Artificial neural networks Multi layer perceptron Feed forward network Forecasting Renewable energy Wind energy Wind speedSettore ING-IND/11 - Fisica Tecnica Ambientale
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