Search results for " rese"
showing 10 items of 14841 documents
'REOFUT' as an Observation Tool for Tactical Analysis on Offensive Performance in Soccer: Mixed Method Perspective
2019
Performance analysis in complex sports like soccer requires the study of the influence of the interaction between both teams during the game on final performance. The mixed methods approach involves the collection, analysis, and interpretation of qualitative and quantitative data for the same purpose and within the framework of the same study. To build certain observation tools, mixed methods are necessary in order to take advantage of integration between qualitative and quantitative elements. The aim of this study was to develop a new no standard observation tool to analyze soccer offensive performance considering not only the observed team but also some aspects of the opponent behavior, a…
Six-Week Endurance Exercise Alters Gut Metagenome That Is not Reflected in Systemic Metabolism in Over-weight Women.
2018
Recent studies suggest that exercise alters the gut microbiome. We determined whether six-weeks endurance exercise, without changing diet, affected the gut metagenome and systemic metabolites of overweight women. Previously sedentary overweight women (n = 19) underwent a six-weeks endurance exercise intervention, but two were excluded due to antibiotic therapy. The gut microbiota composition and functions were analyzed by 16S rRNA gene amplicon sequencing and metagenomics. Body composition was analyzed with DXA X-ray densitometer and serum metabolomics with NMR metabolomics. Total energy and energy-yielding nutrient intakes were analyzed from food records using Micro-Nutrica software. Serum…
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018…
2018
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean dia…
Strategic Design Towards Platform Collaboration in The Newspaper Industry: A Design Science Research Study
2020
The newspaper industry is challenged by unsustainable business models. To stabilize dwindling revenue streams, publishers opted for digital subscriptions as one avenue for generating additional revenue streams. Large publishers have indeed benefited from rising subscription numbers. However, smaller publishers are challenged to achieve the same results. Some of the root causes are high churn rates, adoption costs and lock-in effects of subscription services. News aggregator platforms may promise newspaper publishers a large pool of paying readers. But platform fees and the loss of direct customer relationships enact commercial barriers among publishers. This study proposes design science re…
Estudio de validación de los parámetros dinámicos de respuesta a fluidos, variación de volumen sistólico (VVS) y variación de presión de pulso (VPP),…
2021
Introducción En cirugía de resección pulmonar, se recomienda la fluidoterapia restrictiva debido al alto riesgo de lesión pulmonar aguda postresección atribuida al uso liberal de fluidos. Sin embargo, esta terapia puede dar lugar a hipoperfusión vascular y por tanto aumento de la morbimortalidad. La fluidoterapia intraoperatoria debe ser individualizada para cada paciente, ajustando el aporte o restricción de fluidos a fin de optimizar el gasto cardíaco y evitar lesiones en órganos vitales. La fluidoterapia guiada por objetivos permite realizar esta individualización de fluidos mediante el análisis de los parámetros VVS y VPP. El objetivo principal de este estudio es la validación de VVS y …
Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
2020
ABSTRACT Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeutic cancer vaccine, which is based on a liposomal formulation of tumor-antigen encoding RNA (RNA-LPX) and induces a strong T-cell response both in mice as well as in humans. In this study, we investigated in vivo in mice and in human PBMCs the effect of the commonly used long-acting GCS Dexamethasone (Dexa) on the efficacy of this vaccine format, with a particular focus on antigen-specif…
Transcranial Alternating Current Stimulation (tACS) Does Not Affect Sports People’s Explosive Power: A Pilot Study
2021
Purpose: This study is aimed to preliminary investigate whether transcranial alternating current stimulation (tACS) could affect explosive power considering genetic background in sport subjects.Methods: Seventeen healthy sports volunteers with at least 3 years of sports activities participated in the experiment. After 2 weeks of familiarization performed without any stimulation, each participant received either 50 Hz-tACS or sham-tACS. Before and after stimulation, subjects performed the following tests: (1) the squat jump with the hands on the hips (SJ); (2) countermovement jump with the hands on the hips (CMJ); (3) countermovement jump with arm swing (CMJ-AS); (4) 15-s Bosco’s test; (5) s…
Simultaneous optimization of harvest schedule and measurement strategy
2013
In many recent studies, the value of forest inventory information in the harvest scheduling has been examined. Usually only the profitability of measuring simultaneously all the stands in the area is examined. Yet, it may be more profitable to concentrate the measurement efforts to some subset of them. In this paper, the authors demonstrate that stochastic optimization can be used for defining the optimal measurement strategy simultaneously with the harvest decisions. The results show that without end-inventory constraints, it was most profitable to measure the stands that were just below the medium age. Measuring the oldest stands was not profitable at all. It turned out to be profitable t…
Design principles for collaboration platforms for open education
2015
Increasing the current low uptake of Open Education Resources (OER) is a key challenge for researchers and practitioners in the field. User studies have shown that collaboration is a main success factor for successful open educational activities. However, effective collaboration in open educational contexts requires well planned processes and platforms supporting collaboration, in particular in physically distributed settings. We have been investigating the value of such platforms, their main features and user requirements to enable collaboration from immature ideas to completed resources. We used quantitative and qualitative research methods to collect insights from potential users of such…
Wastewater treatment: New insight provided by interactive multiobjective optimization
2011
In this paper, we describe a new interactive tool developed for wastewater treatment plant design. The tool is aimed at supporting the designer in designing new wastewater treatment plants as well as optimizing the performance of already available plants. The idea is to utilize interactive multiobjective optimization which enables the designer to consider the design with respect to several conflicting evaluation criteria simultaneously. This is more important than ever because the requirements for wastewater treatment plants are getting tighter and tighter from both environmental and economical reasons. By combining a process simulator to simulate wastewater treatment and an interactive mul…