Search results for " restenosis"

showing 10 items of 31 documents

Intravascular Lithotripsy for Treatment of Calcified Lesions During Carotid Artery Stenting

2020

Purpose: To report the use of intravascular lithotripsy (IVL) in the treatment of calcified carotid artery lesions. Materials and Methods: The records of 21 high-surgical-risk patients (mean age 75.1±8.1 years; 17 men) who were treated at 8 centers for carotid artery stenosis ≥70% were retrospectively reviewed. Twelve patients had a history of cerebrovascular disease. All patients had heavily calcified carotid artery lesions: 19 de novo and 2 in-stent restenoses (ISR). The mean baseline stenosis was 82.3%±9.7%. IVL was utilized at the discretion of the operator, followed by balloon angioplasty. Embolic protection devices were used in all cases. Results: In 19 patients, IVL was followed by s…

Malemedicine.medical_specialtyCarotid arteriesmedicine.medical_treatmentLithotripsyLithotripsyCarotid artery diseaseHumansMedicineCarotid StenosisRadiology Nuclear Medicine and imagingVascular CalcificationAgedRetrospective StudiesAged 80 and overbusiness.industryMean agemedicine.diseaseArterial calcificationCarotid ArteriesTreatment OutcomeFemaleStentsSurgeryRadiologyIn stent restenosisCardiology and Cardiovascular MedicinebusinessAngioplasty BalloonJournal of Endovascular Therapy
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Sicilian DES Registry: prospective in-hospital and 9-month clinical and angiographic follow-up in selected high restenosis risk patients.

2008

OBJECTIVE: This is a multicentre, open label, prospective non-randomized registry, with 9-month angiographic follow-up, conducted to evaluate the safety and effectiveness of drug-eluting stents (DES) when used in high restenosis risk patients from the real world. METHODS: From June 2004 to February 2005, a total of 1622 consecutive patients were enrolled to the Sicilian DES Registry, according to specific inclusion criteria. Both paclitaxel-eluting and sirolimus-eluting stents were used. The analysis was performed on 1472 patients because 150 patients were excluded from the study. The primary endpoint was to evaluate the rate of major adverse cardiac events (MACE) within 9 months after DES …

Malemedicine.medical_specialtyPaclitaxelCoronary angioplastyRegistry.Target vessel revascularizationCoronary DiseaseCoronary AngiographyCoronary artery diseaseCoronary RestenosisRestenosisClinical endpointMedicineHumansCumulative incidencecardiovascular diseasesMyocardial infarctionDrug eluting stentRegistriesAngioplasty Balloon CoronarySicilyAgedSirolimusEjection fractionbusiness.industryIncidence (epidemiology)Drug-Eluting StentsGeneral MedicineMiddle Agedmedicine.diseaseSurgeryFemaleCardiology and Cardiovascular MedicinebusinessMaceDiabetic AngiopathiesImmunosuppressive AgentsJournal of cardiovascular medicine (Hagerstown, Md.)
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A novel 3-d reconstruction system for the assessment of bifurcation lesions treated by the mini-crush technique.

2010

Background: Conventional two-dimensional angiography lacks the ability to properly image the true bifurcation geometry, and its percutaneous coronary intervention-induced changes in the clinical setting. Methods and Results: A novel three-dimensional reconstruction system was investigated by retrospectively analyzing 39 lesions in 35 consecutive patients with coronary bifurcation disease treated with the mini-crush technique. At baseline, significant correlations were proved between two- and three-dimensional systems in terms of either reference vessel diameter (R 2 = 0.68 and 0.29 for main and side branches, respectively), minimum lumen diameter (R 2 = 0.73 and 0.36), stenosis diameter (R …

Malemedicine.medical_specialtyPercutaneousTime Factorsmedicine.medical_treatmentStatistics as TopicCoronary Artery DiseaseCoronary AngiographyStatistics NonparametricVentricular Function LeftLesionCoronary RestenosisImaging Three-DimensionalmedicineHumansRadiology Nuclear Medicine and imagingAngioplasty Balloon CoronaryCoronary Artery BypassBifurcationRetrospective StudiesAnalysis of Variancemedicine.diagnostic_testMini-Crush Technique.business.industryStentStroke VolumeMiddle Agedmedicine.diseaseCoronary VesselsLumen DiameterVessel diameterStenosisAngiographyBifurcationFemaleRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessAlgorithmsSoftwareJournal of interventional cardiology
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9-Month Clinical and Angiographic Outcomes of the COBRA Polyzene-F NanoCoated Coronary Stent System

2016

Abstract Objectives The aim of this study was to assess the safety and effectiveness of the COBRA Polyzene-F NanoCoated Coronary Stent System (CeloNova Biosciences, San Antonio, Texas) for the treatment of de novo coronary artery lesions. Background Polyzene-F–coated coronary stents have shown reduced thrombogenicity and inflammation in preclinical studies. Methods Patients with de novo coronary artery lesions meeting eligibility criteria were enrolled in a nonrandomized, prospective clinical trial. The primary endpoint was target vessel failure (TVF) (defined as a composite of cardiac death, myocardial infarction, or clinically driven target vessel revascularization) at 9 months. A pre-spe…

Malemedicine.medical_specialtyTime FactorsPolymersmedicine.medical_treatmentCoronary Artery Disease030204 cardiovascular system & hematologyCoronary AngiographyProsthesis DesignCoronary RestenosisCoronary artery disease03 medical and health sciencesOrganophosphorus Compounds0302 clinical medicineCoated Materials BiocompatibleCoronary thrombosisRestenosisPredictive Value of TestsRisk FactorsInternal medicineAngioplastyCoronary stentmedicineClinical endpointHumansProspective Studies030212 general & internal medicineMyocardial infarctionAngioplasty Balloon CoronaryAgedbusiness.industryCoronary ThrombosisStentMiddle Agedmedicine.diseaseCoronary VesselsSurgeryTreatment OutcomeCardiologyNanoparticlesFemaleStentsCardiology and Cardiovascular MedicinebusinessJACC: Cardiovascular Interventions
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Optical Coherence Tomography Versus Intravascular Ultrasound to Evaluate Coronary Artery Disease and Percutaneous Coronary Intervention

2013

ObjectivesWe compared intravascular ultrasound (IVUS) and 2 different generations of optical coherence tomography (OCT)—time-domain OCT (TD-OCT) and frequency-domain OCT (FD-OCT)—for the assessment of coronary disease and percutaneous coronary intervention (PCI) using stents.BackgroundOCT is a promising light-based intravascular imaging modality with higher resolution than IVUS. However, the paucity of data on OCT image quantification has limited its application in clinical practice.MethodsA total of 227 matched OCT and IVUS pull backs were studied. One hundred FD-OCT and IVUS pull backs in nonstented (n = 56) and stented (n = 44) vessels were compared. Additionally, 127 matched TD-OCT and …

Malemedicine.medical_specialtyTime Factorsgenetic structuresmedicine.medical_treatmentTreatment outcomeSeverity of Illness Indexintravascular ultrasoundCoronary RestenosisCoronary artery diseaseOptical coherence tomographyPredictive Value of TestsNeointimaIntravascular ultrasoundmedicineHumanscardiovascular diseasesUltrasonography InterventionalAgedCell ProliferationAnalysis of VarianceHyperplasiaoptical coherence tomographymedicine.diagnostic_testbusiness.industrypercutaneous coronary interventionCoronary StenosisPercutaneous coronary interventionMiddle Agedequipment and suppliesmedicine.diseaseCoronary Vesselseye diseasesTreatment Outcomesurgical procedures operativeLinear ModelsFemaleStentssense organsTomographyRadiologyUltrasonographybusinessCardiology and Cardiovascular MedicineTomography Optical CoherenceJACC: Cardiovascular Interventions
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Real world safety and efficacy of the Janus Tacrolimus-Eluting stent: long-term clinical outcome and angiographic findings from the Tacrolimus-Elutin…

2009

Objectives: We sought to evaluate the safety and performance of the Janus Tacrolimus-Eluting stent (TES) in an unselected population of patients, without application of restrictive clinical or angiographic criteria. Background: Continued attention to the safety, efficacy, and deliverability of first-generation drug eluting stents has led to the development of new antiproliferative agents with alternative stent platforms and different drug carrier vehicles. Methods: The TEST (Tacrolimus Eluting STent) registry is a prospective, nonrandomized single-center registry in which 140 consecutive patients who underwent single- or multi-vessel percutaneous coronary intervention between February 2005 …

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentPopulationMyocardial InfarctionRestenosiKaplan-Meier EstimateCoronary AngiographyProsthesis DesignRisk AssessmentTacrolimusCoronary RestenosisRestenosismedicineHumansRadiology Nuclear Medicine and imagingMyocardial infarctionProspective StudiesRegistriesAngioplasty Balloon CoronaryeducationAgededucation.field_of_studybusiness.industryCoronary StenosisStentPercutaneous coronary interventionTacrolimus eluting stent.Cardiovascular AgentsDrug-Eluting StentsGeneral MedicineMiddle Agedmedicine.diseaseTacrolimusSurgeryTreatment OutcomeAntiproliferative AgentsFemaleRadiologySafetyCardiology and Cardiovascular MedicinebusinessMaceCatheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions
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Feasibility of Implanting 50-60 mm-Tapered Drug Eluting Stents in Chronic Total Occlusions.

2018

Abstract Background Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) usually involves multiple overlapping stents implantation to cover long coronary segments. A higher rate of restenosis has been described with stent overlapping. Recently, new long tapered stents emerged as a potential tool for treating long coronary lesions. Feasibility of using these new devices for the CTO PCI has not been described. The aim of this work was to describe our initial experience with 50 and 60 mm-long tapered sirolimus-eluting stents (SES) in CTO PCI. Methods We included 54 consecutive patients who underwent a CTO PCI and in whom an attempt to implant a 50 or 60 mm-long tapered SE…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentTarget vessel030204 cardiovascular system & hematologyProsthesis DesignCoronary Restenosis03 medical and health sciences0302 clinical medicinePercutaneous Coronary InterventionRestenosismedicineHumanscardiovascular diseases030212 general & internal medicineVascular PatencyAgedRetrospective StudiesSirolimusbusiness.industryPercutaneous coronary interventionStentCardiovascular AgentsDrug-Eluting StentsGeneral MedicineMiddle Agedmedicine.diseaseSurgerysurgical procedures operativeTreatment OutcomeCoronary OcclusionConventional PCIChronic DiseaseFeasibility StudiesFemaleImplantCardiology and Cardiovascular MedicinebusinessCardiovascular revascularization medicine : including molecular interventions
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Bioresorbable vascular scaffold versus everolimus-eluting stents or drug eluting balloon for the treatment of coronary in-stent restenosis: 1-Year fo…

2017

Objectives to compare the 1-year outcome between bioresorbable vascular scaffold (BVS), everolimus-eluting stent (EES), and drug-eluting balloon (DEB) for in-stent restenosis (ISR) treatment. Background BVS has been proposed as alternative for ISR treatment. To date a direct comparison between BVS and DES or DEB for ISR treatment is lacking. Methods We retrospectively analyzed all ISR lesions treated with BVS, DEB, and EES from January 2012 to December 2014. A total of 548 lesions (498 patients) were included. By applying two propensity-score matching, 93 lesions treated with BVS were compared with 93 lesions treated with DEB, and 100 lesions treated with BVS were compared to 100 lesions tr…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentUrology030204 cardiovascular system & hematologyProsthesis DesignBalloonRisk AssessmentCardiac CathetersCoronary Restenosis03 medical and health sciences0302 clinical medicineCoated Materials BiocompatibleRestenosisRisk FactorsAbsorbable ImplantsmedicineHumansRadiology Nuclear Medicine and imagingEverolimus030212 general & internal medicineAngioplasty Balloon CoronaryPropensity ScoreAgedRetrospective StudiesBioresorbable vascular scaffoldin stent restenosibusiness.industryIncidence (epidemiology)percutaneous coronary interventionStentPercutaneous coronary interventionCardiovascular AgentsDrug-Eluting StentsGeneral MedicineMiddle Agedmedicine.diseaseTreatment OutcomeItalyDrug-eluting stentPropensity score matchingFemalebioresorbable vascular scaffolddrug eluting balloonCardiology and Cardiovascular Medicinebusinessdrug eluting stent
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Peripheral atherosclerosis is associated with the occurrence of restenosis after percutaneous coronary intervention

2007

The aim of our study was to evaluate, in patients with proven coronary artery disease (CAD) and treated with elective percutaneous coronary intervention (PCI), whether the coexistence of asymptomatic carotid and femoral atherosclerotic lesions would provide prognostic information in terms of occurrence of restenosis.We studied 104 patients with CAD (M/F=77/27), mean age 60.5+/-9 years. All patients were treated with elective PCI. After PCI the suspicion of restenosis was confirmed by coronary angiography. All patients underwent ultrasound duplex scan of carotid and femoral-popliteal-tibial axis to detect atherosclerotic lesions. According to ultrasound results, patients were classified as n…

Malemedicine.medical_specialtymedicine.medical_treatmentBalloonAsymptomaticPeripheral atherosclerosispercutaneous coronary interventionCoronary RestenosisCoronary artery diseaseRestenosisInternal medicineAngioplastymedicineHumanscardiovascular diseasesAngioplasty Balloon CoronaryAgedPeripheral Vascular Diseasesbusiness.industryPercutaneous coronary interventionGeneral MedicineMiddle AgedAtherosclerosisPrognosismedicine.diseasePeripheralConventional PCICardiologyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessCoronary Artery Disease
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Diagnostic accuracy of 64-slice CT in the assessment of coronary stents

2007

PURPOSE: The purpose of this study was to assess the diagnostic accuracy of 64-slice computed tomography (64-CT) coronary angiography in the detection of coronary in-stent restenosis. MATERIALS AND METHODS: Ninety-five patients (72 men and 23 women, mean age 58+/-8 years) with previous percutaneous coronary intervention with stenting and suspected restenosis underwent 64-CT (Sensation 64, Siemens). The mean time between stent deployment and 64-CT was 6.1+/-4.2 months. The scan parameters were: slices 32 x 2, individual detector width 0.6 mm, rotation time 0.33 s, feed 3.84 mm/rotation, 120 kV, 900 mAs. After the intravenous administration of iodinated contrast material (Iomeprol 400 mgI/ml,…

Malemedicine.medical_specialtymedicine.medical_treatmentCoronary AngiographyCoronary RestenosisRestenosisIodinated contrastcoronary stentsHumansMedicineRadiology Nuclear Medicine and imagingSalineNeuroradiologymedicine.diagnostic_testbusiness.industryUltrasoundReproducibility of ResultsPercutaneous coronary interventionInterventional radiologyGeneral MedicineMiddle Agedmedicine.diseaseFemaleStentsRadiologyBolus (digestion)Tomography X-Ray ComputedbusinessRadiologia Medica
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