Search results for " rete"

showing 10 items of 346 documents

Water retention and swelling behaviour of granular bentonites for application in Geosynthetic Clay Liner (GCL) systems

2016

Geosynthetic Clay Liner (GCL) systems are used as efficient hydraulic barriers in landfills for the disposal of hazardous municipal wastes. Along with geotextiles, bentonite materials are chosen as one of the primary components of GCLs due to their high retention, adsorption, and swelling capacities. GCLs are manufactured using bentonites at a high total suction and hydrated through the uptake of liquid from the subsoil and the confined material as soon as they are installed. Bentonites may exhibit considerable volume change upon wetting. Depending on the confinement stress, the void ratio may significantly increase with a decrease in suction, particularly at higher degrees of saturation. T…

021110 strategic defence & security studiesMaterials science0211 other engineering and technologies02 engineering and technologyGeotechnical Engineering and Engineering GeologyGeosynthetic Clay LinersGeosynthetic Clay LinerWater retentionGranular bentoniteVoid ratioHydraulic conductivityGeosynthetic clay linerBentoniteParticle-size distributionmedicineGeotechnical engineeringWater retention behaviourSwellingmedicine.symptomHydrated void ratioSaturation (chemistry)Swelling potential021101 geological & geomatics engineeringCivil and Structural Engineering
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Experimental study of a naturally weathered stiff clay

2016

Studying the shear strength of a naturally weathered clay is important to understand rain-induced slope failures in weathered soils. However, experimental studies on naturally weathered soils are limited. The paper focuses on the laboratory experimental investigation carried out to analyse the shear strength of a naturally weathered stiff clay that can be found in unsaturated conditions in situ. This has an important practical relevance in the evaluation of the stability conditions of natural slopes at clay outcrops. Different experimental techniques of suction measurement were used to obtain the soil-water retention curve of the clay over a wide range of suctions. Scanning electronic micr…

021110 strategic defence & security studiesNaturally weathered clayUnsaturated undisturbed clayExpansive clayIsotropy0211 other engineering and technologiesMineralogy02 engineering and technologyGeotechnical Engineering and Engineering Geologycomplex mixturesnaturally weathered clay unsaturated undisturbed clay water retention behaviour shear strengthShear (geology)Shear strengthSoil waterGeotechnical engineeringWater retention behaviourMercury intrusion porosimetryTriaxial compressionGeology021101 geological & geomatics engineeringCivil and Structural Engineering
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Anakinra drug retention rate and predictive factors of long-term response in systemic juvenile idiopathic arthritis and adult onset still disease

2019

Background and Objective: Only a few studies have reported long-term efficacy of interleukin (IL)-1 inhibition in systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still disease (AOSD). Herein we report on the effectiveness of anakinra (ANA), expressed in terms of drug retention rate (DRR), and evaluate the predictive factors of drug survival in a cohort of patients with sJIA and AOSD. Patients and Methods: This is a multicenter study reviewing retrospectively the medical records from 61 patients with sJIA and 76 with AOSD, all treated with ANA in 25 Italian tertiary referral centers. Results: The cumulative retention rate of ANA at 12-, 24-, 48-, and 60-month of follow-up was 7…

0301 basic medicineAdult onset Still diseasemedicine.medical_specialtyArthritisStill DiseaseAdult onset Still disease; Anakinra; Drug retention rate; Innovative biotechnologies; Interleukin 1-beta; Personalized medicine; Systemic juvenile idiopathic arthritis03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E Specialisticaanakinra interleukin 1-beta innovative biotechnologies drug retention rate systemic juvenile idiopathic arthritis adult onset Still disease personalized medicineSystemic juvenile idiopathic arthritisInternal medicinemedicinePharmacology (medical)Adverse effectOriginal ResearchPharmacologyAnakinrabusiness.industryHazard ratiolcsh:RM1-950Innovative biotechnologiesmedicine.diseaseDrug retention ratePersonalized medicineConfidence intervalAdult onset Still disease Anakinra Drug retention rate Innovative biotechnologies Interleukin 1-beta Personalized medicine Systemic juvenile idiopathic arthritisDiscontinuation030104 developmental biologylcsh:Therapeutics. PharmacologyAnakinraInnovative biotechnologie030220 oncology & carcinogenesisCohortInterleukin 1-betabusinessmedicine.drug
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Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis.

2019

Introduction: The advent of biologic agents has revolutionized therapeutic approaches in systemic juvenile idiopatic arthritis (sJIA) as their introduction has been shown to modify disease course and improve overall outcomes, particularly when initiated early. Few studies have reported the drug retention rate (DRR) of biologic drugs in JIA, and none of them has specifically investigated the DRR of interleukin (IL)-1 inhibitors on sJIA. Objectives: The primary aim of the study was to examine the overall DRR of IL-1 blockers in sJIA patients. Secondary aims of our study were to: (i) explore the influence of biologic line of treatment, adverse events (AEs), type of anti-IL-1 agent and the conc…

0301 basic medicineDrugmedicine.medical_specialtysystemic juvenile idiopathic arthritismedia_common.quotation_subjectArthritisanakinra; canakinumab; drug retention rate; interleukin 1-beta; systemic juvenile idiopathic arthritis; therapycanakinumab03 medical and health sciencesSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicineInterleukin-1 inhibitors Systemic Juvenile Idiopathic Arthritis Anakinra CanakinumabInternal medicineinterleukin 1-betaMedicinePharmacology (medical)Adverse effectmedia_commonOriginal ResearchPharmacologyAnakinraAnakinra Canakinumab Drug retention rate Interleukin 1-beta Systemic juvenile idiopathic arthritis Therapytherapybusiness.industrylcsh:RM1-950Hazard ratioInterleukinJuvenile idiopathic arthritisRetention ratemedicine.diseaseCanakinumablcsh:Therapeutics. Pharmacology030104 developmental biology030220 oncology & carcinogenesisSystemic juvenile idiopathic arthritidrug retention ratebusinessmedicine.druganakinraFrontiers in pharmacology
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Understanding the performance of an AnMBR treating urban wastewater and food waste via model simulation and characterization of the microbial populat…

2018

[EN] An anaerobic membrane bioreactor (AnMBR) pilot plant treating kitchen food waste (FW) jointly with urban wastewater was run for 536 days. Different operational conditions were tested varying the sludge retention time (SRT), the hydraulic retention time (HRT) and the penetration factor (PF) of food waste disposers. COD removal efficiency exceeded 90% in all tested conditions. The joint treatment resulted in an almost 3-fold increase in methane production (at 70 days of SRT, 24 h HRT and 80% PF) in comparison with the treatment of urban wastewater only. Mathematical model simulations and Illumina technology were used to obtain in-depth information of this outstanding process performance.…

0301 basic medicineHydraulic retention timePopulationBioengineering010501 environmental sciences01 natural sciencesApplied Microbiology and BiotechnologyBiochemistry03 medical and health scienceseducationTECNOLOGIA DEL MEDIO AMBIENTE0105 earth and related environmental sciencesResource recoveryeducation.field_of_studyFood wasteResource recoveryBiodegradationPulp and paper industryFood waste030104 developmental biologyPilot plantAnMBRWastewaterEnvironmental scienceFermentationSimulation
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Virological response and retention in care according to time of starting ART in Italy: data from the Icona Foundation Study cohort

2020

Abstract Objectives To describe: (i) factors associated with rapid and delayed ART initiation; (ii) rates of 12 week virological response; and (iii) virologically controlled retention in care by 1 year from ART initiation according to timing of start in a real-life setting. Methods All individuals in the Icona cohort diagnosed with HIV in 2016–17 who initiated ART were grouped according to the time between HIV diagnosis and ART initiation: Group 1, ≤7 days; Group 2, 8–14 days; Group 3, 15–30 days; Group 4, 31–120 days; and Group 5, >120 days. Multivariable logistic regression models were used to identify factors associated with: (i) the probability of rapid (Group 1) and very delayed…

0301 basic medicinediagnosishivcommunicable diseasesHIV InfectionsLogistic regressionVirological responseCohort Studies0302 clinical medicineRetention in CareMedicinePharmacology (medical)HIV Infection030212 general & internal medicineProspective cohort studycd4 count determination proceduredrugsuppressionViral LoadCD4 Lymphocyte Count; Cohort Studies; Humans; Italy; Viral Load; Anti-HIV Agents; HIV Infections; Retention in CarevirologyInfectious DiseasesItalyblood hiv rnaCohorthiv cd4 count determination procedure communicable diseases incomeitaly diagnosis virology blood hiv rna retention in careincomeitalyViral loadHIV ARTCohort studyHumanMicrobiology (medical)medicine.medical_specialtyAnti-HIV Agentsantiretroviral therapySettore MED/17 - MALATTIE INFETTIVENO03 medical and health sciencesHIV viral loadInternal medicineHumansHIV CD4 ARTPharmacologybusiness.industrydouble blindAnti-HIV AgentHIV viral load antiretroviral therapy double blind initiation suppression infectionRetention in care030112 virologyinfectioninitiationCD4 Lymphocyte CountObservational studyCohort Studiebusiness
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The Influence of Retention, Turnover, and Alliance on Process and Outcomes in Rolling Group Psychotherapy for Cocaine Disorder

2016

ABSTRACTA longitudinal repeated measures design was used to investigate the influence of treatment retention, and membership turnover on individual outcomes, and the relationship between individual-level and group-level therapeutic alliance in rolling group psychotherapy for individuals with cocaine abuse disorder. Eighteen patients were studied; data were collected prior to therapy and then monthly for 24 months. Patient outcomes and process were assessed. Improvements in symptoms and psychological functioning were associated with retention in psychotherapy. Membership turnover had a negative influence on symptoms. Development of an individual alliance was affected by the development of gr…

050103 clinical psychologymedicine.medical_specialtyretentionmedicine.medical_treatment05 social sciences030508 substance abuseRepeated measures designTreatment retentionGroup psychotherapy03 medical and health sciencesClinical PsychologyAllianceGroup psychotherapySettore M-PSI/08 - Psicologia Clinicamedicine0501 psychology and cognitive sciencescocaine disorder0305 other medical sciencePsychiatryPsychologyCocaine abuseClinical psychology
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Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation.

2017

Abstract In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer, named PHEA-BIB-ButMA (PBB), was synthesized by Atom Trasnfer Radical Polymerization (ATRP) starting from the α-poly( N -2-hydroxyethyl)- d , l -aspartamide (PHEA) and poly butyl methacrylate (ButMA). Empty and sorafenib loaded PBB NPs were, then, produced by using a dialysis method and showed spherical morphology, colloidal size, negative ζ potential and the ability to allow a sustained sorafenib release in physiological environment. Sorafenib loaded PBB NPs were tested in vitro on HCC cells in order to e…

3003MaleHepatocellular carcinomamedicine.medical_treatmentPharmaceutical Science02 engineering and technologyATRPPharmacology01 natural sciencesDrug Delivery SystemsCopolymerChemistryATRP; Hepatocellular carcinoma; Sorafenib; Tumor targeting; α-Poly(N-2-hydroxyethyl)-DL-aspartamide; 3003Liver NeoplasmsSorafenib021001 nanoscience & nanotechnologyDrug delivery0210 nano-technologymedicine.drugSorafenibNiacinamideCarcinoma HepatocellularCell SurvivalRadical polymerizationIntraperitoneal injectionL-aspartamideMice NudeAntineoplastic AgentsEnhanced permeability and retention effect010402 general chemistryPolymethacrylic AcidsIn vivoCell Line TumormedicineAnimalsHumansneoplasmsProtein Kinase InhibitorsPhenylurea Compoundstechnology industry and agriculturedigestive system diseasesIn vitro0104 chemical sciencesDrug LiberationTumor targetingDelayed-Action PreparationsBiophysicsα-Poly(N-2-hydroxyethyl)-DNanoparticlesα-Poly(N-2-hydroxyethyl)-DL-aspartamidePeptidesJournal of controlled release : official journal of the Controlled Release Society
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Retención a los 6 años en un programa de mantenimiento con metadona y variables relacionadas

2001

Objetivos: conocer la retención en un PMM a los 6 años de una población de heroinóma¬nos de larga evolución y las variables relacionadas con una mayor adherencia.Pacientes, material y métodos: se estudiaron 132 dependientes de opiáceos que comenza¬ron un PMM entre 1991-92. Se les administró un protocolo "ad hoc" recogiendo varia¬bles sociodemográficas y clínicas. Se calculó la retención en tratamiento mediante análisis de supervivencia de Kaplan-Mayer y se buscaron las variables relacionadas con ella.Resultados: el perfil de los estudiados era el de un heroinómano de larga evolución con severos problemas médicos y sociales. La retención ajustada fue del 70,1% a los seis años. Las pérdidas s…

:PSICOLOGÍA::Psicofarmacología [UNESCO]:PSICOLOGÍA [UNESCO]Mantenimiento con metadona Retención Dosis VIH Efectividad.UNESCO::PSICOLOGÍAUNESCO::PSICOLOGÍA::Psicofarmacología
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Mismos caminos, distintos destinos. Explorando el efecto de las trayectorias educativas y del origen social en las transiciones hacia la educación po…

2020

Las transiciones a la educación postobligatoria son un elemento clave para comprender las desigualdades educativas y sociales. La elección de los estudios postobligatorios por parte de los y las jóvenes está mediada por patrones de desigualdad social, así como por sus trayectorias y experiencias escolares previas. Partiendo de este marco, este artículo responde al objetivo de comprender de qué forma las trayectorias escolares de los y las jóvenes en la etapa de la educación obligatoria contribuyen a explicar sus elecciones acerca del itinerario postobligatorio. Más allá de un análisis que incorpore los factores descriptivos de las trayectorias escolares -como la repetición de curso o el ren…

Academic yearmedia_common.quotation_subjectPedagogyRhetoricUNESCO::SOCIOLOGÍAGeneral EngineeringSocial inequalitySociologyGrade retentionFactorial analysisCompulsory education:SOCIOLOGÍA [UNESCO]media_common
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