Search results for " ruthenium"

showing 6 items of 16 documents

Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric App…

2017

We report here on the synthesis of a series of mono-and dinuclear gold(I) complexes exhibiting sulfonated bis(NHC) ligands and novel hydroxylated mono(NHC) Au(I) compounds, which were also examined for their 'biological activities. Initial cell viability assays show strong antiproliferative activities of the hydroxylated mono(NHC) gold compounds (8 > 9 > 10) against 2008 human ovarian cancer cells even after 1 h incubation. In order to gain insight into the mechanism of biological action of the gold compounds, their effect on the pivotal cellular target seleno-enzyme thioredoxin reductase (TrxR), involved in the maintenance of intracellular redox balance, was investigated in depth. Th…

Thioredoxin Reductase 1AuranofinSilverStereochemistryThioredoxin reductaseThioredoxin Reductase 2WATER-SOLUBLE RUTHENIUM(II)Antineoplastic Agents010402 general chemistryG-quadruplexLigandsIN-VITRO CYTOTOXICITYLIGANDS SYNTHESIS01 natural sciencesInorganic Chemistrychemistry.chemical_compoundDrug StabilityThioredoxin Reductase 1Coordination ComplexesTHIOREDOXIN REDUCTASE INHIBITIONCell Line TumormedicineOrganogold CompoundsAnimalsHumansCRYSTAL-STRUCTURESPhysical and Theoretical ChemistryCANCER CELLSBIOLOGICAL-PROPERTIES010405 organic chemistryChemistryMOLECULAR-MECHANISMSDNA0104 chemical sciencesRatsG-QuadruplexesGlutathione ReductaseSolubilityBiological targetCancer cellPLATINUM ANTICANCER DRUGSMETAL-COMPLEXESGoldReactive Oxygen SpeciesCarbeneHydrophobic and Hydrophilic InteractionsOrganogold Compoundsmedicine.drugInorganic Chemistry
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Elaboration and interfacial reactivity of Lanthanum Strontium Chromium Ruthenium (LSCrRu) perovskite oxides as intermediate temperature fuel cell (IT…

2005

New data on the interest of ruthenium doped lanthanum strontium chromite La1-xSrxCr1-yRuyO3δ (LSCrRu) as anode in ITSOFC are presented. Microwave synthesis of mixed oxides allowed shaping of half-cells and complete cells using sputtering and screen printing methods. LSCrRu methane reforming property had been studied in a mono-chamber system coupled with a mass spectrometer in collaboration with Institut de REcherche Hydro-Québec. Anode/electrolyte interfacial reactivity had been analysed using SIMS and XRD on half cells models after ageing under H2 at 800°C. This experiment gave the chemical composition of the film after treatment. Complete cells, tested under working conditions, highlight…

[CHIM.MATE] Chemical Sciences/Material chemistryreformage interneinterface anode/électrolyteChromite de lanthane strontium dopé au rutheniumsynthèse micro-onde[ CHIM.MATE ] Chemical Sciences/Material chemistrypiles à combustible ITSOFC[CHIM.MATE]Chemical Sciences/Material chemistrypulvérisation cathodiquemono-chambreréactivité
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Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand

2019

Abstract Three heterobimetallic platinum (II)/ruthenium (II) and platinum (II)/rhodium (III) complexes, A: Pt{S–S2C2(NR)2H}{μ-S2C2(NR)2}-[Ru (p-cymene)Cl], R = isoamyl; B: Pt{S–S2C2(NR)2H}{μ-S2C2(NR)2}[Rh (phpy)2], R = isoamyl; C: [Pt{S–S2C2(NR)2H}{μ-S2C2(NR)2}-[Rh(C5Me5)Cl]], R = benzyl, were prepared from mononuclear complexes 1 and 2, 1: [Pt (H-isoamyl2DTO)2]; 2: [Pt (H-benzyl2DTO)2], DTO = dithiooxamide, by reaction of 1 or 2 with the corresponding chlorido-bridged dimers, [Rh(C5Me5)Cl (μ-Cl)]2, [Ru (p-cymene)Cl (μ-Cl)]2 or [Rh (phpy)2 (μ-Cl)]2, and then evaluated as anticancer agents for the inhibition of the three proteolytic activities of human 20S proteasome, one of the main target …

chemistry.chemical_classification010405 organic chemistryChemistryOrganic Chemistrychemistry.chemical_element010402 general chemistrymedicine.disease01 natural sciencesBiochemistryMedicinal chemistry0104 chemical sciencesRhodiumRutheniumAnticancer; Dithiooxamide; Heterobimetallic; Platinum complexes; Rhodium; RutheniumInorganic Chemistrychemistry.chemical_compoundEnzymeDithiooxamideApoptosisNeuroblastomaMaterials ChemistrymedicinePhysical and Theoretical ChemistryPlatinumCytotoxicityJournal of Organometallic Chemistry
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l-Arabinose Conformers Adsorption on Ruthenium Surfaces: A DFT Study

2012

Adsorption of 5 L-arabinose tautomers – one acyclic and four cyclic (α and β, pyranose and furanose) species – on a ruthenium surface was studied as a precursor-process of the, nowadays more and more, industrially important sugar catalytic hydrogenation on metal surfaces in water medium. The study was mostly referred to a 37-atom metal catalyst fragment, even though border-effects on the adsorption processes were also checked employing a 61-atom metal fragment. In order to figure out conformational effects on the title process the tautomer flexibility was, at first, investigated by the genetic-algorithm based code Balloon, considering the conformational spaces of the different aquo tautomer…

chemistry.chemical_element02 engineering and technology010402 general chemistry01 natural sciencesMetalAdsorptionComputational chemistryPhysical and Theoretical Chemistryl-Arabinose species conformational analysis ruthenium catalysts adsorption energies DFT studiesConformational isomerismchemistry.chemical_classification021001 nanoscience & nanotechnologyFuranoseTautomer0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsRutheniumGeneral EnergyPyranosechemistrySettore CHIM/03 - Chimica Generale E Inorganicavisual_artvisual_art.visual_art_mediumDensity functional theory0210 nano-technologyThe Journal of Physical Chemistry C
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Characterization of Ruthenium-based Dye-Sensitized solar cells

2015

In this paper, we measure the main photoelectrical parameters of Dye Sensitized Solar Cells (DSSCs) based on ruthenium complexes at different irradiance levels, incident wavelengths, temperatures and hours of light soaking.

solar cell dssc ruthenium solar cellsSettore ING-INF/02 - Campi ElettromagneticiSettore ING-INF/01 - Elettronica
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Nanostructured Material Fabrication for Energy Conversion

2010

tin alloy ruthenium oxide palladium cobalt alloy lithium ion battery electrolyzersSettore ING-IND/23 - Chimica Fisica Applicata
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