Search results for " sample"

showing 10 items of 456 documents

In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

In situPO Propylene oxideIV IntravenousP338 Poloxamer 338lcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_compoundn Sample sizeSD Standard deviationIM Intramuscularchemistry.chemical_classificationC0 Analyte plasma concentration at time zeroDoE Design of experimentsUV UltravioletPharmacology. TherapyK2.EDTA Potassium ethylenediaminetetraacetic acidLC–MS/MS Liquid chromatography-tandem mass spectrometryH&E Hematoxylin and eosintmax Sampling time to reach the maximum observed analyte plasma concentrationIn situ forming gelsCMC Critical micellar concentrationCmax Maximum observed analyte plasma concentrationIntramuscular injectionDN Dose normalizedGPT Gel point temperaturePLGA Poly-(DL-lactic-co-glycolic acid)TFA Trifluoroacetic acidCAN AcetonitrileATP Adenosine 5′ triphosphateSalt (chemistry)Polyethylene glycolPoloxamerArticlelcsh:Pharmacy and materia medicaPharmacokineticsIn vivoUHPLC Ultra-high performance liquid chromatographyPharmacokineticsAUClast Area under the analyte concentration versus time curve from time zero to the time of the last measurable (non-below quantification level) concentrationEO Ethylene oxideNMP N-methyl-2-pyrrolidoneComputingMethodologies_COMPUTERGRAPHICSAUC∞ Area under the analyte concentration vs time curve from time zero to infinite timeP407 Poloxamer 407In vitro releasePoloxamerCMT Critical micellar temperatureGel erosionIn vitrot1/2 Apparent terminal elimination half-lifechemistryMDR-TB Multi-drug resistant tuberculosisAUC80h Area under the analyte concentration versus time curve from time zero to 80 htlast Sampling time until the last measurable (non-below quantification level) analyte plasma concentrationMRM Multiple reaction monitoringNuclear chemistrySustained releaseInternational Journal of Pharmaceutics: X
researchProduct

The continuous sample of working lives: Improving its representativeness

2017

This paper studies the representativeness of the Continuous Sample of Working Lives (CSWL), a set of anonymized microdata containing information on individuals from Spanish Social Security records. We examine several CSWL waves (2005–2013) and show that it is not representative for the population with a pension income. We then develop a methodology to draw a large dataset from the CSWL that is much more representative of the retired population in terms of pension type, gender and age. This procedure also makes it possible for users to choose between goodness of fit and subsample size. In order to illustrate the practical significance of our methodology, the paper also contains an applicatio…

J26Subsample selectionComputer scienceChi-square testContinuous Sample of Working LivesPopulationMicrodata (statistics)Sample (statistics)p valueRepresentativeness heuristicPensionsGoodness of fit0502 economics and businessEconometricsddc:330050207 economicsH55education050205 econometrics education.field_of_studyPensionPublic pension system05 social sciencesStratified samplingStratified samplingSocial securityC81General Economics Econometrics and Finance
researchProduct

Zvaigžņotā Debess: 2007/08, Ziema

2007

Latvijas Zinātnes padome, Latvijas Universitāte

Jezuītu darbība ĶīnāPārnova SN2006gyLīgatnes meteorīts – hipotēzeKrustvārdu mīklaArturs Balklavs-Grīnhofs - biogrāfijaLielā Suņa zvaigžņu blīvumsSāmu rūnu bungas – debess karteErnests GrasbergsLatviešu astronoms Staņislavs Vasiļevskis (1907-1988) – biogrāfijaLZA Astrofizikas laboratorija – 50Saturna pavadonis JapetsJauns Einšteina gredzensArnolds LibertsAstronomija un reliģijaGamma staru uzliesmojuma optiskā pēcblāzmaPiepūšamais planetārijs no NorvēģijasNEAR misijas noslēgumsLU Astronomiskais tornisZvaigžņotā debess 2007./08. gada ziemāGrimmu pasaka par zaķi un ezi – Mēness aptumsumsFizikas pasniedzējs Ilmārs EverssIvars ŠmeldsBārzdiņš JānisMarsa robots MSLAstronomiskās parādības - 2008Mars Sample Return misijaCitplanētu dažādībaEdgars MūkinsPlanētu redzamības kompleksā diagramma 2008CAP2007 konference Atēnās
researchProduct

Job insecurity and self-esteem: evidence from cross-lagged relations in a 1-year longitudinal sample

2003

The main purpose of the study was to investigate the cross-lagged relationships between job insecurity and self-esteem during a 1-year period, and thus assess the direction of the relationships between these two phenomena. The data were obtained by means of questionnaires which were completed twice, in 1999 and in 2000, by 457 Finnish employees. The results showed a cumulative relationship between job insecurity and self-esteem. In other words, high job insecurity seemed to predict subsequent low self-esteem, but at the same time, and to the same extent, low self-esteem seemed to predict subsequent high job insecurity. In addition, both perceived job insecurity and global self-esteem turned…

Job securityLongitudinal sampleJob insecuritymedia_common.quotation_subjectCross laggedSelf-esteemFollow up studiesPersonalityJob attitudePsychologySocial psychologyGeneral Psychologymedia_commonPersonality and Individual Differences
researchProduct

Intention to use mobile customer relationship management systems

2014

Purpose – The purpose of this paper is to investigate the behavioral intentions of business-to-business (B2B) sales managers to use mobile customer relationship management (CRM) systems in the course of their day-to-day activities. Design/methodology/approach – An extended Technology Acceptance Model (TAM) of mobile CRM system adoption is developed and tested with data from 105 international sales managers representing five B2B companies. Findings – The study extends the TAM framework with three additional constructs derived from mobile technology and sales force automation literature, namely personal innovativeness in the domain of IT, perceived risk, and perceived reachability. The model…

Knowledge managementtechnology acceptance modelperceived reachability in the domain of ITbusiness.industryCRM systemStrategy and ManagementSmall sampleIntention to useCustomer relationship managementpersonal innovativenessperceived riskIndustrial and Manufacturing EngineeringComputer Science ApplicationsManagement Information SystemsRisk perceptionSales force automationmobile technologyIndustrial relationsTechnology acceptance modelMobile technologyBusinessPractical implicationsB2B sales
researchProduct

The public–private sector wage gap in Latvia

2018

This study investigates the public-private sector wage gap in Latvia using microdata from the labour force survey. The severity of public sector wage cuts employed as a response to the economic crisis and subsequent recovery provides a test bed to analyse whether and how the public-private sector wage gap has adjusted after consolidation-driven wage cuts. Findings reveal that the observed wage gap is slightly in favour of the public sector; however, once differences in individual characteristics and selection effects are considered, results point to a private sector wage premium. Findings also suggest that the private sector wage premium has increased since the pre-crisis period. A signific…

Labour economicsLabour force surveypublic sector wagesmedia_common.quotation_subjectJ88WageOaxaca-Ransom decompositionMicrodata (statistics)lcsh:K4430-4675lcsh:HD72-88lcsh:Economic growth development planningpublic-private sector wage gap0502 economics and businessEconomicsddc:330050207 economicsJ31lcsh:Public finance050205 econometrics media_commonpublic–private sector wage gapbusiness.industryJ3305 social sciencesPublic sectorPrivate sectorDouble sample selectionPolitical Science and International RelationsbusinessGeneral Economics Econometrics and FinanceBaltic Journal of Economics
researchProduct

Unobserved Heterogeneity in Overeducation Models: Is Personality More Important than Ability?

2013

This paper compares the performance of selected personality aspects and ability on explaining the overeducation status of the individual. Ability is defined as the difference between the actual and the predicted income. Personality proves to be an important factor affecting the risk of overeducation. For females, personality allows to better explain mismatch than ability. For males, ability frequently, but not always, performs better than personality. Controlling for personality allows for better classification of the non-overeducated, while controlling for ability improves the classification of the overeducated. The study is done on the pooled sample of 23 European countries, as well as fo…

Labour economicsOvereducationPooled Samplemedia_common.quotation_subjectGeneral EngineeringEnergy Engineering and Power TechnologyLabour marketEducationEconometricsPersonalityPsychologyAbilitySelection (genetic algorithm)media_commonPersonalityProcedia Economics and Finance
researchProduct

Endotoxins in ophthalmic viscosurgical devices.

2003

Purpose To measure the endotoxin concentration (EC) of 25 commercially available, hyaluronic acid- and hydroxypropylmethylcellulose-based (HPMC) ophthalmic viscosurgical devices (OVDs). Methods The in vitro Limulus amebocyte lysate (LAL) assay, which indicates the presence of endotoxins originating from gram-negative bacteria, was used to determine the EC. The procedure was performed according to the European Pharmacopoeia/USP. EC including duplicate determinations, negative controls, dilution series with control standard endotoxin, dilution series with sample extract and positive sample control. Results 16 OVDs (Amvisc®, Amvisc® Plus, Biolon®, Coatel®, Healon®, Healon® GV, Healon®5, HPMC O…

LactoseLimulus testOphthalmologic Surgical ProceduresMethylcelluloseSensitivity and Specificity03 medical and health sciences0302 clinical medicineGram-Negative BacteriaOxazinesHumansConcentration factorHyaluronic AcidLimulus TestEndophthalmitisChromatographyPositive sampleChemistryReproducibility of ResultsGeneral MedicineDilutionEndotoxinsOphthalmologyLimulus amebocyte lysateImmunology030221 ophthalmology & optometry030217 neurology & neurosurgery
researchProduct

(Table 1) Trace element/Ca ratios of Orbulina universa shells from late Neogene Mediterranean samples

2008

A Mediterranean composite sedimentary record was analyzed for Ba/Ca ratios on carbonate shells of Orbulina universa planktonic foraminifer (Ba/Ca)carb providing the opportunity to study and assess the extent of freshwater inputs on the basin and possible impacts on its dynamics during the Tortonian to Recent period. A number of scanning electron microscope analyses and auxiliary trace element measurements (Mn, Sr, and Mg), obtained from the same samples, exclude important diagenetic effects on the studied biogenic carbonates and corroborate the reliability of (Ba/Ca)carb ratios in foraminifera calcite as indicators of seawater source components during the studied interval. A long-term trend…

Leg160Longitude of eventLithology composition faciesInductively coupled plasma - mass spectrometry (ICP-MS)Barium Calcium ratioOcean Drilling Program (ODP)Latitude of eventManganese/Calcium ratioOrbulina universa Barium/Calcium ratioAGEOrbulina universaLeg107Inductively coupled plasma mass spectrometry ICP MSOutcrop sampleManganese Calcium ratioSample code/labelEvent labelJoides ResolutionLithology/composition/faciesSample code labelStrontium/Calcium ratioDrilling/drill rigDrilling drill rigOrbulina universa δ13COrbulina universa Magnesium/Calcium ratioδ13CEarth System ResearchOcean Drilling Program ODPMagnesium Calcium ratioStrontium Calcium ratioComposite Core
researchProduct

Stable isotopic composition of three foraminifera species in ODP Hole 160-963D

2020

Carbon-rich layers exist at both sides of the Mediterranean Sea sedimentary record and are called sapropels and organic rich layers (ORLs), respectively in the eastern and western basins. They have different levels of organic carbon accumulation and seafloor oxygen deprivation. The most recent sapropel and ORL deposition have a different timing, 10.8-6.1 and 14.5-9.0 ka respectively. Here we investigate oxygen isotopic records of three foraminifera species that occupy different habitats within the Sicily Channel water column since ~ 12.0 ka, thus in the sill between the eastern and western Mediterranean basins. These data are ice volume-corrected, to get information on water masses density …

Leg160Uvigerina spp. δ13CORLNeogloboquadrina incompta δ13C9.2 ka event8 2 ka eventDEPTH sediment/rockNeogloboquadrina incomptaGlobigerinoides ruber δ13CAGE8.2 ka event9 2 ka eventDSDP/ODP/IODP sample designationδ18ODSDP ODP IODP sample designationSample code/labelGlobigerinoides ruber δ18OSapropel S1Globigerinoides ruberJoides ResolutionUvigerina spp. δ18OSample code labelDrilling/drill rigDrilling drill rigsediment rockLIWDEPTHUvigerina sppδ13CEarth System ResearchNeogloboquadrina incompta δ18O
researchProduct