Search results for " secondary"

Role of Cytoreductive surgery in recurrent ovarian cancer

2010

Ovarian cancer is the leading cause of death from gynecologic malignancy in western countries, primarily because over 60% of patients with ovarian cancer will experience disease recurrence. Primary cytoreductive surgery and combination chemotherapy are the cornerstones of the initial treatment for epithelial ovarian cancer. The management of recurrent ovarian cancer is less clear than that of primary disease. The management of recurrent ovarian cancer is largely based on systemic chemotherapy, with surgery being offered only in selected individuals. Despite this, the benefits of surgery has been shown in a meta-analysis by Bristow et al. where the survival is influenced by the completeness …

Laparoscopic surgical management of localized recurrent ovarian cancer: a single-institution experience

2014

Background: Optimally, secondary cytoreduction is acknowledged as a valid option in terms of oncologic outcome for patients with platinum-sensitive recurrent ovarian cancer. In cases of localized relapse, a laparoscopic approach has been attempted at various institutions, but studies on its role for this subset of patients still are limited. This report describes the authors' experience using laparoscopic secondary cytoreduction for patients with localized recurrent ovarian cancer. The results from a retrospective analysis of a prospective case series are reported. Methods: Between October 2011 and May 2013, 29 patients with localized recurrent ovarian cancer were selected for a laparoscopi…

Evaluación de competencias en salud: elaboración y validación de un cuestionario, primeros resultados

2019

espanolResumen: El objetivo de este trabajo ha consistido en elaborar y validar una herramienta en forma de cuestionario con la que averiguar las competencias en salud que posee el alumnado al finalizar la educacion obligatoria. Su importancia radica en que sirve para conocer el aprendizaje producido en Educacion para la Salud durante ese tiempo y, por tanto, es punto de referencia para la actuacion educativa posterior. El cuestionario trata 24 problemas significativos para la salud, ha sido sometido a juicio de expertos, evaluado con una prueba de legibilidad, con entrevistas a la poblacion diana, y con una prueba piloto con alumnos de 1o y 4o de la Educacion Secundaria Obligatoria (12 y 1…

Assessment of student engagement among junior high school students and associations with self-esteem, burnout, and academic achievement

2016

Journal for educational research online 8 (2016) 2, S. 136-157

CLIL modules and their affective impact on students with high English anxiety and low self-efficacy

2019

Many studies in recent years focused on the efficiency of bilingual education in different school settings. If a school pursues a regular implementation of CLIL modules instead of the establishment of proper CLIL streams, the student group that is affected by this teaching approach is much more diverse when compared to the preselected CLIL stream groups. In this regard, also students with high English anxiety and low self-efficacy will have to participate in the modules and it is particularly interesting to see how these student types deal with teaching units held in a foreign language. The study at hand presents results from an intervention at German schools with two biology units taught i…

Escherichia coli possesses two homologous anaerobic C4-dicarboxylate membrane transporters (DcuA and DcuB) distinct from the aerobic dicarboxylate tr…

1994

The nucleotide sequences of two Escherichia coli genes, dcuA and dcuB (formerly designated genA and genF), have been shown to encode highly homologous products, M(r) 45,751 and 47,935 (434 and 446 amino acid residues) with 36% sequence identity (63% similarity). These proteins have a high proportion (approximately 61%) of hydrophobic residues and are probably members of a new group of integral inner membrane proteins. The locations of the dcu genes, one upstream of the aspartase gene (dcuA-aspA) and the other downstream of the anaerobic fumarase gene (fumB-dcuB), suggested that they may function in the anaerobic transport of C4-dicarboxylic acids. Growth tests and transport studies with mut…

Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla

2001

Vibriosis due to Vibrio vulnificus serovar E (biotype 2) is one of the main causes of mortality in European eels cultured in Europe. The main objective of this study was to develop a vaccine and a vaccination procedure against this pathogen. With this aim, we tested several vaccine formulations (inactivated whole-cells with and without toxoids‹inactivated extracellular products‹from capsulated and uncapsulated strains, attenuated live vaccines and purified lipopolysaccharide [LPS]) on eels maintained under controlled laboratory conditions using different delivery routes (injection and immersion). To study the immune response we estimated antibody titers and bactericidal/bacteriostatic activ…

PROTEIN SECONDARY STRUCTURE PREDICTION: HOW TO IMPROVE ACCURACY BY INTEGRATION

2006

In this paper a technique to improve protein secondary structure prediction is proposed. The approach is based on the idea of combining the results of a set of prediction tools, choosing the most correct parts of each prediction. The correctness of the resulting prediction is measured referring to accuracy parameters used in several editions of CASP. Experimental evaluations validating the proposed approach are also reported.

Dal coltivo ai boschi vetusti in ambienti mediterranei: l’accumulo di carbonio e azoto in suolo e lettiera durante i primi 120 anni dall’abbandono.

2013

Fitting the Stocking Rate with Pastoral Resources to Manage and Preserve Mediterranean Forestlands: A Case Study

2015

Pasture practices have affected Mediterranean forest ecosystems for millennia, and they are still quite widespread in mountainous areas. Nevertheless, in the last decades, the stability of forest ecosystems has been jeopardized due to the abandonment of traditional agro-pastoral practices, so that the gradual reduction of open areas due to progressive succession processes has caused a high increase of grazing pressure by livestock and wild ungulates feeding on forest areas. This paper aims at showing a methodological approach for evaluating the effect of applying measures in order to improve the grazing value of grasslands and ecotonal patches and lower the grazing impact on native woodland…