Search results for " secretion"

showing 10 items of 490 documents

Coronary Stent Strut Fractures: Classification, Prevalence and Clinical Associations

2021

Introduction. The frequency, characteristics and clinical implications of Strut fractures (SFs) remain incompletely understood. Methods and results. A total of 185 (160 patients) newer-generation drug-eluting stents (DES) were imaged. SFs were found in 21 DES (11.4%) and were classified in four patterns: one single stacked strut (41%)

musculoskeletal diseasesmedicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyArticlecoronary stent03 medical and health sciencesfluids and secretions0302 clinical medicineRestenosisInternal medicineCoronary stentmedicineddc:610cardiovascular diseases030212 general & internal medicineStent thrombosisDevice failureStent restenosisstent thrombosisoptical coherence tomographybusiness.industryRLesion ComplexityGeneral Medicinebioresorbable scaffoldequipment and suppliesmedicine.diseaseThrombosissurgical procedures operativeCardiologyMedicinebusinessBioresorbable scaffoldstent restenosisJournal of Clinical Medicine
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Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

2017

The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…

parallel evolution0301 basic medicineBartonellaAMPylation; bacterial effector; filamentation induced by cAMP; parallel evolutionVirulence FactorsIn silico030106 microbiologyBiologyfilamentation induced by cAMPGenomeEvolution MolecularType IV Secretion Systems03 medical and health sciencesBacterial ProteinsBartonella InfectionsGeneticsAMPylationHumansEvolutionary dynamicsBacterial Secretion SystemsPhylogenyEcology Evolution Behavior and SystematicsPhylogenetic treeEffectorbiology.organism_classificationbacterial effectorVirology030104 developmental biologyEvolutionary biologyFilamentation induced by cAMP; AMPylation; Parallel evolution; Bacterial effectorHost-Pathogen InteractionsParallel evolutionAdaptationBartonellaResearch Article
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Effect of an insect growth regulator (halofenozide) on the cuticular hydrocarbons of Culex pipiens larvae

2013

The cuticular hydrocarbons of the fourth-instar larvae of Culex pipiens aged one and six days were analysed by gas chromatography and gas chromatography-mass spectrometry. The effect of an insect growth regulator (halofenozide = RH-0345) on the cuticular hydrocarbons was evaluated using newly moulted fourth-instar larvae of C. pipiens, at the lethal concentrations (LC50 = 12.58 and LC90 = 28.58 mu g/l). A previous study revealed that RH-0345 is toxic to larvae of C. pipiens by induction of precocious larval moulting. Several cuticular hydrocarbons (CHCs) were identified and many of the other compounds remained unknown. Our data show that the CHC classes consisted of n-alkanes (C23-C29) and …

profiles[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]animal structures[SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT]fungicuticularculicidaepopulationsaedes-aegypti dipterainsect growth regulatorslipidsculex pipienscuticlen-alkaneshydrocarbons[ SDV.OT ] Life Sciences [q-bio]/Other [q-bio.OT]cuticle secretioncomplex
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Human saliva, taste and food perception

2011

Human saliva, taste and food perception

salivagenetic structures[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritiondigestive oral and skin physiologybitternessperception gustativeinter-individual variability[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionfluids and secretionsstomatognathic systemvariabilité inter-individuelleAlimentation et NutritionFood and Nutritionamertumesalive;perception gustative;amertume;variabilité inter-individuelle;saliva;taste perception;bitterness;inter-individual variabilitysalive[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionpsychological phenomena and processestaste perception
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Mucin and α-amylase, the main salivary proteins, impact on aroma release

2014

International audience;  These data will be analyzed in regard to the following saliva parameters:  Amylase activity  Lipolytic activity  Anhydrase carbonic quantification  Lipocalines quantification  Total proteins quantity  Saliva viscosity  Saliva Flow Materials and Method  Tested molecules:  Static headspace analyses: 40min of equilibration at 30°C  Medium tested:

salivainteractionProtéine salivaire[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionstomatognathic diseasesfluids and secretionsaromastomatognathic system[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Aromes[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organsprotein[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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Consensus nomenclature for CD8(+) T cell phenotypes in cancer

2015

International audience; Whereas preclinical investigations and clinical studies have established that CD8+ T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8+ T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8+ T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8+ T cell immunity, leading to the emergence of dysfunctional CD8+ T cells. The existence of different types of CD8+ T…

senescenceT cellOncology and CarcinogenesisImmunology[SDV.CAN]Life Sciences [q-bio]/CancerBiologyCD8+ T cellsIFN gammaanergy03 medical and health sciencesstemness0302 clinical medicineImmune system[SDV.CAN] Life Sciences [q-bio]/Cancerexhaustionmedicine2.1 Biological and endogenous factorsImmunology and AllergyCytotoxic T cellAetiologyPoint of ViewCancer030304 developmental biologyCD8+ T cells; IFNγ; anergy; anticancer immunity; cytotoxicity; effector; exhaustion; senescence; stemness0303 health sciencesTumor microenvironmentCD8(+) T cellsCancermedicine.diseasePhenotype3. Good healthanticancer immunitymedicine.anatomical_structureeffectorOncologyImmunologycytotoxicityCytokine secretionCD8030215 immunologyIFNγ
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Determinación de Streptococcus mutans

2012

Se describen los pasos para determinar la presencia de Streptococcus mutans en saliva mediante un test inmunorreactivo

stomatognathic diseasesfluids and secretionsstomatognathic system32 Ciències Médiques
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Saliva in Food … How does it drive sensory perception?

2014

Saliva is a highly complex body fluid composed of many proteins, peptides, small organic molecules and ions. Saliva is produced and secreted by major and minor salivary glands to protect the mouth and to participate to the digestion. Generally distinction is made between resting saliva that is a result of autonomic stimulation, and stimulated saliva that is produced during chewing and taste stimulation. The link between saliva and sensory perception can be thus regarded through two main angles: the role of resting saliva as a background taste and the mechanistic role of saliva during eating. Indeed resting saliva (and its components) is continuously bathing our oral cavity and as such stimu…

taste[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionstomatognathic diseasessalivafluids and secretionsflavorstomatognathic system[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionfooddigestive oral and skin physiology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Flavour & saliva interaction – a brief overview

2015

Saliva is a highly complex body fluid composed of many proteins, peptides, small organic molecules and ions. Saliva is secreted at rest and during eating by major and minor salivary glands. Resting saliva is continuously bathing our oral cavity and as such stimulates our taste receptors playing thus a role in taste sensitivity against some active taste substances. Beside, during eating, foods are chewed and a significant level of stimulated saliva is rapidly incorporated in the bolus. This in-mouth phenomena impact on flavor release and thus perception through saliva-food physical interactions but also through the action of biological compounds (enzymes mainly) against the food matrix. Sali…

tastestomatognathic diseasessaliva[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionfluids and secretionsstomatognathic system[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionfoodfatdigestive oral and skin physiology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Distinctive attributes for predicted secondary structures at terminal sequences of non-classically secreted proteins from proteobacteria

2008

Abstract C- and N-terminal sequences (64 amino acid residues each) of 89 non-classically secreted type I, type III and type IV proteins (Swiss-Prot/TrEMBL) from proteobacteria were transformed into predicted secondary structures. Multivariate analysis of variance (MANOVA) confirmed the significance of location (C- or N-termini) and secretion type as essential factors in respect of quantitative representations of structured (a-helices, b-strands) and unstructured (coils) elements. The profiles of secondary structures were transcripted using unequal property values for helices, strands and coils and corresponding numerical vectors (independent variables) were subjected to multiple discriminan…

terminal sequencesMultiple discriminant analysisGeneral Immunology and MicrobiologybiologyQH301-705.5General Neurosciencesecondary structureComputational biologyLinear discriminant analysisbiology.organism_classificationBioinformaticsdiscriminant analysisGeneral Biochemistry Genetics and Molecular BiologyCross-validationSecretory proteinDiscriminantprotein secretionSecretionProteobacteriaBiology (General)General Agricultural and Biological SciencesProtein secondary structureproteobacteriaOpen Life Sciences
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