Search results for " sensitivity"
showing 10 items of 947 documents
Epidemic spread of ST1-MRSA-IVa in a neonatal intensive care unit, Italy
2012
Abstract Background Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged as an important pathogen in neonatal intensive care units (NICUs). The purposes of this study were to characterize methicillin-resistant isolates from an outbreak in a NICU, to examine the genetic traits and clonality of CA-MRSA, and to review the characteristics and outcomes of the neonatal cases and investigate the routes of entry and transmission of the MRSA outbreak strain in the NICU under study. Methods The study NICU practiced an active surveillance program for multidrug-resistant organisms, including weekly cultures for detection of MRSA from nasal swabs among all the …
Plasmid-mediated QnrS2 determinant from a clinical Aeromonas veronii isolate.
2008
The main objective of this study was to determine the prevalence of the Qnr determinants in clinical and environmental Aeromonas spp. A total of 52 Aeromonas sp. isolates identified by biochemical methods (5), 25 isolated from natural waters (1) and 27 isolated from clinical samples from hospitals in Valencia, Spain, were tested for quinolone resistance by the disk diffusion method (4) (nalidixic acid, 30 μg; oxolinic acid, 2 μg; flumequine, 30 μg; ciprofloxacin, 5 μg; and levofloxacin, 5 μg). Among the studied isolates, 27 showed resistance to nalidixic acid and susceptibility to ciprofloxacin, 24 isolates were susceptible to both nalidixic acid and ciprofloxacin, and only 1, the A. veroni…
Single Out-of-Resonance Dielectric Nanoparticles as Molecular Sensors.
2021
Light scattering from single nanoparticles and nanostructures is a commonly used readout method for nanosensors. Increasing the spectral sensitivity of resonant nanosensors to changes in their local surrounding has been the focus of many studies. Switching from spectral to intensity monitoring allows one to investigate nonresonant or out-of-resonance dielectric nanoparticles. Here, we systematically compared such dielectric silica nanoparticles with plasmonic gold nanorods by deriving analytical expressions and by performing experiments. The experiments show a similar sensitivity for the detection of an adsorbate layer for both particle types, which is in good agreement with theory. The fla…
Making a mountain out of a molehill: on the role of the rostral dorsal anterior cingulate and dorsomedial prefrontal cortex in conscious threat appra…
2013
According to appraisal theories fear and anxiety are elicited by the subjective evaluation of a situation or internal state as threatening. From this perspective anxiety disorders result from maladaptive, exaggerated threat appraisals that over-estimate the threatening consequences of often innocuous stimuli and situations. When these threat over-estimations occur at the level of conscious processing, they are referred to as catastrophizing and worrying. Both are major pathogenic processes in many clinical theories of anxiety. Until recently, little has been known about the neurobiological basis of normal and pathological conscious threat appraisal. Here, we review functional neuroimaging s…
La valutazione neuropsicologica tra significatività statistica e clinica
2008
Aspetti statistici e clinici pervadono tutte le fasi della valutazione neuropsicologica, dalla scelta dei test alla loro restituzione. Il presente articolo, utilizzando i dati di due ricerche come esempio, mette in evidenza l’importanza di ognuno dei due aspetti e di come questi influenzino le diverse fasi del processo di valutazione neuropsicologica e soprattutto la decisione finale e l’eventuale intervento.
GEANT4 simulation of the neutron background of the C6D6 set-up for capture studies at n_TOF
2014
The neutron sensitivity of the C6D6 detector setup used at n_TOF facility for capture measurements has been studied by means of detailed GEANT4 simulations. A realistic software replica of the entire n_TOF experimental hall, including the neutron beam line, sample, detector supports and the walls of the experimental area has beeni mplemented in the simulations. The simulations have been analyzed in the same manner as experimental data, in particular by applying the Pulse Height Weighting Technique. The simulations have been validated against a measurement of the neutron background performed with anatC sample, showing an excellent agreement above 1 keV. At lower energies, an additional compo…
Antibacterial and antioxidant activities in Sideritis italica (Miller) Greuter et Burdet essential oils
2006
Sideritis italica (Miller) Greuter et Burdet is a widespread Lamiacea in the Mediterranean region used in traditional medicine. Essential oils were antibacterial against nine ATCC and as many clinically isolated Gram-positive and Gram-negative bacterial strains. Antibacterial activity was also found against Helicobacter pylori: a dose-dependant inhibition was shown between 5 and 25 microg/ml. The antibacterial activity of the oils was expressed as MICs (minimum inhibitory concentrations) and MBCs (minimum bactericidal concentrations). At a concentration between 3.9 and 250 microg/ml the oils showed a significant antibacterial effect against both Gram-negative and Gram-positive bacteria. In …
Psychological models of development of idiopathic environmental intolerances: Evidence from longitudinal population-based data.
2021
Abstract The origin of idiopathic environmental intolerances (IEIs) is an open question. According to the psychological approaches, various top-down factors play a dominant role in the development of IEIs. The general psychopathology model assumes a propensity towards mental ill-health (negative affectivity) increases the probability of developing IEIs. The attribution model emphasizes the importance of mistaken attribution of experienced somatic symptoms; thus, more symptoms should lead to more IEIs. Finally, the nocebo model highlights the role of expectations in the development of IEIs. In this case, worries about the harmful effects of environmental factors are assumed to evoke IEIs. We…
Idiopathic Environmental Intolerance: A Comprehensive Model
2017
Idiopathic environmental intolerance refers to a group of poorly understood health conditions characterized by heterogeneous somatic symptoms that occur in response to environmental triggers, but for which no physiological causes can be found. We focus on three varieties, namely symptoms attributed to (a) chemical substances, (b) electromagnetic fields, and (c) infrasound and vibroacoustic sources. As no clear link with organ pathology or dysfunction has been established so far, we review critical evidence about alternative causal mechanisms as a platform for a novel unifying model of these conditions. There is consistent evidence that expectancy and nocebo mechanisms are critically involve…
Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity.
2012
Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity