Search results for " sign"
showing 10 items of 3133 documents
Early warning system in logistics project management
2017
Risk management is a vital process in all complex logistics project management. We discuss the concept of early warning system EWS dedicated to logistics project, which enable management under the conditions of uncertainty and risk. The complexity and uniqueness of the logistics projects as well as the discontinuity of the effects in the environment of goods and services, significantly impact the inability to eliminate the risks and subsequently lead to changes during execution. The introduction into companies and supply chains things such as: principles, methods, mechanisms of knowledge management and project risk, e.g. by implementing into the logistics project management the early warnin…
Stakeholder Analysis as a Source of Early Warning Signals in Logistics Projects
2017
Logistics projects are undertaken by a set of multiple organizations that engage resources from different logistics systems, production systems, management systems, social-cultural systems. They are subject to impact of wider economic and political environments. Logistics projects involve participants from diverse cultural environments, management practice. The article presents the essence and importance of stakeholders in projects including logistics projects. The author presents the basic issues related to stakeholders and early warning concept in project management. The specific research question is: How to implement the stakeholder relations management in early warning system dedicated …
EVALUATION OF EXTRAPYRAMIDAL INVOLVEMENT IN AMYOTROPHIC LATERAL SCLEROSIS (ALS): A PROSPECTIVE COHORT SURVEY
PROTEOMIC SIGNATURE OF BREAST CANCER TISSUES FOR PATIENTS STRATIFICATION
2012
Cukrzyca typu 2 i przewlekła choroba nerek jako czynniki rokownicze w ostrym zapaleniu trzustki
2019
Przeprowadzono analizę czynników rokowniczych ostrego zapalenia trzustki (OZT). Dokonano krytycznego przeglądu najważniejszych skali rokowniczych OZT: Apache II, Ransona, BISAP, Sofa, Marshalla. Wskazano na ich ograniczenia, ale i przydatność kliniczną we wczesnej stratyfikacji prognostycznej OZT. W diagnostyce różnicowej należy wyodrębniać etiologię alkoholową i żółciopochodną. Występująca przed zachorowaniem cukrzyca typu 2 i przewlekła choroba nerek znamiennie pogarszają przebieg OZT i powinny być włączone do skali rokowniczych. Wykazano, że obecność cukrzycy z poziomem HBA1C powyżej 6,5% wiąże się ze zwiększoną śmiertelnością wśród chorych na OZT i wydłuża się okres hospitalizacji o 5 d…
Inovatīva RF induktora barotāja datormodelēšana, izstrāde un eksperimenti
2018
Darbā tiek apskatītas dažādas iespējas ģenerēt augstas jaudas signālu ar atsevišķi regulējamu PWM (jaudas) koeficientu un frekvenci līdz 3 MHz. Tiek iztirzāti dažādi varianti praktiskā darba izpildei. Mūsdienās prasības germānija kristālu tīrībai aizvien aug un to audzēšana bezkontakta iekārtās var dot vajadzīgo rezultātu. LU ASI Atomfizikas un atmosfēras fizikas un fotoķīmijas laboratorijas efektīvās sadarbības projektā ar “Baltic Scientific Instruments Ltd” (lieto augstākās tīrības germānija kristālus) tika noskaidrots ka germānija kausēšanai vakuuma magnētiskajā levitācijā nepieciešams 30 kW un 0,5 - 3 MHz impulsa platumā regulējams (10 - 100% no jaudas) ģenerators, kas diemžēl komerciāl…
Activation of NF-kappaB and IL-8 by yersinia enterocolitica invasin protein is conferred by engagement of rac1 and MAP kinase cascades.
2003
International audience; Yersinia enterocolitica triggers activation of the nuclear factor (NF)-kappaB and production of the proinflammatory chemokine interleukin (IL)-8 in intestinal epithelial cells. This activation is due to adhesion of the bacteria via their outer membrane protein invasin to the host cells. Using Clostridium difficile toxins that specifically inactivate small GTPases, and transfection of inhibitory proteins of the Rho-GTPases, we demonstrate that Rac1, but not Cdc42 or Rho, is required for activation of NF-kappaB by invasin. Invasin activated the mitogen activated protein kinases (MAPK) p38 and c-Jun N-terminal protein kinase (JNK) but not extracellular signal regulated …
Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth
2010
Nerve Growth Factor (NGF)-induced neuronal differentiation requires the activation of members of the Rho family of small GTPases. However, the molecular mechanisms through which NGF regulates cytoskeletal changes and neurite outgrowth are not totally understood. In this work, we identify the Rac1-specific guanine exchange factor (GEF) Tiam1 as a novel mediator of NGF/TrkA-dependent neurite elongation. In particular, we report that knockdown of Tiam1 causes a significant reduction in Rac1 activity and neurite outgrowth induced by NGF. Physical interaction between Tiam1 and active Ras (Ras- GTP), but not tyrosine phosphorylation of Tiam1, plays a central role in Rac1 activation by NGF. In add…
Automated Railway Signs Detection. Preliminary Results
2019
Abstract Nowadays safety in railways is mostly achieved by automated system technologies such as ERTMS/ETCS. Nevertheless, on local railways (suburban and regional lines) several tasks still depend on the choices and actions of a human crew. With the aim to improve safety in such type of railways, this research proposes a system for the automatic detection and recognition of railway signs by means of the digital image processing technique. First field applications, carried out on the Italian railway network, show that the proposed system is very accurate (the percentage of correctly detected railway signs is about 97%), even at high train speeds.
Alfred Schütz: un’interpretazione sociologica di confine
1996
Il saggio riprende l'analisi schutziana concernente le strutture significative della vita quotidiana, per evidenziare come le "realtà multiple" potenziano, mediante il "principio di rilevanza", la percezione sinottica dei singoli soggetti e la conoscenza come esperienza trascendentale.