Search results for " single nucleotide polymorphisms"

showing 3 items of 13 documents

The genome-wide structure of two economically important indigenous Sicilian cattle breeds

2014

Genomic technologies, such as highthroughput genotyping based on SNP arrays, provided background information concerning genome structure in domestic animals. The aim of this work was to investigate the genetic structure, the genome-wide estimates of inbreeding, coancestry, effective population size (Ne), and the patterns of linkage disequilibrium (LD) in 2 economically important Sicilian local cattle breeds, Cinisara (CIN) and Modicana (MOD), using the Illumina Bovine SNP50K v2 BeadChip. To understand the genetic relationship and to place both Sicilian breeds in a global context, genotypes from 134 other domesticated bovid breeds were used. Principal component analysis showed that the Sicil…

Sicilian cattle breedsGenotypeGenetic StructuresAnimalMedicine (all)Sicilian cattle breedGenetic VariationGenetic StructureSingle nucleotide polymorphismsgenetic diversityBreedingPolymorphism Single NucleotideLinkage DisequilibriumSettore AGR/17 - Zootecnica Generale E Miglioramento Geneticosingle nucleotide polymorphismAnimalsCattlegenetic diversity genetic structure Sicilian cattle breeds single nucleotide polymorphismsSicilyGenome-Wide Association Study
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Genome-wide analysis of Italian sheep diversity reveals a strong geographic pattern and cryptic relationships between breeds

2014

Summary Italy counts several sheep breeds, arisen over centuries as a consequence of ancient and recent genetic and demographic events. To finely reconstruct genetic structure and relationships between Italian sheep, 496 subjects from 19 breeds were typed at 50K single nucleotide polymorphism loci. A subset of foreign breeds from the Sheep HapMap dataset was also included in the analyses. Genetic distances (as visualized either in a network or in a multidimensional scaling analysis of identical by state distances) closely reflected geographic proximity between breeds, with a clear north–south gradient, likely because of high levels of past gene flow and admixture all along the peninsula. Sa…

multidimensional scalingOvis ariesGenotypeanalysisIntrogressionContext (language use)BiologyBreedinggenetic diversity; genetic structure; genome-wide single nucleotide polymorphisms; multidimensional scaling; neighbor network; Ovis aries; oviniPolymorphism Single Nucleotidegenome-widegenome-wide single nucleotide polymorphisms; multidimensional scaling; neighbor networksingle nucleotide polymorphismsgenetic diversity; genetic structure; genome-wide; single nucleotide polymorphisms; multidimensional scaling; neighbor network; Ovis ariesGeneticsgenetic structureAnimalsneighbor networkInternational HapMap ProjectGeneticsGenetic diversityGenomeSheepSettore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICOgenome-wide single nucleotide polymorphismsGenetic VariationGeneral Medicinegenetic diversitybiology.organism_classificationBreedMouflonPhylogeographyItalyEvolutionary biologyoviniGenetic structureAnimal Science and ZoologyrevealsGenetic isolate
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Genomic Tools for the Characterization of Local Animal Genetic Resources: Application in Mascaruna Goat

2022

Italy contains a large number of local goat populations, some of which do not have a recognized genetic structure. The “Mascaruna” is a goat population reared for milk production in Sicily. In this study, a total of 72 individuals were genotyped with the Illumina Goat_IGGC_65K_v2 BeadChip with the aim to characterize the genetic diversity, population structure and relatedness with another 31 Italian goat populations. The results displayed a moderate level of genetic variability for Mascaruna, in concordance with the estimated values for Italian goats. Runs of homozygosity islands are linked to genes involved in milk production, immune response and local adaptation. Population structure anal…

single nucleotide polymorphismsSettore AGR/17 - Zootecnica Generale E Miglioramento Geneticolocal goat; single nucleotide polymorphisms; genetic structuregenetic structure local goat single nucleotide polymorphismsGeneral Veterinarygenetic structureAnimal Science and Zoologylocal goat
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