Search results for " sonic"
showing 9 items of 19 documents
The hedgehog receptor patched is involved in cholesterol transport.
2011
International audience; BACKGROUND: Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors, and one of the most affected Shh signaling steps found in these tumors is the regulation of the signaling receptor Smoothened by the Shh receptor Patched. In the present work, we investigated Patched activity and the mechanism by which Patched inhibits Smoothened. METHODOLOGY/PRINCIPAL FINDINGS: Using the well-known Shh-responding cell line of mouse fibroblasts NIH 3T3, we first observed that enhancement …
L'impronta sonica di manufatti di interesse artistico e oggetti museali
2008
Viene presentata una nuova tecnica di indagine non invasiva, sicura e rapida, per l’identificazione univoca e per il monitoraggio dell’integrità di manufatti costituiti da materiali rigidi, quali vasellame, statue e in generale oggetti lapidei, metallici o lignei. La tecnica sfrutta la capacità degli oggetti di vibrare se sollecitati da una sorgente esterna artificiale e si basa sullo studio delle oscillazioni smorzate indotte. Così è possibile costruire una impronta sonica degli oggetti stessi, una sorta di DNA che li possa identificare senza alcun dubbio ed eventualmente possa anche valutarne lo stato di consistenza meccanica (o integrità) come monitoraggio nel tempo. L’applicazione della…
L’indagine sonica ed ultrasonica come prassi necessaria alla conoscenza di strutture complesse. Il rimontaggio di una statua di epoca romana da Locri…
2008
Advances in microgeophysics for engineering and cultural heritage
2009
A large number of unconventional investigations have been implemented, tested, and validated in the field of microgeophysics, with the aim being to solve specific diagnostic and/or monitoring problems regarding civil engineering and cultural heritage studies. The investigations were carried out using different tomographic 2D and 3D approaches as well as different energy sources, namely sonic, ultrasonic and electromagnetic (radar) waves, electric potential fields, and infrared thermography. Many efforts have been made to modify instruments and procedures in order to improve the resolution of the surveys as well as to greatly reduce the time of the measurements without any loss of informatio…
Impact of the Extraction Method on the Chemical Composition and Antioxidant Potency of Rosmarinus officinalis L. Extracts
2023
Rosmarinus officinalis L. is a dietary source that produces polyphenols as secondary metabolites. These natural compounds with potent antioxidant abilities are increasingly recommended as a supplement to inhibit oxidative stress. In the current work, we evaluated the impact of the extraction method on the chemical composition of R. officinalis extract, especially on the content of carnosic (CA) and rosmarinic (RA) acids using UPLC-MS-DAD as well as on their antioxidant potency. Four extracts of Tunisian rosemary were obtained from non-conventional extraction techniques:ultrasound-assisted extraction (UAE),supercritical extraction (SFE) and UAE and SFE combined ((UAE-SFE(I), UAE-SFE(II)). Th…
Sonication-Induced Modification of Carbon Nanotubes: Effect on the Rheological and Thermo-Oxidative Behaviour of Polymer-Based Nanocomposites.
2018
The aim of this work is the investigation of the effect of ultrasound treatment on the structural characteristics of carbon nanotubes (CNTs) and the consequent influence that the shortening induced by sonication exerts on the morphology, rheological behaviour and thermo-oxidative resistance of ultra-high molecular weight polyethylene (UHMWPE)-based nanocomposites. First, CNTs have been subjected to sonication for different time intervals and the performed spectroscopic and morphological analyses reveal that a dramatic decrease of the CNT's original length occurs with increased sonication time. The reduction of the initial length of CNTs strongly affects the nanocomposite rheological behavio…
Advances in Nanoliposomes Production for Ferrous Sulfate Delivery
2020
In this study, a continuous bench scale apparatus based on microfluidic fluid dynamic principles was used in the production of ferrous sulfate-nanoliposomes for pharmaceutical/nutraceutical applications, optimizing their formulation with respect to the products already present on the market. After an evaluation of its fluid dynamic nature, the simil-microfluidic (SMF) apparatus was first used to study the effects of the adopted process parameters on vesicles dimensional features by using ultrasonic energy to enhance liposomes homogenization. Subsequently, iron-nanoliposomes were produced at different weight ratios of ferrous sulfate to the total formulation components (0.06, 0.035, 0.02, an…
Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…
2019
In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash
Growing the practice of vocal sketching
2015
Sketch-thinking in the design domain is a complex representational activity, emerging from the reflective conversation with the sketch. A recent line of research on computational support for sound design has been focusing on the exploitation of voice, and especially vocal imitations, as effective representation strategy for the early stage of the design process. A set of introductory exercises on vocal sketching, to probe the communication effectiveness of vocal imitations for design purposes, are presented and discussed, in the scope of the research-through-design workshop activities of the EU project SkAT-VG