Search results for " space"
showing 10 items of 4562 documents
Observatory science with eXTP
2019
Disponible preprint en: arXiv:1812.04023v1 [astro-ph.HE] [v1] Mon, 10 Dec 2018 19:00:52 UTC (4,376 KB)
SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B
2014
A proper balance between saturated and unsaturated fatty acids (FAs) is required for maintaining cell homeostasis. The increased demand of FAs to assemble the plasma membranes of continuously dividing cancer cells might unbalance this ratio and critically affect tumour outgrowth. We unveiled the role of the stearoyl-CoA desaturase SCD5 in converting saturated FAs into mono-unsaturated FAs during melanoma progression. SCD5 is down-regulated in advanced melanoma and its restored expression significantly reduced melanoma malignancy, both in vitro and in vivo, through a mechanism governing the secretion of extracellular matrix proteins, such as secreted protein acidic and rich in cysteine (SPAR…
A NEW DIALETICS CENTRE/PERIPHERY: CONSUMPTION PATTERNS AND PRACTICES IN THE SUBURBAN AREAS
2014
This paper deals with the analysis of current changes which have been recently shaping unprecedented urban structures in some suburban areas, due to the emerging of new consumptions spaces. In particular, the work aims at highlighting the effect of urban sprawl on the main Sicilian metropolitan areas, also moulded by the diffusion of the suburban retailing formats, in order to evaluate to what extent these dynamics have been contributing to the configuration of new urban landscapes and unprecedented socio-economic structures, not to mention the support in the process of containing social and economic marginalisation.
Data from: Assessing cetacean surveys throughout the Mediterranean Sea: a gap analysis in environmental space
2019
Heterogeneous data collection in the marine environment has led to large gaps in our knowledge of marine species distributions. To fill these gaps, models calibrated on existing data may be used to predict species distributions in unsampled areas, given that available data are sufficiently representative. Our objective was to evaluate the feasibility of mapping cetacean densities across the entire Mediterranean Sea using models calibrated on available survey data and various environmental covariates. We aggregated 302,481 km of line transect survey effort conducted in the Mediterranean Sea within the past 20 years by many organisations. Survey coverage was highly heterogeneous geographicall…
DNA nucleobase properties and photoreactivity: Modeling environmental effects
2009
Abstract The accurate ab initio quantum chemical (QM) method multiconfigurational second-order perturbation (CASSPT2)/complete active space self-consistent field (CASSCF) has been used in conjunction with molecular mechanics (MM) procedures to compute molecular properties and photoinduced reactivity of DNA/RNA nucleobases (NABs) in isolation and within a realistic environment, in which the double helix strand, the aqueous media, and the external counterions are included. It is illustrated that the use of an MM model is helpful both to account for short- and long-range effects of the system surrounding the QM molecular core and to provide the proper structural constraints that allow more acc…
Polymer colloids II, Robert M. Fitch, Plenum, New York, 1980, 684 pp. Price: $69.50
1981
Limiting concepts in extensional flow
1975
A characteristic feature of extensional flows is their potential capability of determining a stable, oriented structure in liquid materials containing elongated particles. With reference to flexible linear macromolecules, either in solution or as polymer melts, the limiting conditions under which such an oriented structure is actually possible are critically reviewed. It is seen that orientation can be obtained either when entanglements are present, i.e. when the polymer molecules form some sort of network, or, if the molecules behave entirely individually, only under very special circumstances. Further, if the objective is the “freezing” of the oriented structure in a partly crystalline, h…
Restricted and complete-active-space multiconfiguration linear response calculations of the polarizability of formamide and urea
1991
Abstract Using the polarized basis sets of Sadlej, we have carried out multiconfiguration linear response (MCLR) calculations of static and dynamic polarizabilities of water, carbon dioxide, formamide and urea. It is found that the polarized basis sets give a good description of the polarizabilities. The uncorrelates (self-consistent field) polarizabilities are in general 10% or more lower than the experimental values. The correlation as introduced in the complete-active-space (CAS) and restricted-active-space (RAS) MCLR calculations recovers the major part of this deviation.
Conformation of Polyethylene Glycol inside Confined Space: Simulation and Experimental Approaches
2021
The modification of the inner nanopore wall by polymers is currently used to change the specific properties of the nanosystem. Among them, the polyethylene glycol (PEG) is the most used to prevent the fouling and ensure the wettability. However, its properties depend mainly on the chain structure that is very difficult to estimate inside this confined space. Combining experimental and simulation approaches, we provide an insight to the consequence of the PEG presence inside the nanopore on the nanopore properties. We show, in particular, that the cation type in the electrolyte, together with the type of electrolyte (water or urea), is at the origin of the ion transport modification in the n…
Application of Nanoemulsions in the Synthesis of Nanoparticles
2018
Abstract Nanodroplets of a liquid in another immiscible liquid provide confined spaces in which chemical reactions can take place. If these reactions lead to the formation of nanoparticles, as it is the case for polymerization or precipitation reactions, nanodroplets can be used as templates for particle synthesis. The most common example of application of nanoemulsions for particle synthesis is the preparation of polymer nanoparticles by miniemulsion polymerization, but also inorganic materials can be produced in this way. Nanoemulsions are as well an excellent platform for preparing polymer/inorganic hybrid nanoparticles, either by using directly the templating effect of droplets during t…