Search results for " statistica"
showing 10 items of 2672 documents
Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases.
2018
Background: Epidemiologic evidence indicates common risk factors, including air pollution exposure, for respiratory and cardiovascular diseases, suggesting the involvement of common altered molecular pathways. Objectives: The goal was to find intermediate metabolites or metabolic pathways that could be associated with both air pollutants and health outcomes (“meeting-in-the-middle”), thus shedding light on mechanisms and reinforcing causality. Methods: We applied a statistical approach named ‘meet-in-the-middle’ to untargeted metabolomics in two independent case-control studies nested in cohorts on adult-onset asthma (AOA) and cardio-cerebrovascular diseases (CCVD). We compared the results …
Robustness of air quality indicators: a study of PM10 levels in Scotland
2008
Air quality assessment via functional principal component analysis
2009
The knowledge of the global urban air quality situation represents the first step to face air pollution issues. For the last decades many urban areas can rely on a monitoring network, recording hourly data for the main pollutants. Such data need to be aggregated according to different dimensions, such as time, space and type of pollutant, in order to provide a synthetic air quality index which takes into account interactions among pollutants and correlation among monitoring sites.This paper focuses on Functional Principal Component techniques for the statistical analysis of a set of environmental data x(spt), where s stands for the monitoring site, p for the pollutant and t for time, usuall…
Urban PM10 air quality indicator sensitivity
2008
Aggregate air pollution indices: a new proposal
2009
A new aggregate Air Quality Index (I2) to represent the global air pollution situation for a given city/region is proposed. Accounting for simultaneous exposure to common pollutants and their effects on human health, this index overcomes existing AQIs. Its goodness and utility is shown by a simulation plan and by an application to a real dataset on main pollutants.
The Dynamical Problem for a Non Self-adjoint Hamiltonian
2012
After a compact overview of the standard mathematical presentations of the formalism of quantum mechanics using the language of C*- algebras and/or the language of Hilbert spaces we turn attention to the possible use of the language of Krein spaces.I n the context of the so-called three-Hilbert-space scenario involving the so-called PT-symmetric or quasi- Hermitian quantum models a few recent results are reviewed from this point of view, with particular focus on the quantum dynamics in the Schrodinger and Heisenberg representations.
Biomarkers Related to Synaptic Dysfunction to Discriminate Alzheimer’s Disease from Other Neurological Disorders
2022
Recently, the synaptic proteins neurogranin (Ng) and α-synuclein (α-Syn) have attracted scientific interest as potential biomarkers for synaptic dysfunction in neurodegenerative diseases. In this study, we measured the CSF Ng and α-Syn concentrations in patients affected by AD (n = 69), non-AD neurodegenerative disorders (n-AD = 50) and non-degenerative disorders (n-ND, n = 98). The concentrations of CSF Ng and α-Syn were significantly higher in AD than in n-AD and n-ND. Moreover, the Aβ42/Ng and Aβ42/α-Syn ratios showed statistically significant differences between groups and discriminated AD patients from n-AD patients, better than Ng or α-Syn…
ISLANDS TOURISM SEASONALITY
2015
The islands of the European Union, generally associated with the sun and sea, attract the great majority of tourist flows in the summer months. This characteristic is shared by all the islands, be they in the Mediterranean or in the Baltic. However, through detailed analysis and the use of specific indicators, it was demonstrated that some islands are increasingly developing winter tourism in an effort to improve the annual occupancy rate of beds and mitigate seasonality curves. This study examines some islands that are located in different seas of the European Union, at different latitudes and hence in different climatic zones. These islands are: Cyprus (CY), Sicily (IT), Madeira (PT), and…
Finite-size scaling of charge carrier mobility in disordered organic semiconductors
2016
Simulations of charge transport in amorphous semiconductors are often performed in microscopically sized systems. As a result, charge carrier mobilities become system-size dependent. We propose a simple method for extrapolating a macroscopic, nondispersive mobility from the system-size dependence of a microscopic one. The method is validated against a temperature-based extrapolation [A. Lukyanov and D. Andrienko, Phys. Rev. B 82, 193202 (2010)]. In addition, we provide an analytic estimate of system sizes required to perform nondispersive charge transport simulations in systems with finite charge carrier density, derived from a truncated Gaussian distribution. This estimate is not limited t…