Search results for " status"

The Cost of Non-Alcoholic Steatohepatitis (NASH) in Europe and USA: The GAIN Study

2019

Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders. The progressive form of NAFLD, non-alcoholic steatohepatitis (NASH), leads to cirrhosis in a proportion of patients and so is associated with a substantial socio-economic burden which, coupled with a steadily rising prevalence, is becoming a growing public health challenge. The Global Assessment of the Impact of NASH (GAIN) study is a socioeconomic, prevalence-based burden of illness study across Europe (France, Germany, Italy, Spain and the United Kingdom) and the United States to determine the socio-economic burden of NASH in the real-world. Methods: GAIN was a retrospective, cross-sec…

Nutritional Support After Surgery of the Esophagus

2019

Surgery of the esophagus may be indicated for benign and malignant pathologies. Esophageal cancer represents the most frequent indication for surgical treatment, and the important nutritional concern arisen in relationship between cancer, surgery, and nutritional status of operated oncological patients has been explored by a vast scientific literature. Among benign pathologies indicating surgery involving the esophagus, achalasia has been largely studied, with surgery representing one of several effective therapeutic options.

2019

Abstract Objectives To use the estimates from the Global Burden of Disease Study 2016 to describe patterns of suicide mortality globally, regionally, and for 195 countries and territories by age, sex, and Socio-demographic index, and to describe temporal trends between 1990 and 2016. Design Systematic analysis. Main outcome measures Crude and age standardised rates from suicide mortality and years of life lost were compared across regions and countries, and by age, sex, and Socio-demographic index (a composite measure of fertility, income, and education). Results The total number of deaths from suicide increased by 6.7% (95% uncertainty interval 0.4% to 15.6%) globally over the 27 year stud…

Cuantificación y tratamiento de la congestión en insuficiencia cardíaca: una visión clínica y fisiopatológica

2022

Renal sodium and water retention with resulting extracellular volume expansion and redistribution are hallmark features of heart failure syndromes. However, congestion assessment, monitoring, and treatment represent a real challenge in daily clinical practice. This document reviewed historical and contemporary evidence of available methods for determining volume status and discuss pharmacological aspects and pathophysiological principles that underlie diuretic use.

Caries and quality of life in portuguese adolescents : impact of diet and behavioural risk factors

2018

Background The aim of this study was to assess the impact of diet and behavioural risk factors on caries appearance, and on oral health-related quality of life (OHRQoL) among Portuguese adolescents. Material and methods An epidemiological study conducted on 782 adolescents between 11-17 years, from randomly selected public schools of the 3rd cycle of basic education. All participants were asked for self-perceived general status health, about tooth-brushing habits and about the using of toothpaste with fluoride and a Food Frequency Questionnaire. The DMFT index (decayed, missing and filled teeth) was evaluated according to WHO criteria. To evaluate the OHRQoL, the 49-items Oral Health Impact…

The Addition of Transarterial Chemoembolization to Palliative Chemotherapy Extends Survival in Intrahepatic Cholangiocarcinoma

2021

Incidence and mortality of intrahepatic cholangiocarcinoma (iCCA) have been increasing continuously. Recent studies suggest that the combination of palliative chemotherapy (pCTX) and transarterial chemoembolization (TACE) improves overall survival (OS). This study aimed to evaluate the outcome of patients treated with TACE and pCTX in unresectable iCCA at our tertiary care center. A group of 14 patients was treated with both pCTX and TACE. The non-randomized control group of 59 patients received pCTX alone. Patients received a median of two pCTX lines in both groups. Those treated with TACE underwent a median number of 3.5 sessions. Median OS from the time of unresectability was 26.2 months…

Surgery vs. chemotherapy for ovarian cancer recurrence: what is the best treatment option

2020

Nowadays, the best treatment option for ovarian cancer recurrence is often subjective, can vary in the different centers and depend on personal experience. Arbeitsgemeinschaft Gynaekologische Onkologie (AGO)-DESKTOP studies have identified a population of patients who could benefit from secondary surgery. The results of the Gynecologic Oncology Group (GOG)-0213 study were recently published, which showed no advantage in terms of overall survival (OS) in patients with platinum-sensitive recurrent epithelial ovarian undergoing secondary cytoreductive surgery (SCS) compared to chemotherapy alone. Aim of this narrative review is to summarize the best aspects that can make ovarian cancer recurre…

Prevalence of traumatic injuries in deciduous dentition and associated risk factors in a Spanish children population

2021

Background: The frequency of traumatic dental injuries (TDI) in primary dentition and those agents that favor them present a great variability. Therefore, the objective of this study was to determine the prevalence of TDI in a population of Spanish preschoolers in temporary dentition and identify the factors associated with these injuries. Materials and Methods: an epidemiological observational prevalence study was carried out. A total of 343 children aged between 3 and 5 years were selected. A questionnaire was completed in relation to socioeconomic factors, cultural level, dietary habits and oral parafunction. Through an intraoral examination, information was collected on the occlusal cha…

Calidad de vida relacionada con la salud en personas con hipertensión y diabetes mellitus

2021

Objetivo: Determinar los factores sociodemográficos y clínicos asociados a la Calidad de Vida relacionada con la salud (CVRS) en personas con hipertensión arterial y diabetes mellitus tipo 2.Métodos: Estudio analítico de corte transversal en una muestra de 184 usuarios de un programa de control de riesgo cardiovascular en Bucaramanga (Colombia). Se utilizó el instrumento EQ-5D-3L para evaluar la calidad de vida. Un modelo de regresión lineal múltiple fue llevado a cabo usando como desenlace la Escala Visual Análoga y como posibles predictores las dimensiones del EQ-5D, ajustando por edad, sexo, grupo de intervención (variable instrumental) y variables clínicas como la patología de base y el…

Depressive symptoms in older female carers of adults with intellectual disabilities

2010

Background  This survey study aims to examine the prevalence and factors associated with depressive symptoms among primary older female family carers of adults with intellectual disabilities (ID). Method  In total, 350 female family carers aged 55 and older took part and completed the interview in their homes. The survey package contained standardised scales to assess carer self-reported depressive symptoms, social support, caregiving burden and disease and health, as well as adult and carer sociodemographic information. Multiple linear regressions were used to identify the factors associated with high depressive symptoms in carers. Results  Between 64% and 72% of these carers were classifi…