Search results for " subtype"

showing 10 items of 104 documents

Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

2020

Interferons are crucial for adaptive immunity and play an important role in the immune landscape of breast cancer. Using microarray-based gene expression analysis, we examined the subtype-specific prognostic significance of interferon-&gamma

OncologyMicroarrayReceptor ErbB-2animal diseasesKaplan-Meier Estimatelcsh:ChemistryMedicinelcsh:QH301-705.5Spectroscopymolecular subtypesHazard ratioGeneral MedicineinterferonMiddle AgedAcquired immune systemProgression-Free SurvivalComputer Science ApplicationsGene Expression Regulation NeoplasticReceptors EstrogenCohortFemaleReceptors ProgesteroneSignal Transductionmedicine.medical_specialtyBreast Neoplasmschemical and pharmacologic phenomenaDisease-Free SurvivalArticleCatalysisInorganic ChemistryInterferon-gammaBreast cancerImmune systembreast cancerInternal medicineBiomarkers TumorHumansPhysical and Theoretical ChemistryMolecular BiologyAgedNeoplasm Stagingbusiness.industryProportional hazards modelOrganic Chemistrybreast cancer ; prognosis ; interferon ; molecular subtypesbiochemical phenomena metabolism and nutritionGene signaturemedicine.diseaselcsh:Biology (General)lcsh:QD1-999bacteriaprognosisbusinessInternational Journal of Molecular Sciences
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Epidemiology of stroke and transient ischemic attacks: Current knowledge and perspectives

2015

International audience; Because of the growing size and aging of the world's population, the global burden of stroke is increasing dramatically. Current epidemiological data indicate that 16.9 million people suffer a stroke each year, which represents a global incidence of 258/100,000 year, with marked differences between high- and low-income countries, and an age-adjusted incidence 1.5 times higher in men than in women. Although primary prevention has contributed to a decrease in stroke incidence in high-income countries, the so-called 'epidemiological transition' has led to an increase in incidence in middle-to-low-income countries as well. In addition, the incidence of ischemic stroke in…

Pediatricsmedicine.medical_specialtyEpidemiologylate 20th-centuryPopulationPsychological intervention030204 cardiovascular system & hematologyGlobal Health03 medical and health sciences0302 clinical medicineetiologic subtypescaribbean population[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyEpidemiologymedicineGlobal healthPrevalenceHumansMortality30-day case-fatalityeducationTransient ischemic attackrisk-factorsStrokeDepression (differential diagnoses)education.field_of_studybusiness.industrycommunity strokeIncidence (epidemiology)Incidencecase-fatality ratesmedicine.disease3. Good healthStrokeEpidemiological transitionNeurologyRisk factorsIschemic Attack Transientquality-of-life1st-ever strokeNeurology (clinical)Francebusiness28-day case-fatality030217 neurology & neurosurgery[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDemography
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Normalizing the eating pattern with virtual reality for bulimia nervosa: a case report

2015

AbstractThe aim of the present study was to analyze the effects of a virtual reality (VR) component as a therapeutic tool to normalize eating patterns, as part of the cognitive-behavioral treatment of a bulimia nervosa (BN) patient. Results indicated that the patient made significant progress with her eating habits; binges and vomits were eliminated completely. Moreover, when the VR started the patient avoided food, especially meat (5 over 5), and it was reduction of this avoidance in the lasts sessions (2 and 3 over 5). It was also observed a reduction in the avoidance and the fear of eating (from 10 and 9 to 6 and 5 respectively) and increased the impulse control (from 2 to 7). The patien…

PsychotherapistBulimia nervosaCase studyMotivation to changeVirtual realityTrastornos de la conducta alimentariamedicine.diseaseVirtual realityEstudio de casoRealidad virtualPsychiatry and Mental healthClinical PsychologyGeneral psychopathologySample size determinationEating disordersmedicineDrive for thinnessEating habitsPsychologyBulimia purgative subtypeBulimia nerviosa subtipo purgativoClinical psychologyRevista Mexicana de Trastornos Alimentarios
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α1-Adrenoceptors in the rat cerebral cortex: New insights into the characterization of α1L- and α1D-adrenoceptors

2010

36 p., figuras y tablas, bibliografía

Rat cerebral cortexAdrenergic receptorG proteinInositol PhosphatesBiologyAlpha1-adrenoceptor subtypesBinding CompetitiveCytosolReceptors Adrenergic alpha-1medicineAnimalsRNA MessengerRats WistarBinding siteInositol phosphate[3H]prazosin binding studiesCellular localizationCerebral CortexPharmacologychemistry.chemical_classificationReverse Transcriptase Polymerase Chain ReactionCell MembraneRatsCell biologyCytosolmedicine.anatomical_structureGene Expression RegulationBiochemistrychemistryAlpha1L-adrenoceptorsCerebral cortexG-proteinsFemaleGuanosine TriphosphateIntracellularAlpha1D-intracellular localizationEuropean Journal of Pharmacology
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Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia

2020

Objectives Few studies have analyzed factors associated with delirium subtypes. In this study, we investigate factors associated with subtypes of delirium only in patients with dementia to provide insights on the possible prevention and treatments. Design This is a cross-sectional study nested in the "Delirium Day" study, a nationwide Italian point-prevalence study. Setting and participants Older patients admitted to 205 acute and 92 rehabilitation hospital wards. Measures Delirium was evaluated with the 4-AT and the motor subtypes with the Delirium Motor Subtype Scale. Dementia was defined by the presence of a documented diagnosis in the medical records and/or prescription of acetylcholine…

Rehabilitation hospitalmedicine.medical_specialtyUrinary systemSocio-culturaledementia; elderly; Motor subtypes of delirium; Aged; Cross-Sectional Studies; Humans; Inpatients; Italy; Delirium; Dementiaelderly03 medical and health sciences0302 clinical medicineInternal medicinemental disordersmedicineDementiaMotor subtypes of delirium dementia elderlyHumansdementia elderly Motor subtypes of delirium030212 general & internal medicineLS4_4Medical prescriptionGeneral NursingAgedPsychomotor learningInpatientsbusiness.industryHealth PolicyMedical recordMotor subtypes of deliriumMemantineDeliriumGeneral Medicinemedicine.diseasedementia; elderly; Motor subtypes of deliriumSettore MED/26 - NEUROLOGIACross-Sectional StudiesItalyDeliriumDementiaGeriatrics and Gerontologymedicine.symptombusiness030217 neurology & neurosurgerymedicine.drug
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Pathogenic microorganisms carried by migratorybirds passing through the territory of the island ofUstica, Sicily (Italy)

2011

Several studies have shown that migratory birds play an important role in the ecology, circulation and dissemination of pathogenic organisms. In October 2006, a health status evaluation was performed on a large population of migratory birds passing through the territory of Ustica (Italy), an island located on the migration route of many species of birds to Africa, and various laboratory tests were conducted. In total, 218 faecal swabs and the internal organs of 21 subjects found dead in nets were collected for bacteriological and virological examination, including avian influenza and Newcastle disease. In addition, 19 pooled fresh faecal samples were collected for mycological examination. T…

Salmonella bongoriVeterinary medicineCefotaximeNalidixic acidSentinel speciesNewcastle DiseaseDrug ResistanceNewcastle disease virusAnimals WildSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeNewcastle diseaseMicrobiologyBirdsFecesAntibiotic resistanceFood AnimalsYeastsGram-Negative BacteriamedicineDisease Transmission InfectiousAnimalsMigratory birds; Sicily; Viruses; Enterobacteriaceae; Fungi; Antibiotic-resistanceYersinia enterocoliticaSicilyPhylogenyDisease ReservoirsGeneral Immunology and MicrobiologybiologyBird Diseasesavian pathogens migratory birds resistance enterobacteriaceaebiology.organism_classificationInfluenza A virus subtype H5N1Anti-Bacterial AgentsSpecific Pathogen-Free OrganismsInfluenza A virusInfluenza in BirdsAnimal Science and ZoologyAnimal MigrationMitosporic Fungimedicine.drug
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Ischemic stroke subtypes and the implications for stroke management

2014

Settore MED/09 - Medicina InternaTOAST subtype Stroke management
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Krūts vēža molekulāro surogātapakštipu klīniski morfoloģiskais raksturojums sievietēm Latvijā un to saistība ar ķirurģiskās ārstēšanas veida izvēli u…

2015

Elektroniskā versija nesatur pielikumus

Surgical treatmentĶirurģiska ārstēšanaBreast cancerKrūts vēzisMedicīna un farmācijaMolekulārie surogātapakštipiVeselības aprūpeSurrogate molecular subtypesMedicīna
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Pandemic influenza A/H1N1 virus in a swine farm house in Sicily, Italy.

2012

This report describes a pandemic A/H1N1 (H1N1 pdm) virus outbreak occurred in December, 2009 in a swine farm used as research facility (Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione) for preclinical studies, located in Sicily, Italy. All the 13 pigs of the farm, showed cough, fever, inappetence and weakness. At the same time, an unvaccinated worker of the stabling showed influenza-like symptoms. RNAv extracted from two swabs collected from infected pigs resulted positive by Real Time RT-PCR for Influenza A virus. Furthermore, after growth on embryonated eggs, viral isolates were identified by Real Time RT-PCR specific for H1N1 pdm virus and characterized antigenically. …

Swine DiseasesReverse Transcriptase Polymerase Chain ReactionSwineA/H1N1 viruReal-Time Polymerase Chain ReactionDisease OutbreaksZoonosisInfluenza A Virus H1N1 SubtypeOrthomyxoviridae InfectionsInfluenza HumanAnimalsHumansSequencingFemalePandemicsSicilyPandemic influenza
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Stroke subtypes and their possible implication in stroke prevention drug strategies

2014

Thrombotic strokes can affect large or small arteries in the brain. Drugs to prevent atherosclerosis complication such as thrombotic strokes, should be drugs able to prevent the accumulation of intravascular fat, reduce vascular proliferation, decrease blood pressure levels with the resulting shear stress, reduce platelet aggregation, and possibly partially or totally reverse carotid plaques. Any of the commonly used antihypertensive drugs lower the incidence of stroke, with larger reductions in BP resulting in larger reductions in risk. Experimental and clinical data suggest that reducing the activity of the renin-angiotensin aldosterone system (RAAS) may have beneficial effects beyond the…

TOAST ClassificationDrugmedicine.medical_specialtySettore MED/09 - Medicina Internamedia_common.quotation_subjectBlood PressureStroke subtype preventionInternal medicinemedicineAnimalsHumanscardiovascular diseasesStrokeAntihypertensive AgentsRandomized Controlled Trials as Topicmedia_commonPharmacologyAspirinbusiness.industryDipyridamoleAtherosclerosismedicine.diseaseSurgeryStrokeDipyridamoleClinical trialBlood pressureCardiologyCardiology and Cardiovascular MedicineComplicationbusinessLipohyalinosisPlatelet Aggregation Inhibitorsmedicine.drug
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