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showing 10 items of 7948 documents

Prognostic Relevance of Cardiorespiratory Fitness as Assessed by Submaximal Exercise Testing for All-Cause Mortality: A UK Biobank Prospective Study

2020

Objective: To investigate if the inverse associations of cardiorespiratory fitness (CRF) with all-cause and cardiovascular mortality in the general population vary among individuals who are at different pre-test risk. Patients and Methods: CRF was assessed through submaximal bike tests in 58,892 participants aged 40-69 years who completed baseline questionnaires between January 1, 2006 and December 31, 2010 in the UK Biobank study. Participants were categorized into risk categories, which determined allocation to an individualized bike protocol. These were “minimal risk (1)”, “small risk (2)” and “medium risk (3)” groups (i.e., those who cycled at 50%, 35% of predicted maximal workload and …

AdultMaleUK Biobankmedicine.medical_specialtyDatabases FactualPopulationsubmaximal testRisk AssessmentMetabolic equivalentrisk predictionInterquartile rangeCause of DeathInternal medicinemedicineHumansProspective StudiesProspective cohort studyeducationAgedBiological Specimen Bankseducation.field_of_studycardiorespiratory fitnessFramingham Risk Scorebusiness.industryHazard ratioCardiorespiratory fitnessGeneral MedicineMiddle AgedPrognosisUnited KingdomCardiorespiratory FitnessCardiovascular DiseasesExercise Testall-cause mortalityFemaleRisk assessmentbusinessMayo Clinic Proceedings
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Incongruence Between Implicit Attachment Schemes and Unconscious Attachment Representations.

2019

Assessments based on reaction time and language-based interviews postulate that unconscious attachment processes be measured. Nevertheless, a possible empirical equivalence of these two approaches has not yet been investigated. To fill this void, the Adult Attachment Interview and the Implicit Association Test were implemented with a group of patients with panic disorder (n = 157, mean age = 29, SD = 2.47) based on the Structured Clinical Interview for DSM-IV, axis I and II disorders and a group of healthy individuals (n = 138). In total, the securely attached individuals showed significantly more positive attitudes toward their mother than the insecurely attached individuals. In the health…

AdultMaleUnconscious mindAdolescentMemory EpisodicNeuropsychological TestsDevelopmental psychologyAssociation03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansPatient groupAgoraphobiaAgedClinical interviewUnconscious PsychologyPanic disorderImplicit-association testMean ageMiddle Agedmedicine.diseaseObject AttachmentMother-Child Relations030227 psychiatryPsychiatry and Mental healthHealthy individualsPanic DisorderFemalePsychology030217 neurology & neurosurgeryAttachment measuresThe Journal of nervous and mental disease
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Efficacy of single-source rapid kV-switching dual-energy CT for characterization of non-uric acid renal stones: a prospective ex vivo study using ant…

2019

Purpose To investigate the accuracy of rapid kV-switching single-source dual-energy computed tomography (rsDECT) for prediction of classes of non-uric-acid stones. Materials and methods Non-uric-acid renal stones retrieved via percutaneous nephrolithotomy were prospectively collected between January 2017 and February 2018 in a single institution. Only stones >= 5 mm and with pure composition (i.e., >= 80% composed of one component) were included. Stone composition was determined using Fourier Transform Infrared Spectroscopy. The stones were scanned in 32-cm-wide anthropomorphic whole-body phantom using rsDECT. The effective atomic number (Zeff), the attenuation at 40 keV (HU40), 70 ke…

AdultMaleUrologymedicine.medical_treatmentStone compositionNephrolithotomy PercutaneousImaging phantom030218 nuclear medicine & medical imagingRapid kVp switchingRadiography Dual-Energy Scanned Projection03 medical and health scienceschemistry.chemical_compoundSingle-source0302 clinical medicineSpectroscopy Fourier Transform InfraredmedicineHumansUrolithiasiRadiology Nuclear Medicine and imagingProspective StudiesStone compositionKidney stonePercutaneous nephrolithotomyAgedRadiological and Ultrasound TechnologyPhantoms Imagingbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseDual-energy CTchemistry030220 oncology & carcinogenesisMann–Whitney U testRadiographic Image Interpretation Computer-AssistedUric acidFemaleUrinary CalculiKidney stonesDual energy ctTomography X-Ray ComputedNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaEffective atomic number
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A validation study of an Italian version of the "ID Migraine".

2007

Background.—Migraine is a highly prevalent and disabling disease which is substantially underdiagnosed in primary care. Recently, the ID Migraine, a self-administered questionnaire, consisting of only 3 items, was shown to be a valid and reliable screening instrument for migraine in primary care in the United States. Objective.—The aim of the present study was to validate an Italian version of the “ID Migraine” questionnaire. Methods.—Two hundred and twenty-two consecutive headache patients referring to 8 headache centers in Sicily (Italy) completed an Italian version of the ID Migraine. The responses to the questionnaire were compared with the diagnosis of headache made by a headache speci…

AdultMaleValidation studymedicine.medical_specialtyPediatricsAdolescentMigraine DisordersMEDLINEPrimary careNeurological disorderSensitivity and SpecificityPredictive Value of TestsSurveys and QuestionnairesPositive predicative valuemedicineHumansMass ScreeningId migrainebusiness.industryReproducibility of Resultsmedicine.diseasemigraine migraine burden migraine screening instruments ID MigraineItalyNeurologyMigrainePredictive value of testsPhysical therapyFemaleSettore MED/26 - NeurologiaNeurology (clinical)business
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[Esophageal digital videofluorography with water siphon test in the post-operative evaluation of the anti-reflux laparoscopic surgery].

2004

Background: In recent years digital videoefluorography (VFG) with water siphon test (WST) has been proposed just for diagnosing biatal bernia and/or gastroesophageal reflux. Patients and Methods: Fifteen patients undergone Laparoscopic Nissen (LN) for complicated GFRD associated to biatal bernia, were referred for VFG and WST in order to evaluate the functional results of surgery. At one- month videofluorographic control thirteen patients had just a minimal prolonged esophageal transit time hut only six of these had an early postoperative dysphagia, whereas at six montJh control the prolonged esophageal transit time was present in three patients two of which complained a very light dysphagi…

AdultMaleVideo RecordingFundoplicationWaterDysphagiaVideofuorographyRadiographic Image EnhancementHernia HiatalPostoperative ComplicationsSiphon testFluoroscopyGastroesophageal RefluxHumansNissen fundoplicationFemaleLaparoscopyDeglutition DisordersAnnali italiani di chirurgia
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Unconscious processing of Arabic numerals in unilateral neglect

2005

This study explores the processing of Arabic numerals in three patients with dense left unilateral neglect. Three tasks have been used: a test of visual awareness (is the stimulus on the left, on the right or on both sides?), a number comparison task (is the number larger or smaller than 5?), a number parity judgment task (is the number odd or even?). The test of visual awareness indicated that all three patients were completely unaware of the stimuli presented in the left hemifield. Despite this, the number comparison and number parity judgment tasks clearly indicated that Arabic numerals were unconsciously processed at semantic level (i.e. quantity). These results show that patients with …

AdultMaleVisual perceptionCognitive Neurosciencemedia_common.quotation_subjectExperimental and Cognitive PsychologyNeuropsychological Testsbehavioral disciplines and activitiesFunctional LateralityArabic numeralsNeglectPerceptual DisordersNumeral systemJudgmentBehavioral NeuroscienceReaction TimemedicineHumansmedia_commonNeglect Numerical processing Semantics Unconscious processingChi-Square DistributionUnconscious PsychologySettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaCognitionHemispatial neglectMiddle AgedMagnetic Resonance ImagingPattern Recognition VisualUnilateral neglectAcalculiaFemalemedicine.symptomPsychologyMathematicsPhotic StimulationCognitive psychologyNeuropsychologia
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Who is looking at me? The cone of gaze widens in social phobia

2011

Gaze direction is an important cue that regulates social interactions and facilitates joint attention. Although humans are very accurate in determining gaze directions in general, they have a surprisingly liberal criterion for the presence of mutual gaze. Using an established psychophysical task that required observers to adjust the eyes of a virtual head to the margins of the area of mutual gaze, we examined whether the resulting cone of gaze is altered in people with social phobia. It turned out that during presence of a second virtual person, the gaze cone's width was specifically enlarged in patients with social phobia as compared to healthy controls. The size of this effect was correla…

AdultMaleVisual perceptionJoint attentionEye Movementsgenetic structuresEye contactExperimental and Cognitive PsychologyNeuropsychological TestsEyePhobic disorderArts and Humanities (miscellaneous)Developmental and Educational PsychologyHumansAttentionSocial anxietyEye movementGazeCone (formal languages)Phobic DisordersVisual PerceptionFemaleCuesPsychologyHeadSocial psychologyCognition & Emotion
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Release of premotor activity after repetitive transcranial magnetic stimulation of prefrontal cortex

2008

In the present study we aimed to explore by means of repetitive transcranial magnetic stimulation (rTMS) the reciprocal influences between prefrontal cortex (PFC) and premotor cortex (PMC). Subjects were asked to observe on a computer monitor different pictures representing manipulations of different kind of tools. They had to produce a movement (go condition) or to keep the resting position (no-go condition) at the appearance of different cue signals represented by different colors shown alternatively on the hands manipulating the tools or on the picture background. Motor evoked potentials (MEPs) were collected at the offset of the visual stimuli before and after a 10 minute, 1 Hz rTMS tra…

AdultMaleVisual perceptionSocial Psychologymedia_common.quotation_subjectmedicine.medical_treatmentDecision MakingPrefrontal Cortextranscranial magnetic stimulation prefrontal cortex mirror neuronsDevelopmentMotor ActivityNeuropsychological Testsbehavioral disciplines and activitiesFunctional LateralityPremotor cortexBehavioral NeurosciencePerceptionmedicineHumansPrefrontal cortexMirror neuronmedia_commonAnalysis of VarianceBrain MappingElectromyographyMotor CortexBody movementEvoked Potentials MotorMagnetic Resonance ImagingTranscranial Magnetic StimulationElectric StimulationTranscranial magnetic stimulationmedicine.anatomical_structurenervous systemPattern Recognition VisualFemalePrimary motor cortexPsychologyNeuroscienceColor PerceptionPhotic Stimulation
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The Morquio A Clinical Assessment Program: Baseline results illustrating progressive, multisystemic clinical impairments in Morquio A subjects

2013

Abstract Objectives The objectives of this study are to quantify endurance and respiratory function and better characterize spectrum of symptoms and biochemical abnormalities in mucopolysaccharidosis IVA subjects. Methods MorCAP was a multicenter, multinational, cross sectional study amended to be longitudinal in 2011. Each study visit required collection of medical history, clinical assessments, and keratan sulfate (KS) levels. Results Data from the first visit of 325 subjects (53% female) were available. Mean age was 14.5 years. Mean ± SD height z-scores were − 5.6 ± 3.1 as determined by the CDC growth charts. Mean ± SD from the 6-minute-walk-test was 212.6 ± 152.2 m, revealing limitation…

AdultMaleVital capacitymedicine.medical_specialtyAdolescentCross-sectional studyEndocrinology Diabetes and MetabolismMucopolysaccharidosisMotor ActivityBiochemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyElosulfase alfaQuality of lifeSurveys and QuestionnairesInternal medicineActivities of Daily LivingGeneticsmedicineHumansMedical historyRespiratory functionChildExerciseMolecular BiologyGlycosaminoglycans030304 developmental biology0303 health sciencesbusiness.industryInfant NewbornInfantMucopolysaccharidosis IVmedicine.diseaseUnited StatesRespiratory Function TestsCross-Sectional StudieschemistryKeratan SulfateChild PreschoolPhysical EnduranceQuality of LifeMucopolysaccharidosis IVPhysical therapyFemalebusiness030217 neurology & neurosurgeryMolecular Genetics and Metabolism
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Longitudinal analysis of endurance and respiratory function from a natural history study of Morquio A syndrome

2015

Objectives: Baseline data from the Morquio A Clinical Assessment Program (MorCAP) revealed that individuals with Morquio A syndrome show substantial impairment in multiple domains including endurance and respiratory function (Harmatz et al., Mol Genet Metab, 2013). Here, 1- and 2-year longitudinal endurance and respiratory function data are presented.Methods: Endurance was assessed using the 6-minute walk test (6MWT) and the 3-minute stair climb test (3MSCT). Respiratory function was evaluated by measuring forced vital capacity (PVC) and maximum voluntary ventilation (MW). Data were analyzed using repeated measures ANCOVA models. Annualized estimates of change were determined using model es…

AdultMaleVital capacitymedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismMorquio A syndromeMotor ActivityMPS IVABiochemistry6 minute walk testEnduranceYoung AdultFEV1/FVC ratiochemistry.chemical_compoundEndocrinologyElosulfase alfaMorquio AForced Expiratory VolumeInternal medicineGeneticsHumansMedicineRespiratory functionMucopolysaccharidosis IVALongitudinal StudiesChildMolecular Biologybusiness.industryRespirationLongitudinal analysisInfantMucopolysaccharidosis IVRepeated measures designMaximal Voluntary VentilationMiddle AgedchemistryChild PreschoolAmbulatoryPhysical EnduranceCardiologyPhysical therapyFemalebusinessNatural history study
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