Search results for " test"
showing 10 items of 7948 documents
The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells
2010
Abstract Earlier studies have demonstrated that biosilica, synthesized by the enzyme silicatein, induces hydroxyapatite formation in osteoblast-like SaOS-2 cells. Here we study the effect of biosilica on the expressions of osteoprotegerin [OPG] and the receptor activator for NF-κB ligand [RANKL] in the SaOS-2 cell model. We show that during growth of SaOS-2 cells on biosiliceous matrices hydroxyapatite formation is induced, while syntheses of cartilaginous proteoglycans and sulfated glycosaminoglycans are down-regulated. Furthermore, quantitative real-time RT-PCR analysis revealed a strong time-depended increase in expression of OPG in biosilica exposed SaOS-2 cells while the steady-state e…
Inter- and intra-tester reliability of selected clinical tests in examining patients with early phase lumbar spine and sacroiliac joint pain and dysf…
2010
AbstractOf all patients with low back pain (LBP), 85% are diagnosed as “non-specific lumbar pain”. It has been postulated that the only reliable test is a straight leg raise test for detecting sciatic pain, and for other diagnostic subgroups, tests are of varying value. Only a few standardized tests exist to test function, inspection, mobility, pain, muscle flexibility or stability for patients with early phase lumbar spine and sacroiliac joint pain and dysfunction in the non-laboratory setting. The aim of this study was therefore to examine the inter- and intra-tester reliability of selected standardized clinical tests. Fifteen eligible, consecutive and voluntary LBP patients (aged 18–56 y…
Influence of sutures configuration on the strength of tendon-patch joints for rotator cuff tears treatment
2019
Abstract Purpose Massive rotator cuff tears are common in the aging population. The incidence of failed rotator cuff repairs is still quite high, especially in the treatment of full-thickness tears or revision repairs. In this context, natural and synthetic meshes can be used as augmentation scaffolds or as devices to close the gap between a retracted tendon and the bone. The purpose of this work is to evaluate the ultimate tensile strength of different tendon-patch joints in order to consider their use in the treatment of massive cuff tears. Materials and methods Porcine tendons and a synthetic low-density polypropylene mesh have been used. A preliminary study on the tensile strength of te…
Hearing loss in facioscapulohumeral dystrophy.
1986
Bilateral sloping high frequency hearing loss of 20–90 dB was found in six out of ten patients with infantile or adolescent onset FSHD. In all cases the basic defect could be traced to the cochlea. The outer hair cells of the basal turn are predominantly affected. In 20 patients with various other forms of muscular dystrophy or neuromuscular disorders with an FSH distribution, no sensorineural hearing loss was found. Myopathology of FSHD patients extended from mild to severe, often showing inflammatory infiltrates and type I fibre atrophy, without unequivocal differences between the two groups with and without hearing loss. It is concluded that cochlear dysfunction is a specific and frequen…
Il reciprocal teaching nella formazione iniziale degli insegnanti di sostegno della scuola secondaria di primo e secondo grado
2022
Attraverso il presente contributo si vuole verificare se nell’ambito del percorso di Specializzazione per le attività di sostegno per la Scuola secondaria di primo e secondo grado dell’Università degli Studi di Palermo, un approccio sistematico basato sul Reciprocal Teaching, con 1203 futuri insegnanti di sostegno di scuola secondaria di primo e secondo grado e materiali didattici appositamente predisposti, possa favorire il miglioramento della comprensione attraverso la capacità di sintesi e lo sviluppo di abilità metacognitive. Il Reciprocal Teaching, tra le varie strategie metacognitive è stata riconosciuta come la più solida dal punto di visto teorico e quella supportata da maggiori evi…
Eight new mutations and the expanding phenotype variability in muscular dystrophy caused by ANO5.
2012
Objective: Description of 8 new ANO5 mutations and significant expansion of the clinical phenotype spectrum associated with previously known and unknown mutations to improve diagnostic accuracy. Methods: DNA samples of 101 patients in 95 kindreds at our quaternary referral center in Finland, who had undetermined limb-girdle muscular dystrophy (LGMD), calf distal myopathy, or creatine kinase (CK) elevations of more than 2,000 IU/L, were selected for ANO5 genetic evaluation, and the clinical findings of patients with mutations were retrospectively analyzed. Results: A total of 25 patients with muscular dystrophy caused by 11 different recessive mutations in the ANO5 gene were identified. The …
Frequency and Correlates of Mild Cognitive Impairment in Myasthenia Gravis
2023
Background: Antibodies against acetylcholine receptors (AChRs) can also target nicotinic AChRs that are present throughout the central nervous system, thus leading to cognitive dysfunctions in patients with myasthenia gravis (MG). However, the presence of cognitive impairment in MG is controversial, and the factors that may influence this risk are almost completely unknown. In this study, the frequency of mild cognitive impairment (MCI) in MG, as well as the clinical, immunological, and behavioral correlates of MCI in MG were evaluated. Methods: A total of 52 patients with MG underwent a comprehensive assessment including motor and functional scales, serological testing, and neuropsychologi…
The Motivation Scale for the Game (EMJ) : study of the use of the game in educational contexts
2014
Aunque el juego ha sido estudiado y descrito desde múltiples ópticas, relevando su importancia en el desarrollo humano, su uso en el ámbito educativo pareciera estar restringido mayoritariamente al nivel de educación parvularia. En este sentido, la motivación de los docentes por la integración de nuevas metodologías (incluido el juego) parece ser una variable relevante a la hora de estudiar el cambio y la mejora en educación. El objetivo de este artículo es presentar una escala que puede ayudar al estudio de la motivación por el uso del juego y reportar sus características psicométricas. La Escala de Motivación por el Juego (EMJ) ha sido construida a partir del Modelo de Expectativa y Valor…
Revista electrónica de investigación y evaluación educativa
2014
Resumen tomado de la publicación Título, resumen y palabras clave en inglés y español La igualación equipercentil es un método estadístico en el cual los puntajes crudos de dos versiones de una prueba se consideran igualados si ellos corresponden al mismo rango percentilar en un grupo de examinados. En la igualación equipercentil se presenta una curva para describir las diferencias de dificultad de versión a versión. Se tiene como objetivo estimar la igualación equipercentil sin suavizado de las versiones 3 y 4, con la versión 2, por área temática del Examen de Habilidades y Conocimientos Básicos (EXHCOBA) que utiliza la Universidad Autónoma de Baja California (UABC) para la selección de as…