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showing 10 items of 7948 documents

Utility of CT in the diagnosis of pancreatic fistula after pancreaticoduodenectomy in patients with soft pancreas.

2009

OBJECTIVE: The purpose of this study was to evaluate the sensitivity and specificity of routine performance of CT on postoperative day 7 in patients at high risk of pancreatic fistula after pancreaticoduodenectomy. MATERIALS AND METHODS: Two radiologists analyzed images from CT examinations of 50 patients with soft pancreas 7 days after pancreaticoduodenectomy. Pancreatic fistula was defined at CT as a fluid collection close to the pancreaticogastric or pancreaticojejunal anastomosis. Clinicobiologic criteria for the diagnosis of pancreatic fistula were drain output of any measurable volume of fluid on or after postoperative day 3 that had an amylase content more than three times the serum …

AdultMalePancreas Computed Tomographymedicine.medical_specialtyAdolescentmedicine.medical_treatmentIohexolContrast MediaSerum amylaseSensitivity and SpecificityPancreaticoduodenectomyPancreatic FistulaPostoperative ComplicationsPredictive Value of TestsRisk FactorsHospital dischargeMedicineHumansRadiology Nuclear Medicine and imagingIn patientAgedAged 80 and overbusiness.industryPancreatic DiseasesGeneral MedicineMiddle AgedPancreaticoduodenectomymedicine.diseasePancreaticojejunal anastomosismedicine.anatomical_structurePancreatic fistulaPredictive value of testsFemaleRadiologybusinessPancreasTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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MR imaging of pancreatic changes in patients with transfusion-dependent beta-thalassemia major.

1999

The aim of this study was to evaluate MR imaging changes of the pancreas in patients with transfusion-dependent beta-thalassemia major.Twenty patients with transfusion-dependent beta-thalassemia major were examined using MR imaging at 0.5 T, with spin-echo T1-weighted, fast spin-echo T2-weighted, and gradient-echo T2*-weighted sequences. Image analysis was performed to assess pancreas-to-fat signal intensity ratios for all pulse sequences. Pancreatic exocrine and endocrine function and serum ferritin levels were assessed. Twenty healthy volunteers underwent MR imaging with the same three sequences and served as a control group.The pancreas-to-fat signal intensity ratio was significantly dec…

AdultMalePancreatic diseaseAdolescentFecesmedicineChymotrypsinHumansEndocrine systemBlood TransfusionTrypsinRadiology Nuclear Medicine and imagingPancreasPancreatic Elastasemedicine.diagnostic_testbiologybusiness.industryPulse (signal processing)beta-ThalassemiaCase-control studyMagnetic resonance imagingLipaseGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingFerritinPancreatic Function TestsHemoglobinopathymedicine.anatomical_structureAmylasesFerritinsbiology.proteinFemalebusinessNuclear medicinePancreas
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The neuropsychology of variant CJD: a comparative study with inherited and sporadic forms of prion disease.

2005

Objective: To assess cognitive function in variant Creutzfeldt-Jakob disease (vCJD). We describe the neuropsychological profiles of 10 cases and compare these data with cross sectional data obtained from patients with histologically confirmed sporadic CJD and cases with inherited prion disease with confirmed mutations in the prion protein gene. Methods: Patients referred to the Specialist Cognitive Disorders Clinic at the National Hospital for Neurology and Neurosurgery and the National Prion Clinic at St Mary's Hospital, London for further investigation of suspected CJD were recruited into the study. The neuropsychological test battery evaluated general intelligence, visual and verbal memo…

AdultMalePaperPediatricsmedicine.medical_specialtyPrionsanimal diseasesDNA Mutational AnalysisNeuropsychological TestsCreutzfeldt-Jakob SyndromePrion DiseasesNational Prion Clinicmental disordersmedicineDementiaHumansCognitive declinePsychiatrymedicine.diagnostic_testSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryNeuropsychologyNeuropsychological testCreutzfeldt-Jakob SyndromeMiddle Agedmedicine.diseasenervous system diseasesPsychiatry and Mental healthCross-Sectional StudiesAdult Cognition Disorders/etiology Creutzfeldt-Jakob Syndrome/complications Creutzfeldt-Jakob Syndrome/genetics Creutzfeldt-Jakob Syndrome/psychology Cross-Sectional Studies DNA Mutational Analysis Disease Progression Female Humans Male Middle Aged Neuropsychological Tests Prion Diseases/genetics Prion Diseases/psychology Prions/genetics Visual PerceptionDisease ProgressionVisual PerceptionSurgeryFemaleNeurology (clinical)Verbal memorybusinessCognition DisordersExecutive dysfunctionJournal of neurology, neurosurgery, and psychiatry
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Early language and behavioral regulation skills as predictors of social outcomes.

2012

Purpose In the present study, the authors examined the prospective associations among early language skills, behavioral regulation skills, and 2 aspects of school-age social functioning (adaptability and social skills). Method The study sample consisted of children with and without a familial risk for dyslexia. The authors analyzed the relations among children’s language (at age 2;6 [years;months] and age 5;0), behavioral regulation skills (at age 5;0), and social functioning (at age 8;0) using structural equation modeling. Subgroups of children with respect to language and behavioral regulation skills (at age 5;0) were identified through the use of mixture modeling. Results Among at-risk …

AdultMaleParentsLinguistics and LanguageMediation (statistics)Adolescentmedia_common.quotation_subjecteducationChild BehaviorLife skillsModels PsychologicalLanguage DevelopmentLanguage and LinguisticsStructural equation modelingDevelopmental psychologyDyslexiaSpeech and HearingYoung AdultSocial skillsPredictive Value of TestsRisk FactorsAdaptation PsychologicalmedicineHumansLanguage Development DisordersLongitudinal StudiesSocial Behaviormedia_commonFamily HealthDyslexiaSelf-controlMiddle AgedLanguage acquisitionmedicine.diseaseLanguage developmentChild PreschoolFemalePsychologyChild LanguageJournal of speech, language, and hearing research : JSLHR
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Test-retest reliability of a new questionnaire on the diet and eating behavior of one year old children

2015

Background As part of a sub-study in the ongoing Norwegian RCT ‘Fit for Delivery’, a new questionnaire, using a combination of food frequency, scale, and categorical questions to gather data on the diets and eating patterns of one year olds, was developed and tested for reliability by test-retest. Results Of 102 parents recruited to the study, 94 completed both test and retest. Correlation coefficients (Spearman’s r, and/or Cohen’s kappa, where applicable) were high for all categories of question, with a mean value of 0.72 for Spearman’s r for food frequency variables, and a mean value of 0.75 for Cohen’s kappa for non-numeric variables such as breast feeding status, showing very high test-…

AdultMaleParentsPediatricsmedicine.medical_specialtyHealth BehaviorPopulationBreastfeedingNorwegianGeneral Biochemistry Genetics and Molecular BiologyFood PreferencesSurveys and QuestionnairesHumansMedicineEating behaviorDiet questionnaireeducationCategorical variableReliability (statistics)Medicine(all)Analysis of Varianceeducation.field_of_studyReliability testingBiochemistry Genetics and Molecular Biology(all)business.industryInfantReproducibility of ResultsInfant/child nutritionFeeding BehaviorGeneral Medicinehumanitieslanguage.human_languageBottle FeedingDietTest (assessment)Breast FeedinglanguagePopulation studyFemalebusinessBreast feedingKappaResearch ArticleClinical psychologyBMC Research Notes
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Late-Emerging and Resolving Dyslexia

2015

This study focuses on the stability of dyslexia status from Grade 2 to Grade 8 in four groups: (a) no dyslexia in either grade (no-dyslexia, n = 127); (b) no dyslexia in Grade 2 but dyslexia in Grade 8 (late-emerging, n = 18); (c) dyslexia in Grade 2 but not in Grade 8 (resolving, n = 15); and (d) dyslexia in both grades (persistent-dyslexia, n = 22). We examined group differences from age 3.5 to age 14 in (a) reading, vocabulary, phonology, letter knowledge, rapid naming, IQ, verbal memory; (b) familial and environmental risk and supportive factors; and (c) parental skills in reading, phonology, rapid naming, verbal memory, and vocabulary. Our findings showed group differences both in read…

AdultMaleParentsRiskVocabularyAdolescentmedia_common.quotation_subjectbehavioral disciplines and activitiesDevelopmental psychologyDyslexiaChild DevelopmentLate-emerging dyslexiaReading (process)mental disordersDevelopmental and Educational PsychologymedicineHumansdysleksiaCognitive skillAge of OnsetChildmedia_commonLanguage TestsFamily risk for dyslexiaDyslexiaCognitionPhonologyPrognosis/dk/atira/pure/sustainabledevelopmentgoals/quality_educationmedicine.diseasenervous system diseasesPsychiatry and Mental healthEarly identificationChild PreschoolDisease ProgressionFemaleDisease SusceptibilityReading disabilitiesVerbal memoryAge of onsetPsychologySDG 4 - Quality EducationFollow-Up StudiesJournal of Abnormal Child Psychology
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Sensory processing in children with Autism Spectrum Disorder: Relationship with non-verbal IQ, autism severity and Attention Deficit/Hyperactivity Di…

2015

Abstract The main objective of this study was to analyze in a sample of children with ASD the relationship between sensory processing, social participation and praxis impairments and some of the child's characteristics, such as non-verbal IQ, severity of ASD symptoms and the number of ADHD symptoms (inattention and hyperactivity/impulsivity), both in the home and main-classroom environments. Participants were the parents and teachers of 41 children with ASD from 5 to 8 years old ( M  = 6.09). They completed the Sensory Processing Measure (SPM) to evaluate sensory processing, social participation and praxis; the Gilliam Autism Rating Scale (GARS-2) to evaluate autism severity; and a set of i…

AdultMaleParentsSensory processingAutism Spectrum Disordermedicine.medical_treatmentContext (language use)EnvironmentImpulsivitySeverity of Illness Indexbehavioral disciplines and activitiesDevelopmental psychologyPerceptual DisordersCognitionRaven's Progressive MatricesRating scaleSurveys and Questionnairesmental disordersDevelopmental and Educational PsychologymedicineHumansAttention deficit hyperactivity disorderChildIntelligence TestsfungiMiddle AgedSocial Participationmedicine.diseaseFacultyClinical PsychologyAttention Deficit Disorder with HyperactivityAutism spectrum disorderChild PreschoolAutismFemalePerceptionmedicine.symptomPsychologyResearch in Developmental Disabilities
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Recessive multiple epiphyseal dysplasia (rMED): phenotype delineation in eighteen homozygotes for DTDST mutation R279W.

2003

Multiple epiphyseal dysplasia (MED) is a generalised skeletal dysplasia that although relatively mild is associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. In the past, the disorder was subdivided into the milder Ribbing type, usually with flattened epiphyses,1 and the more severe Fairbank type with round epiphyses,2 but many cases were not classifiable as clearly either type.3 MED can be caused by mutations in at least six separate genes: COMP ,4–7 collagen IX ( COL9A1 , COL9A2 , and COL9A3 ),8–13 matrilin 3 ( MATN3 ),15 and the sulphate transporter, DTDST ( DTDST/SLC26A2 ). We have previously repor…

AdultMalePathologymedicine.medical_specialtyAdolescentAnion Transport ProteinsGenes RecessiveBiologySLC26A2ArginineOsteochondrodysplasiasShort statureMultiple epiphyseal dysplasiaGeneticsmedicineHumansChildGenetics (clinical)GeneticsAchondrogenesisSulfatesPoint mutationHomozygoteTryptophanChromosome MappingMembrane Transport ProteinsBiological TransportMiddle Agedmedicine.diseasePhenotypeGenetic defects of metabolism [UMCN 5.1]Amino Acid SubstitutionDysplasiaSulfate TransportersMutation (genetic algorithm)MutationMutation testingbiology.proteinFemalemedicine.symptomCarrier ProteinsLetter to JMGJournal of medical genetics
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Brain atrophy and lesion load in a large population of patients with multiple sclerosis

2005

Objective: To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. Methods: The study population consisted of 597 patients with MS and 104 control subjects. The MRI parameters were abnormal WM fraction (AWM-f), global WM-f (gWM-f), and GM fraction (GM-f). Results: Significant differences between patients with MS and control subjects included higher AWM-f and reduced gWM-f and GM-f. MRI data showed significant differences between patients with relapsing-remitting and secondary progressive forms of MS. Significant correlations bet…

AdultMalePathologymedicine.medical_specialtyAdolescentBrain mappingNerve Fibers MyelinatedCentral nervous system diseaseWhite matterMultiple sclerosisAtrophySex FactorsPredictive Value of TestsNeural PathwaysmedicineHumansAge of OnsetMultiple Sclerosis/physiopathologyAgedCross-Sectional StudieBrain MappingExpanded Disability Status Scalemedicine.diagnostic_testBrain/physiopathologybusiness.industryMultiple sclerosisBrainMagnetic resonance imagingInterferon-betaMiddle Agedmedicine.diseasePrognosislesion loadMagnetic Resonance ImagingMultiple Sclerosis/diagnosimedicine.anatomical_structureCross-Sectional Studiesmultiple sclerosiLinear ModelsDisease ProgressionEducational StatusFemaleNeurology (clinical)Age of onsetAtrophybusinessMultiple Sclerosis/complicationbrain atrophyMRI
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Vestibular Decruitment

1993

Torok studied the ratio obtained between the responses to two different heat stimulation intensities of the same temperature. A decrease in response to the strong stimulus (i.e., a diminished ratio) was called "vestibular decruitment," and was regarded as a topodiagnostic indicator of central vestibular lesion, reflecting "adaptation" or "fatigue." The authors studied the reliability of vestibular decruitment obtained by Torok's technique in the indication of central vestibular pathology. Twenty-eight normal individuals and 30 patients previously diagnosed by other methods with diffuse pathology of the central nervous system were evaluated. The results obtained show that the two stimuli use…

AdultMalePathologymedicine.medical_specialtyAdolescentCentral nervous systemStimulus (physiology)Central Nervous System DiseasesCaloric Testsotorhinolaryngologic diseasesmedicineHumansIn patientHabituationAgedVestibular systemmedicine.diagnostic_testbusiness.industryHyperacusisMiddle AgedVestibular Function TestsVestibular nerveHyperacusismedicine.anatomical_structureOtorhinolaryngologyFemalesense organsmedicine.symptomAudiometrybusinessThe Laryngoscope
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