Search results for " trauma"

Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury

2005

Inflammation plays a major pathological role in spinal cord injury (SCI). Although antiinflammatory treatment using the glucocorticoid methyprednisolone sodium succinate (MPSS) improved outcomes in several multicenter clinical trials, additional clinical experience suggests that MPSS is only modestly beneficial in SCI and poses a risk for serious complications. Recent work has shown that erythropoietin (EPO) moderates CNS tissue injury, in part by reducing inflammation, limiting neuronal apoptosis, and restoring vascular autoregulation. We determined whether EPO and MPSS act synergistically in SCI. Using a rat model of contusive SCI, we compared the effects of EPO [500-5,000 units/kg of bod…

Izjustās vainas saistība ar bērnībā piedzīvotu traumatisku pieredzi, delinkventas uzvedības biežumu un depresijai raksturīgajām pazīmēm jauniešiem

2022

Pētījuma mērķis bija noteikt sakarības starp izjusto vainu ar delinkventas uzvedības biežumu, bērnībā piedzīvotu traumatisku pieredzi un depresijas pazīmēm jauniešiem vecuma posmā no 14 līdz 18 gadiem. Pētījumā piedalījās 50 jaunieši vecumā no 14 līdz 18 gadiem, 32 meitenes, 17 zēni un 1 cits, kas elektroniski izpildījuši pētījuma ietvaros izveidoto anketu. Vidējais respondentu vecums bija 17 gadi. Jauniešu depresijas izteiktības pakāpe tika mērīta ar Bērnu depresijas aptauju (Children’s Depression Inventory; CDI; Kovacs, 1980; ko Latvijā adaptējusi S. Voitkāne un S. Miezīte, 1994). Jauniešu pieredze ar vardarbību ģimenē darba ietvaros tiek mērīta ar Bērnības traumas aptauja (CTQ), (Childho…

Work-related upper limb musculoskeletal disorders in paediatric laparoscopic surgery. A multicenter survey.

2013

Abstract Background Surgeons are at risk for developing work-related musculoskeletal symptoms (WMS). The present study aims to examine the physical factors and their association with WMS among pediatric laparoscopic surgeons. Methods A questionnaire consisting of 21 questions was created and mailed to 25 pediatric laparoscopic surgeons (LG). 23/25 surgeons (92%) completed the survey. The questionnaire was analyzed and then split into 2 groups. Group 1 (LG1) included surgeons with greater laparoscopic experience, and group 2 (LG2) included surgeons with less important laparoscopic experience. In addition, we constructed and sent to the same surgeons a similar questionnaire focused on WMS aft…

Laparoscopic treatment of mesenteric avulsion and intestinal perforation after blunt abdominal trauma: A report of a case

2020

Highlights • Intestinal injuries are quite involved in non-penetrating abdominal trauma after liver and spleen. • The incidence of small bowel injury after blunt abdominal trauma has increased nowadays, since high-energy transfer impacts producing large abdominal wall displacements are more frequent, such as car crash. • We report a case of a 49-year-old Caucasian woman, victim of a violent car crash, resulting in multiple small bowel perforations and mesenteric avulsion treated with laparoscopic approach. • Laparoscopy is a safe and feasible tool in selected patients with blunt abdominal trauma, both for diagnosis and treatment. • The prerequisites for applying mini invasive approach are b…

postmortem MDCT in the evaluation of air crash victims

2006

I traumi del fegato e delle vie biliari

2012

Sopravvivere all’omicidio di un familiare: i costi psichici della violenza mafiosa

2017

Le ricadute della presenza delle organizzazioni criminali di stampo mafioso sul territorio nazionale sono state esaminate da diverse discipline. Tuttavia, poca attenzione è stata ancora data ai danni psicologici che la mafia produce sui cittadini e su intere comunità. Alcune ricerche realizzate dal gruppo sulla psicologia del fenomeno mafioso dell’Università di Palermo hanno messo in luce come le continue pressioni psicologiche inferte dalla mafia alle vittime dirette ed indirette del crimine, producano significative e inevitabili ricadute sul loro sistema familiare e sociale con conseguenti intense ripercussioni sul benessere psico-fisico e sulla qualità della vita. In questo contributo ri…

Systemic hemostatic agents initiated in trauma patients in the pre-hospital setting: a systematic review

2022

Abstract Purpose The effect of systemic hemostatic agents initiated during pre-hospital care of severely injured patients with ongoing bleeding or traumatic brain injury (TBI) remains controversial. A systematic review and meta-analysis was therefore conducted to assess the effectiveness and safety of systemic hemostatic agents as an adjunctive therapy in people with major trauma and hemorrhage or TBI in the context of developing the Italian National Institute of Health guidelines on major trauma integrated management. Methods PubMed, Embase, and Cochrane Library databases were searched up to October 2021 for studies that investigated pre-hospital initiated treatment with systemic hemostati…

Clinical practice guideline for the integrated management of major trauma by the Italian National Institute of Health: process and methods

2021

Background. Major trauma describes serious injuries requiring lifesaving interventions or resulting in long-term disability; it represents about 8% of all deaths worldwide. Specific guidelines can help reduce deaths and disabilities, provided they adhere to high quality and trustworthiness standards. This article aims at introducing the development process of the Istituto Superiore di Sanità, ISS (Italian National Institute of Health) guideline for major trauma integrated management. Methods. We applied the ISS methodological standards including the GRADE-ADOLOPMENT approach for adoption, adaptation, and de novo development of trustworthy guidelines. Results. The scope was formulated by the…

The face of conflict: Significant sharp force trauma to the mid-facial skeleton in an individual of probable 16th–17th century date excavated from By…

2016

A variety of injuries have always been associated with violence, consequences of which people had to deal with. In this paper we present a complex of craniofacial and dental injuries resulted from sharp force trauma. The basis of our study was historical skeletal material excavated from archeological site in Byczyna (11th–17th century), Poland. An individual whose skeleton was exhumed from the grave No. 610 exhibited healed, oblique trauma of the left maxilla, damage to the crowns of right central and lateral incisors and concomitant luxation of the right maxillary central incisor. We describe the mechanism of this trauma and complications that resulted from damage to the masticatory appara…