Search results for " trip"
showing 10 items of 535 documents
CCDC 1969476: Experimental Crystal Structure Determination
2021
Related Article: Maria-Gabriela Alexandru, Diana Visinescu, Beatrice Cula, Sergiu Shova, Renato Rabelo, Nicolás Moliner, Francesc Lloret, Joan Cano, Miguel Julve|2021|Dalton Trans.|50|14640|doi:10.1039/D1DT02512K
Interaction of UO2(2+) with ATP in aqueous ionic media.
2005
Interaction of dioxouranium(VI) (uranyl) ion with ATP was studied by ligand/proton and metal/hydroxide displacement technique, at very low ionic strength and at I=0.15 mol L(-1), in aqueous Me4NCl and NaCl solutions, at t=25 degrees C. Measurements were carried out in the pH range 3-8.5, before the formation of precipitate. Computer analysis allowed us to find the quite stable species UO2(ATP)H2(0), UO2(ATP)H-, UO2(ATP)2-, UO2(ATP)2(6-), UO2(ATP)2H2(4-) and UO2(ATP)(OH)3- whose formation constants are (at I=0 mol L(-1)) logbeta(112)=18.21, logbeta(111)=14.70, logbeta(110)=9.14, logbeta(120)=12.84, logbeta(122)=24.82, and logbeta(11-1)=2.09, respectively. Different values were obtained in th…
Recovery of human fibroblasts from attack by the pore-forming alpha-toxin of Staphylococcus aureus.
1994
When applied at low concentrations (10 micrograms/ml), staphylococcal alpha-toxin generates a small channel in keratinocyte and lymphocyte membranes that permits selective transmembrane flux of monovalent ions. Here we show that a moderate concentration (1-50 micrograms/ml) of alpha-toxin similarly produces a small pore in membranes of human fibroblasts. This process leads to rapid leakage of K+ and to a drop in cellular ATP to 10-20% of normal levels in 2 h. In the presence of medium supplemented with serum and at pH 7.4, the cells are able to recover from toxin attack, so that normal levels of K+ and ATP are reached after 6-8 h at 37 degrees C. The repair process is dependent on the prese…
Subcytocidal attack by staphylococcal alpha-toxin activates NF-kappaB and induces interleukin-8 production.
2001
ABSTRACTFormation of transmembrane pores by staphylococcal alpha-toxin can provoke a spectrum of events depending on target cell species and toxin dose, and in certain cases, repair of the lesions has been observed. Here, we report that transcriptional processes are activated as a response of cells to low toxin doses. Exposure of monocytic (THP-1) or epithelial (ECV304) cells to 40 to 160 ng/ml alpha-toxin provoked a drop in cellular ATP level that was followed by secretion of substantial amounts of interleukin-8 (IL-8). Cells transfected with constructs comprising the proximal IL-8 promoter fused to luciferase or to green fluorescent protein cDNA exhibited enhanced reporter gene expression…
Influence of inorganic pyrophosphate on the kinetics of muscle pyruvate kinase: a simple nonallosteric feedback model.
2002
Potassium pyrophosphate was used instead of ATP as a model ligand for magnesium cation for the study of effector influence on the kinetics of pyruvate kinase muscle isozyme M1. The pyruvate kinase activation by low concentration of pyrophosphate and inhibition by high concentration of pyrophosphate was considered to be the result of reversible reactions of magnesium cation with pyrophosphate, ADP, ATP, and PEP. The apparent Km and Vm or in some cases the pseudo-first order reaction rate constant (instead of Km and Vm) of pyruvate kinase at any given pyrophosphate concentration were analysed as a function of concentration of free magnesium cation and its complexes with all ligands present in…
A hypothetical model of the influence of inorganic phosphate on the kinetics of pyruvate kinase
2000
This paper presents a simple solution to the problem of approximating the calculated curve of reaction progress to the measured curve which is usually disturbed by initial oscillation of auxiliary lactate dehydrogenase (LDH) reaction. The experiments leading to the determination of the apparent Km for phosphoenolpyruvate (PEP) and Vm were performed. For precise estimation of kinetic parameters (Km and Vm) of the M1 isozyme of pyruvate kinase (PK), measured by coupling it to LDH reaction, the sequence of Michaelis‐Menten for pyruvate kinase and second-order kinetics for lactate dehydrogenase reaction as well as a non-zero initial concentration of lactate was assumed. The functions of apparen…
Additive Steiner triple systems
2014
A Steiner triple system is additive if it can be embedded in a commutative group in such a way that the sum of the three points in any given block is zero. In this paper we show that a Steiner triple system is additive if and only if it is the point-line design of either a projective space PG(d,2) over GF(2) or an affine space AG(d,3) over GF(3), for d ≥ 1. Our proof is based on algebraic arguments and on the combinatorial characterization of finite projective geometries in terms of Veblen points.
An algebraic representation of Steiner triple systems of order 13
2021
Abstract In this paper we construct an incidence structure isomorphic to a Steiner triple system of order 13 by defining a set B of twentysix vectors in the 13-dimensional vector space V = GF ( 5 ) 13 , with the property that there exist precisely thirteen 6-subsets of B whose elements sum up to zero in V , which can also be characterized as the intersections of B with thirteen linear hyperplanes of V .
Steiner Loops of Affine Type
2020
Steiner loops of affine type are associated to arbitrary Steiner triple systems. They behave to elementary abelian 3-groups as arbitrary Steiner Triple Systems behave to affine geometries over GF(3). We investigate algebraic and geometric properties of these loops often in connection to configurations. Steiner loops of affine type, as extensions of normal subloops by factor loops, are studied. We prove that the multiplication group of every Steiner loop of affine type with n elements is contained in the alternating group An and we give conditions for those loops having An as their multiplication groups (and hence for the loops being simple).
Das kompositorische Verfahren in Jean Moutons Quadrupelkanon Nesciens mater virgo virum
2012
Anhand der kompositorischen Probleme, die sich bei der Konzeption mehr als zweistimmiger Kanons ergeben, wird der Frage nachgegangen, wie der konkrete Kompositionsprozess um 1500 ausgesehen haben konnte. Eine Analyse von Jean Moutons Motette Nesciens mater zeigt, dass die Wechselwirkungen zwischen Kanonkonzeption, Klangfolge und melodischer Gestaltung eine simultane Kompositionsweise voraussetzen, in der die Klangfolge wechselnde Verhaltnisbestimmungen als Resultat und Voraussetzung der kontrapunktischen Konfiguration erfahrt: Der Wechsel von der Sukzessiv- zur Simultankonzeption erscheint in Bezug auf komplexe Kanonbildungen als ein verfahrenstechnisches Erfordernis.