Search results for " use"
showing 10 items of 7471 documents
Mediating Effects of Global Negative Effect Expectancies on the Association between Problematic Cannabis Use and Social Anxiety
2017
The relationship between social anxiety and cannabis use among adolescents and young adults is a highly debated topic. In this cross-sectional study, we tested whether cannabis use expectancies mediated the association between social anxiety and cannabis use severity in a sample of 343 young adults (74.3% male) who used cannabis. They completed self-report measures for the screening of problematic cannabis use (Cannabis Use Problems Identification Test) and social anxiety symptoms (Social Interaction Anxiety Scale and Social Phobia Scale). A multiple mediation analysis was used to test whether marijuana effect expectancies mediate social anxiety effect on problematic cannabis use. Social an…
Reflecting on Work Values with Young Unemployed Adults in Finland
2019
In this article, we explore the internal conversations about the work values of young unemployed adults in Finland. We draw on the theoretical concept of internal conversation by Margaret Archer in order to shift the focus from the individual work values to the interplay between subjective concerns and structural circumstances. The data consist of six group interviews conducted among 29 young unemployed adults. We argue that the internal conversations on work values of young unemployed adults constitute five significant concerns: self-realization and opportunity to contribute to society; sufficient income to live independently; social expectations; challenges of finding employment; and unsu…
Key Issues in Enterprise Architecture Adoption in the Public Sector
2018
This paper examines the challenges of enterprise architecture (EA) adoption in public sector organisations. So far, demonstrating the benefits of EA has appeared difficult in this context, and the results in transforming public sector remain modest: Both the penetration and the maturity of EA appear rather low. In the academia, however, the adoption of EA has gained less interest than the EA development and methodologies. Hence, there is a need for research on what are the challenges of EA adoption, and how to overcome them. This paper presents the results of an expert survey on the challenges of EA adoption in the Finnish public sector. The analysis of quantitative data, supported with a q…
Triggering sustainability communication in a B2B context: combining action research and sensemaking
2021
PurposeThe paper explores processes associated with the adoption of corporate sustainability communication in a B2B context. It employs a combined action research and sensemaking approach to document moments that precede the initiation of external sustainability communication.Design/methodology/approachThe paper is the outcome of an action research project, where we examine the case of one industrial company that was silent on its multiple sustainability-related practices, but recently decided to become more transparent to the outside world. A processual approach to sensemaking is adopted to show how organisational and non-organisational members actively participated in meaning co-construct…
Los nuevos derechos sociales: El derecho al cuidado como fundamento del pacto constitucional
2016
ResumenNos encontramos ante un momento histórico y político que sugiere una revisión constitucional, con necesidades específicas y diferentes a las de 1978. Existen nuevas demandas que exigen que se revise el pacto constitucional. Algunas afectan directamente al catálogo de derechos, especialmente a los llamados derechos sociales, y se refieren por un lado, a la necesidad de otorgar a los derechos sociales ya reconocidos la consideración de fundamentales con todo lo que ello conlleva; y por otro, a la necesidad de crear nuevos derechos. El previsible aumento de personas necesitadas de cuidados, la escasez de servicios públicos para su asistencia, el tipo de cuidado informal prestado casi ex…
Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled…
2013
Obesity is an unfavorable prognostic factor in breast cancer (BC) patients regardless of menopausal status and treatment received. However, the association between obesity and survival outcome by pathological subtype requires further clarification. METHODS: We performed a retrospective analysis including 5,683 operable BC patients enrolled in four randomized clinical trials (GEICAM/9906, GEICAM/9805, GEICAM/2003-02, and BCIRG 001) evaluating anthracyclines and taxanes as adjuvant treatments. Our primary aim was to assess the prognostic effect of body mass index (BMI) on disease recurrence, breast cancer mortality (BCM), and overall mortality (OM). A secondary aim was to detect differences o…
Vers un environnement informatisé d'évaluation de la qualité ergonomique d'interfaces multimédia : Étude exploratoire
2000
Our objective is to encourage the human-computer interface designers to be more interested in the uses made of their product by taking into account to a higher degree the human-factor in the testing phase which often is too focused on technical aspects. We want to facilitate the integration of the user as a source of evaluation during the testing phase. Our aim is to offer the designer a software environment of practical tests that allow them to have their own products evaluated by their users. We undertook an experiment to explore the feasibility of this project.
Vers un environnement informatisé d'évaluation de la qualité ergonomique d'interfaces multimédia : Étude exploratoire
2000
Our objective is to encourage the human-computer interface designers to be more interested in the uses made of their product by taking into account to a higher degree the human-factor in the testing phase which often is too focused on technical aspects. We want to facilitate the integration of the user as a source of evaluation during the testing phase. Our aim is to offer the designer a software environment of practical tests that allow them to have their own products evaluated by their users. We undertook an experiment to explore the feasibility of this project.
Brak sprzeczności planu miejscowego ze studium jako jedna z zasad sporządzania planu miejscowego
2022
Zagadnienie relacji między miejscowym planem zagospodarowania przestrzennego a studium uwarunkowań i kierunków zagospodarowania przestrzennego gminy stanowi przedmiot wieloletnich badań przedstawicieli nauki prawa, a także obszernych wypowiedzi sformułowanych w orzecznictwie. Wymóg, by plan miejscowy nie naruszał ustaleń studium, jest wymogiem ustawowym zawartym w przepisach art. 20 ust. 1 w zw. z art. 9 ust. 4 i art. 15 ust. 1 ustawy o planowaniu i zagospodarowaniu przestrzennym. Okoliczność, że w dalszym ciągu dochodzi do unieważnienia uchwał planistycznych w całości lub w części z powodu sprzeczności ze studium, wskazuje na aktualność tej problematyki oraz potrzebę dalszego popularyzowan…
Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry
2021
The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiological (e.g., signaling) and pathological (e.g., oxidative stress) states. This PTM typically maps at multiple protein sites, generating a heterogeneous population of proteoforms with specific biophysical and biochemical properties. The identification and quantitation of the variety of oxidized proteoforms originated under a given condition is required to assess the exact molecular nature of the species responsible for the process under investigation…