Search results for " vol"

showing 10 items of 3179 documents

The mediating effect of self-efficacy on the relationship between health locus of control and life satisfaction: A moderator role of movement disabil…

2019

Abstract Background Self-efficacy and health locus of control are widely recognized as psychological factors related to life satisfaction. However, little is known about the mechanisms of the decrease in life satisfaction in disabled people. Objective/Hypothesis The aim of the present study was to clarify the relationship between health locus of control (HLOC) and life satisfaction in people with acquired mobility impairment in comparison to a non-disabled sample, and to specify how self-efficacy interacts with these components. We hypothesized that self-efficacy is a mediator between HLOC and life satisfaction, and that disability moderates this relationship. Methods The cross-sectional st…

AdultMaleAdolescentDisabled peoplePersonal SatisfactionYoung Adult03 medical and health sciences0302 clinical medicineHumansDisabled Persons030212 general & internal medicineSelf-efficacyMovement DisordersPublic Health Environmental and Occupational HealthLife satisfactionGeneral MedicineMiddle AgedModerationHealthy VolunteersSelf EfficacyCross-Sectional StudiesLocus of controlScale (social sciences)Quality of LifeFemaleConstruct (philosophy)PsychologyAttitude to Health030217 neurology & neurosurgeryClinical psychologyDisability and Health Journal
researchProduct

Translocations Disrupting PHF21A in the Potocki-Shaffer-Syndrome Region Are Associated with Intellectual Disability and Craniofacial Anomalies

2012

Contains fulltext : 110038.pdf (Publisher’s version ) (Closed access) Potocki-Shaffer syndrome (PSS) is a contiguous gene disorder due to the interstitial deletion of band p11.2 of chromosome 11 and is characterized by multiple exostoses, parietal foramina, intellectual disability (ID), and craniofacial anomalies (CFAs). Despite the identification of individual genes responsible for multiple exostoses and parietal foramina in PSS, the identity of the gene(s) associated with the ID and CFA phenotypes has remained elusive. Through characterization of independent subjects with balanced translocations and supportive comparative deletion mapping of PSS subjects, we have uncovered evidence that t…

AdultMaleAdolescentGenotypePotocki–Shaffer syndromeChromosome DisordersHaploinsufficiencyBiologyHistone DeacetylasesSodium ChannelsTranslocation GeneticArticleChromatin remodelingCraniofacial Abnormalities03 medical and health sciencesSCN3A0302 clinical medicineIntellectual DisabilityNAV1.3 Voltage-Gated Sodium ChannelmedicineTranscriptional regulationGeneticsAnimalsHumansDeletion mappingGenetics(clinical)CraniofacialZebrafishGenetics (clinical)030304 developmental biologyGenetics0303 health sciencesChromosomes Human Pair 11Infant Newbornmedicine.diseaseGenetics and epigenetic pathways of disease DCN MP - Plasticity and memory [NCMLS 6]Child PreschoolHomeoboxFemaleChromosome DeletionHaploinsufficiencyExostoses Multiple Hereditary030217 neurology & neurosurgeryThe American Journal of Human Genetics
researchProduct

Optical noninvasive monitoring of skin blood pulsations

2005

Time-resolved detection and analysis of skin backscattered optical signals (remission photoplethysmography or PPG) provide rich information on skin blood volume pulsations and can serve for reliable cardiovascular assessment. Single- and multiple-channel PPG concepts are discussed. Simultaneous data flow from several locations on the human body allows us to study heartbeat pulse-wave propagation in real time and to evaluate vascular resistance. Portable single-, dual-, and four-channel PPG monitoring devices with special software have been designed for real-time data acquisition and processing. The prototype devices have been clinically studied, and their potential for monitoring heart arrh…

AdultMaleAdolescentHeartbeatMaterials Science (miscellaneous)Pulsatile flowArterial Occlusive DiseasesBlood volumeSensitivity and SpecificityIndustrial and Manufacturing EngineeringOpticsData acquisitionArterial occlusionsHeart RatePhotoplethysmogrammedicineAnimalsHumansDiagnosis Computer-AssistedBusiness and International ManagementPhotoplethysmographySkinFrequency filteringbusiness.industryReproducibility of ResultsEquipment DesignEquipment Failure Analysismedicine.anatomical_structurePulsatile FlowVascular resistanceFemalesense organsbusinessAlgorithmsBlood Flow VelocityBiomedical engineeringApplied Optics
researchProduct

Momentary Affect Predicts Bodily Movement in Daily Life: An Ambulatory Monitoring Study

2010

There is converging evidence that physical activity influences affective states. It has been found that aerobic exercise programs can significantly diminish negative affect. Moreover, among healthy individuals, moderate levels of physical activity seem to increase energetic arousal and positive affect. However, the predictive utility of affective states for bodily movement has rarely been investigated. In this study, we examined whether momentarily assessed affect is associated with bodily movement in everyday life. Using a previously published data set (Schwerdtfeger, Eberhardt, & Chmitorz, 2008), we reanalyzed 12-hr ecological momentary assessment (EMA) data from 124 healthy volunteer…

AdultMaleAdolescentMovementPhysical activityMonitoring AmbulatoryMotor ActivityAffect (psychology)Developmental psychologyYoung AdultPredictive Value of TestsReference ValuesSurveys and QuestionnairesActivities of Daily LivingHealthy volunteersHumansAerobic exerciseEveryday lifeEnergetic arousalApplied PsychologyAgedMovement (music)Middle AgedAffectComputers HandheldAmbulatoryFemalePsychologyJournal of Sport and Exercise Psychology
researchProduct

Comparison between once a day vs twice a day G-CSF for mobilization of peripheral blood progenitor cells (PBPC) in normal donors for allogeneic PBPC …

1998

Despite the wide use of G-CSF for mobilization of PBPC the best dose and schedule of G-CSF has not been definitively established. In this study we have compared three different schedules of G-CSF for mobilization of PBPC in normal donors including a single daily dose of 10 microg/kg/day for 5 days (21 donors) and doses of 6 (21 donors) or 8 microg/kg/12 h (6 donors) for 5 days. We demonstrate that G-CSF at doses of 6 and 8 microg/kg/12 h mobilizes significantly more CD34+ cells/ml of blood (83.3 +/- 6.7 and 121 +/- 6.9, respectively) than 10 microg/kg/day (71.6 +/- 6.5). Mobilization with 6 or 8 microg/kg/12 h of G-CSF was also associated with collection of significantly more CD34+ cells in…

AdultMaleAdolescentmedicine.medical_treatmentBlood volumeHematopoietic stem cell transplantationDrug Administration ScheduleAndrologyGranulocyte Colony-Stimulating FactorHumansTransplantation HomologousMedicinePlateletProgenitor cellChildAgedTransplantationMobilizationbusiness.industryHematopoietic Stem Cell TransplantationHematologyMiddle AgedHematopoietic Stem Cell MobilizationBlood Cell CountGranulocyte colony-stimulating factorTransplantationmedicine.anatomical_structureImmunologyBlood Component RemovalFemaleBone marrowbusinessBone Marrow Transplantation
researchProduct

Association between reduced lymphocyte beta-adrenergic receptors and left ventricular dysfunction in young obese subjects

1994

This study was designed to evaluate total (t) and surface (s) beta-adrenergic receptors (BAR) density and their relationships with left ventricular function in young obese subjects. BAR density, plasma insulin, catecholamines and left ventricular function were evaluated in 27 young obese subjects (BMI30.5 kg/m2 for males and27.3 kg/m2 for females) without other risk factors for cardiovascular diseases (smoking, hypertension, diabetes and lipid abnormalities) and in 20 lean controls (BMI25 kg/m2 for males and24.7 kg/m2 for females). Both groups were matched for gender, age and body height. BAR density was evaluated according to Böyum and De Blasi methods. Plasma catecholamines by high perfus…

AdultMaleAgingSettore MED/09 - Medicina InternaRadioimmunoassayPeripheral obesity Central Obesity lymphocyte beta adrenergic receptors left ventricular functionStroke VolumeSettore MED/11 - Malattie Dell'Apparato CardiovascolareVentricular Function LeftCatecholaminesEchocardiographyReceptors Adrenergic betaHumansInsulinRegression AnalysisFemaleLymphocytesObesityCardiac OutputRadionuclide AngiographyChromatography High Pressure Liquid
researchProduct

Virtual reality versus computer-aided exposure treatments for fear of flying

2011

Evidence is growing that two modalities of computer-based exposure therapies—virtual reality and computer-aided psychotherapy—are effective in treating anxiety disorders, including fear of flying. However, they have not yet been directly compared. The aim of this study was to analyze the efficacy of three computer-based exposure treatments for fear of flying: virtual reality exposure therapy (VRET), computer-aided exposure with a therapist’s (CAE-T) assistance throughout exposure sessions, and self-administered computer-aided exposure (CAE-SA). A total of 60 participants with flying phobia were randomly assigned to VRET, CAE-T, or CAE-SA. Results indicate that the three interventions were …

AdultMaleAircraftPsychological interventionImplosive TherapyFlying PhobiaStatistics NonparametricVirtual realitylaw.inventionExposureFear of flyingVirtual Reality Exposure TherapyUser-Computer InterfaceArts and Humanities (miscellaneous)Randomized controlled trialFear of flyinglawDevelopmental and Educational PsychologymedicineHumansComputer SimulationAnalysis of VarianceIntention-to-treat analysisModalitiesfungiPor a volar--Tractament--Simulació per ordinadorFearMiddle Agedmedicine.diseaseFear of flying --Treatment--Computer simulationIntention to Treat AnalysisTreatmentClinical PsychologyTreatment OutcomePhobic DisordersComputer-aidedPatient SatisfactionRandomized controlled trialTherapy Computer-AssistedAnxietyFemalemedicine.symptomPsychologyClinical psychology
researchProduct

Mandibular connective tissue pedicle flaps in implant dentistry: report of three cases.

2007

Abstract An increase in soft tissues and alveolar bone in the anterior mandibular area between the canines is necessary to achieve a good esthetic result. The present article describes a technique for gaining bone volume and soft tissue to cover bone defects that would otherwise compromise the final result of prosthetic implant restoration in the anterior mandible. Three patients with anterior mandibular atrophy caused by loss of the mandibular incisors are presented. Particulate autologous bone grafting, the raising of a pediculate connective tissue flap to increase soft tissue, and implant placement were carried out simultaneously. After 2 years of follow-up, the implants were in good cli…

AdultMaleAlveolar Bone LossGingivaDentistryConnective tissueMandibleEsthetics DentalTransplantation AutologousSurgical FlapsAtrophyOsseointegrationmedicineHumansDental alveolusOrthodonticsDental ImplantsBone TransplantationImplant dentistrybusiness.industryMandibleSoft tissueAlveolar Ridge AugmentationMiddle Agedmedicine.diseaseIncisormedicine.anatomical_structureConnective TissueFemaleImplantOral SurgeryAtrophybusinessBone volumeFollow-Up StudiesThe Journal of oral implantology
researchProduct

The Influence of Chitosan on the Oral Bioavailability of Acyclovir-a Comparative Bioavailability Study in Humans

2015

Purpose The effects of chitosan hydrochloride on the oral absorption of acyclovir in humans were studied to confirm the absorption enhancing effects reported for in vitro and rat studies, respectively. Methods A controlled, open-label, randomized, 3-phase study was conducted in 12 healthy human volunteers. Zovirax 200 mg dispersible tablets co-administered with doses of 400 and 1000 mg chitosan HCl were compared with Zovirax only. Results The expected increased absorption of acyclovir was not observed. On the contrary, mean area under the plasma concentration-time curve (AUC0-12 h) and maximal plasma concentration (Cmax) decreased following concomitant chitosan intake (1402 versus 1017 and …

AdultMaleBioavailability StudyAcyclovirAdministration OralBiological AvailabilityPharmaceutical Science02 engineering and technologyAbsorption (skin)PharmacologyAntiviral Agents030226 pharmacology & pharmacyHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]Chitosan03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticsbiopharmaceutics classification systemHumansMedicinePharmacology (medical)Chromatography High Pressure LiquidPharmacologyChitosanDrug Carriersbusiness.industryOrganic Chemistry021001 nanoscience & nanotechnologyBiopharmaceutics Classification SystembiowaiverHealthy Volunteers3. Good healthBioavailabilitychemistryexcipient interactionsData Interpretation StatisticalMolecular MedicineFemaleChitosan hydrochloridebioavailability0210 nano-technologybusinesspharmacokineticsResearch PaperBiotechnologyBiological availabilityPharmaceutical Research
researchProduct

Differential contributions of ankle plantarflexors during submaximal isometric muscle action: A PET and EMG study

2014

Abstract The objective of this study was to investigate the relative contributions of superficial and deep ankle plantarflexors during repetitive submaximal isometric contractions using surface electromyography (SEMG) and positron emission tomography (PET). Myoelectric signals were obtained from twelve healthy volunteers (27.3±4.2yrs). A tracer ([ 18 F]-FDG) was injected during the exercise and PET scanning was done immediately afterwards. The examined muscles included soleus (Sol), medial gastrocnemius (MG), lateral gastrocnemius (LG), and flexor hallucis longus (FHL). It was found that isometric maximal voluntary contraction (MVC) force, muscle glucose uptake (GU) rate, and SEMG of variou…

AdultMaleBiophysicsNeuroscience (miscellaneous)Isometric exerciseElectromyographyYoung AdultMuscle actionIsometric ContractionHealthy volunteersmedicineHumansExercise physiologyMuscle Skeletalta315ExerciseLegArthrometry Articularmedicine.diagnostic_testElectromyographybusiness.industryBiomechanicsAnatomymusculoskeletal systemMagnetic Resonance ImagingHealthy VolunteersGlucosemedicine.anatomical_structureFlexor hallucis longusPositron-Emission TomographyFemaleNeurology (clinical)AnkleAnklebusinessNuclear medicineJournal of Electromyography and Kinesiology
researchProduct