Search results for "(2)-2"
showing 10 items of 170 documents
Gene-environment interactions of CETP gene variation in a high cardiovascular risk Mediterranean population
2010
Genome-wide association studies show that cholesteryl ester transfer protein (CETP) single nucleotide polymorphisms (SNPs) are more strongly associated with HDL cholesterol (HDL-C) concentrations than any other loci across the genome. However, gene-environment interactions for clinical applications are still largely unknown. We studied gene-environment interactions between CETP SNPs and dietary fat intake, adherence to the Mediterranean diet, alcohol consumption, smoking, obesity, and diabetes on HDL-C in 4,210 high cardiovascular risk subjects from a Mediterranean population. We focused on the −4,502C>T and the TaqIB SNPs in partial linkage disequilibrium (D'= 0.88; P < 0.001). They were i…
Prenatal exposure to the CB1 receptor agonist WIN 55,212-2 causes learning disruption associated with impaired cortical NMDA receptor function and em…
2005
The aim of this study was to investigate whether prenatal exposure to the cannabinoid CB1 receptor agonist WIN 55,212-2 (WIN) at a daily dose devoid of overt signs of toxicity and/or gross malformations (0.5 mg/kg, gestation days 5-20), influences cortical glutamatergic neurotransmission, learning and emotional reactivity in rat offspring. Basal and K+-evoked extracellular glutamate levels were significantly lower in cortical cell cultures obtained from pups exposed to WIN during gestation with respect to those measured in cultures obtained from neonates born from vehicle-treated dams. The addition of NMDA to cortical cell cultures from neonates born from vehicle-treated dams concentration-…
Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice
2017
Chronic cannabinoid consumption is an increasingly common behavior among teenagers and has been shown to cause long-lasting neurobehavioral alterations. Besides, it has been demonstrated that cocaine addiction in adulthood is highly correlated with cannabis abuse during adolescence. Cocaine consumption and subsequent abstinence from it can cause psychiatric symptoms, such as psychosis, cognitive impairment, anxiety, and depression. The aim of the present research was to study the consequences of adolescent exposure to cannabis on the psychiatric-like effects promoted by cocaine withdrawal in adult mice. We pre-treated juvenile mice with the cannabinoid CB1 receptor agonist WIN 55212-2 (WIN)…
The effect of cannabinoid receptor agonist WIN 55,212-2 on anxiety-like behavior and locomotion in a genetic model of absence seizures in the elevate…
2022
GAERS and NEC rats were treated with cannabinoid 1/2 receptor agonist WIN 55,212-2 2 mg/kg and tested on the Elevated Plus-Maze
Zvaigžņotā Debess: 2009, Pavasaris (203)
2009
Contents: E.R.Mustel, President of the Astronomical Council of the USSR Academy of Sciences. Congratulations to Editorial Board of “Zvaigžņotā debess” ; Z.Alksne. Gould’s Belt ; I.Daube. At the Radioastrophysical Observatory of the Latvian Academy of Sciences ; Z.Alksne, A.Alksnis. Lopsided Galaxies ; A.Alksnis. HII Region Gum 29 – a Stellar Nursery ; D.Docenko. On Collision of Asteroid 2008 TC3 with the Earth ; V.Lapoška. On „Leap Second” ; I.Vilks, M.Gills. Beginning of the International Year of Astronomy in Paris: Impressions by Latvian Delegates ; J.Jaunbergs. Equatorial Ridge on Iapetus ; M.Sudārs. Space Shuttle Is Not Likely to Retire Next Year ; I.Vilks. Planet Satellite Names in Lat…
"Table 53" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."
2004
Event shape means.
CCDC 291811: Experimental Crystal Structure Determination
2006
Related Article: F.A.Cotton, C.A.Murillo, S.-E.Stiriba, Xiaoping Wang, Rongmin Yu|2005|Inorg.Chem.|44|8223|doi:10.1021/ic051282c
CCDC 837170: Experimental Crystal Structure Determination
2012
Related Article: J.Martinez-Lillo, D.Armentano, G.De Munno, J.Cano, F.Lloret, M.Julve, J.Faus|2011|Inorg.Chem.|50|12405|doi:10.1021/ic202088s
CCDC 294202: Experimental Crystal Structure Determination
2012
Related Article: F.S.Delgado, C.A.Jimenez, P.Lorenzo-Luis, J.Pasan, O.Fabelo, L.Canadillas-Delgado, F.Lloret, M.Julve, C.Ruiz-Perez|2012|Cryst.Growth Des.|12|599|doi:10.1021/cg200675u
CCDC 903510: Experimental Crystal Structure Determination
2013
Related Article: Antti Riisio, Ari Lehtonen, Mikko M. Hanninen, Reijo Sillanpaa|2013|Eur.J.Inorg.Chem.||1499|doi:10.1002/ejic.201201234