Search results for "(ERP)"

Colonization of adrenal glands and ovaries of mice by variants of HSV 1 and 2

1991

The herpes simplex virus (HSV)-infected mouse model was used to correlate histopathological lesions in adrenal glands and ovaries with the localisation of viral nucleic acids and viral antigens, employing in situ hybridization and immunohistochemistry. In the adrenals, the lesions were mainly restricted to the zona fasciculata and the zona reticularis, sometimes extending to the medulla. In the ovaries, lesions were detected in follicles and in the stroma. During the course of infection, HSV nucleic acids could be detected earlier than HSV proteins. Next to the center of necrotic foci mainly HSV proteins were detected, whereas peripheral cells were found to contain viral nucleic acids. In s…

Quantitative microscopy reveals stepwise alteration of chromatin structure during herpesvirus infection

2019

During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm. We have shown previously that HSV-1 infection induces the formation of channels through the compacted peripheral chromatin. Here, we used three-dimensional confocal and expansion microscopy, soft X-ray tomography, electron microscopy, and random walk simulations to analyze the kinetics of host chromatin redistribution and capsid localization relative to their egress site at the nuclear envelope. Our data demonstrated a gradual increase in chromatin marginalization, and the kinetics of chromatin smoothening arou…

Antiviral prophylaxis in patients with haematological malignancies and solid tumours: Guidelines of the Infectious Diseases Working Party (AGIHO) of …

2006

Morbidity and mortality in patients with malignancies are increased by viral infections. These mostly are reactivations of asymptomatic latent infections. They primarily concern clinical entities associated with the reactivation of herpes viruses, such as varicella zoster virus (VZV) and cytomegalovirus (CMV). Respiratory tract infections caused by influenza, parainfluenza or respiratory syncytial virus (RSV) are less common. Since reactivation of latent infections has major clinical impact, antiviral prophylaxis is an attractive approach for patients expecting immunosuppression. The main risk factor for clinically relevant reactivation is profound disruption of cellular immune response. Du…

Enhancement by TNF-alpha of reactivation and replication of latent herpes simplex virus from trigeminal ganglia of mice.

1995

The influence of tumor-necrosis-factor-alpha (TNF-alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukine-1 (IL-1) and IL-3 on the in vitro reactivation frequency and replication rate of trigeminal ganglia of mice latently infected with herpes simplex virus (HSV) strain KOS was studied. It could be demonstrated that TNF-alpha and possibility GM-CSF, but not IL-1 and IL-3, enhanced the reactivation frequency and replication of HSV. Interferon alpha/beta (IFN alpha/beta) prevented reactivation and replication.

Turystyczny przewodnik po Piekle Mikołaja Reja, czyli o międzyplanetarnych podróżach duszy ludzkiej

2020

The article deals with the complex issue of presenting the underworld in the Reja's Wizerunk. The author draws attention to the presence in the output of the old Polish poet of many visionary elements borrowed from the most varied traditions and religious systems. The popular pattern of searching for spiritual perfection, fixed in the archetype of the topographic movement of the hero (Latin: Homo viator) turns out to be particularly visible. It turns out that at the very foundations of this imaginative pattern there is an ancient doctrine or interplanetary wandering of the soul. Most of the work was focused on the description of XI songs of Reja’s WizerunV, where a description of hell appea…

不同情绪面孔的视觉工作记忆表现差异 [The Performance Difference of Visual Working Memory between Various Emotional Faces]

2022

Among social-emotional stimuli, emotional faces occupy an important position, which specifically refer to human faces with certain facial expressions. The visual working memory is a limited workspace where information can be saved online and can be accessed and operated by advanced cognitive function during the maintenance period. A large number of behavioral and electrophysiological studies have shown that there are differences in visual working memory performance of different emotional faces. Specifically, angry faces can enhance the visual working memory performance; fearful faces may cause some damage to visual working memory; sad faces will impair face recognition encoding in visual wo…

An Upper Mississippian echinoderm microfauna from the Genicera Formation of northern León (Carboniferous, Cantabrian Mountains, N Spain)

2020

For the first time an echinoderm microfauna is recorded from the cephalopod limestone facies (‘griotte facies’) of the lower Carboniferous (Mississippian) Genicera Fm. (Alba Fm.). The formation is widespread in the Cantabrian Mountains in NW Spain, but the ossicles are from some sections in the surroundings of the Bernesga valley in northern León. They have been derived from insoluble acetic acid residues from samples of the upper and especially of the uppermost part of the formation (Canalón Mb. and Millaró Beds). The microfauna include taxonomically treated wheel-shaped ossicles, sieve-plates and rods of holothurians, goniodonts of ophiocistioids, and ophiuroid and stenuroid skeletal elem…

Brevi note in margine al caso Englaro: a proposito di interpretazione "giurisprudenziale" e di dimensione storico-sociale del diritto

2009

Impresionisma ainavu attēloto laikapstākļu un diennakts apgaismojuma maiņas analīze vizuālajā mākslā 5.-8. klasē

2022

Bakalaura darba tēma: Impresionisma ainavu attēloto laikapstākļu un diennakts apgaismojuma maiņas analīze vizuālajā mākslā 5.-8. klasē. Darba mērķis: izpētīt impresionisma ainavu attēloto laikapstākļu un diennakts apgaismojuma maiņu vizuālajā mākslā 5.-8. klasē. Darba ietvaros būs izstrādāti radošie uzdevumi 5.-8. klasei, kas paredzēti uzstādītas tēmas apguvi. Darbs tiek strukturēts 8 nodaļās. Pirmajā nodaļā izklāstas Impresionisma virziena pamatnostādnes, raksturojošās iezīmes un ainavas kā mākslas žanra nozīmīgums Impresionisma virzienā. Otrajā nodaļā analizētas mākslas darbu izpētes metodes. Trešajā nodaļā definēts interpretācijas process mākslā, tas nozīmīgums un pielietojums. Ceturtajā…

Focusing on Workplace Communication

2019

Communication has a constitutive role in the workplace; in workplace communication the organization comes into being. In workplace communication workers create and negotiate meanings and a shared understanding of important work-related issues. Communication is also essential for a functional working environment. Especially in knowledge-based work members of the workplace aim at success, efficiency, and productivity by discussing, conversing, debating, and providing and receiving feedback. Hence, when striving to establish a healthy workplace with high levels of satisfaction and well-being, one has to understand the dynamics of workplace communication. This chapter examines interpersonal com…