Search results for "-Ag"
showing 10 items of 514 documents
Is the beta3-adrenoceptor (ADRB3) a potential target for uterorelaxant drugs?
2007
International audience; The management of premature birth still remains unsatisfactory. Since the relative lack of efficiency and/or safety of current tocolytic agents have been highlighted, it is necessary to develop new uterorelaxant drugs deprived of important maternal and foetal side effects. Our work reported in this review focuses on a potential new target for tocolytic drugs, the beta3-adrenoceptor (ADRB3). This third type of ADRB is shown to be present and functional in human myometrium. We demonstrated that ADRB3 agonists are able to inhibit in-vitro spontaneous contractions of myometrial strips, via a cyclic AMP-mediated pathway. Furthermore, we established that ADRB3 is the predo…
A MAS Security Framework Implementing Reputation Based Policies and Owners Access Control
2006
Multi-agent systems expose users to risks related to lack of knowledge above interacting users. Such systems should provide tools to protect their own resources from illegal accesses by unauthorized users. This paper describes a security framework for Multi-agent systems preventing a trusted agent to interact with malicious agents and granting agent and platform resources. This feature is obtained adding an access control mechanism that joins the benefits of Credential Based Access Control, Role Based Access Control and Mandatory Access Control. Authorizations and access control policies are set by XML based policy files. A case study on a distributed document retrieval system is also illus…
Distributed Cognition Learning in Collaborative Civil Engineering Projects Management
2012
Due to the diversity and complexity of its projects, the Civil Engineering domain has historically encompassed very heterogeneous disciplines. From the beginning, any Civil Infrastructure project is systematically divided into smaller subprojects in order to reduce or isolate the overall complexity. However, as a parallel design work, these subdesigns may experience divergences which often lead to design conflicts when they are merged back to the global design. If a high-quality design is desired, these conflicts need to be detected and solved.We present a Multiagent system able to manage these design conflicts by detecting them, by assisting the engineers in the negotiation of solutions, a…
Exploiting Deductive Processes for Automated Network Management
2005
This paper focuses on improving network management by the adoption of artificial intelligence techniques. We propose a distributed multiagent architecture for network management, which exploits the dynamic reasoning capabilities of the situation calculus in order to emulate the reactive behavior of a human expert to fault situations. The information related to network events is generated by programmable sensors deployed on the network devices and is collected by a logical entity for network managing where it is merged with general domain knowledge, with a view to identifying the root causes of faults and to decide on reparative actions. The logical inference system has been devised to carry…
Pharmacological and biochemical study on the effects of selective phosphodiesterase inhibitors on human term myometrium
1999
This study was aimed at evaluating the in vitro effects of phosphodiesterase inhibitors and beta2-adrenoceptor agonists on spontaneous contractions of human term myometrium. Rolipram, RP 73401 (3-cyclopentyloxy-N-(3,5(-dichloro-4-pyridil)-4-methoxybenzamide) and Ro 20-1724 (1-4-(3-butoxy-4-methoxybenzyl)-2-imidozolidinone) (phosphodiesterase 4 inhibitors) inhibited spontaneous myometrial contractions (Emax approximately 100%; pD2 of 6.80+/-0.28, 6.84+/-0.32 and 6.31+/-0.03, respectively). Salbutamol and formoterol were less effective (Emax=40+/-6% and 35+/-12%, respectively) than phosphodiesterase 4 inhibitors to reduce myometrial contractility. Inhibitors of phosphodiesterase 3 (milrinone …
Affine Surfaces With a Huge Group of Automorphisms
2013
We describe a family of rational affine surfaces S with huge groups of automorphisms in the following sense: the normal subgroup Aut(S)alg of Aut(S) generated by all algebraic subgroups of Aut(S) is not generated by any countable family of such subgroups, and the quotient Aut(S)/Aut(S)alg cointains a free group over an uncountable set of generators.
Study of isomeric states in $^{198,200,202,206}$Pb and $^{206}$Hg populated in fragmentation reactions
2018
International audience; Isomeric states in isotopes in the vicinity of doubly-magic 208Pb were populatedfollowing reactions of a relativistic 208Pb primary beam impinging on a9Be fragmentation target. Secondary beams of 198,200,202,206Pb and 206Hg wereisotopically separated and implanted in a passive stopper positioned in thefocal plane of the GSI Fragment Separator. Delayed γ rays were detected withthe Advanced Gamma Tracking Array (AGATA). Decay schemes were reevaluatedand interpreted with shell-model calculations. The momentumdependentpopulation of isomeric states in the two-nucleon hole nuclei206Pb/206Hg was found to differ from the population of multi neutron-holeisomeric states in 198…
A novel approach to measure the cross section of the 18O(p, α)15N resonant reaction in the 0-200 keV energy range
2009
The 18O(p, ?)15N reaction is of primary importance to pin down the uncertainties, due to nuclear physics input, affecting present-day models of asymptotic giant branch stars. Its reaction rate can modify both fluorine nucleosynthesis inside such stars and oxygen and nitrogen isotopic ratios, which allow one to constrain the proposed astrophysical scenarios. Thus, an indirect measurement of the low-energy region of the 18O(p, ?)15N reaction has been performed to access, for the first time, the range of relevance for astrophysical application. In particular, a full, high-accuracy spectroscopic study of the 20 and 90 keV resonances has been performed and the strengths deduced to evaluate the r…
Patterns Reuse in the PASSI methodology
2003
Design patterns already proved successful in lowering the development time and number of errors of object-oriented software; now, they are, candidate to play a similar role in the MAS (multi-agent system) context. In this work we describe our experiences in the identification, production and application of patterns for agents. Some patterns are described together with the classification criteria and documentation approach we adopt. Upon them, we base a pattern reuse process that can be considered one of the distinguishing elements of the design methodology (PASSI) we use to develop MAS. Patterns can be applied to an existing agent or used to produce a new one with the support of a specific …
A Rule-Based Multi-agent System for Road Traffic Management
2009
Road Traffic presents a high dynamism which makes necessary the development of traffic management and control strategies to improve traffic flows and more important, road safety. This dynamism makes necessary the use of intelligent systems to support traffic organizations and road operators to cope with incidents. In this paper we introduce a new expert system to support traffic management when weather problems occur in the road network. The system uses multiagent technology to work with the specific characteristics of traffic domain and is able to work in two modes: a) coordinately, where all the agents works to solve problems in large networks and b) locally where due to communications pr…