Search results for "-PEA"
showing 7 items of 7 documents
Viral replication modes in single-peak fitness landscapes: A dynamical systems analysis
2017
Positive-sense, single-stranded RNA viruses are important pathogens infecting almost all types of organisms. Experimental evidence from distributions of mutations and from viral RNA amplification suggest that these pathogens may follow different RNA replication modes, ranging from the stamping machine replication (SMR) to the geometric replication (GR) mode. Although previous theoretical work has focused on the evolutionary dynamics of RNA viruses amplifying their genomes with different strategies, little is known in terms of the bifurcations and transitions involving the so-called error threshold (mutation-induced dominance of mutants) and lethal mutagenesis (extinction of all sequences du…
Low-Q peak in X-ray patterns of choline-phenylalanine and homophenylalanine: a combined effect of chain and stacking
2016
Abstract In this contribution we report for the first time the X-ray patterns of choline-phenylalanine and choline-homophenylalanine ionic liquids. The presence of a low Q peak in both systems is another evidence that a long alkyl chain is not always needed to establish a nanodomain segregation in the liquid sufficient to be revealed by the diffraction experiment. These new data are compared with the diffraction patterns and the theoretical calculations of other choline-aminoacid ionic liquids recently reported. A significant role might be played by the stacking interactions between aromatic rings.
Spasmolytic Effects of Aphanizomenon Flos Aquae (AFA) Extract on the Human Colon Contractility.
2021
The blue-green algae Aphanizomenon flos aquae (AFA), rich in beneficial nutrients, exerts various beneficial effects, acting in different organs including the gut. Klamin® is an AFA extract particularly rich in β-PEA, a trace-amine considered a neuromodulator in the central nervous system. To date, it is not clear if β-PEA exerts a role in the enteric nervous system. The aims of the present study were to investigate the effects induced by Klamin® on the human distal colon mechanical activity, to analyze the mechanism of action, and to verify a β-PEA involvement. The organ bath technique, RT-PCR, and immunohistochemistry (IHC) were used. Klamin® reduced, in a concentration-dependent manner, …
Influence of oblique edge blanking on the online punching quality after stretch bending
2018
The oblique edge punching was proposed to reduce the surrounding sag failure occurred under the large punching force during online punching after stretch bending. The finite element models under three different kinds of punches were stablished and the punching processes were simulated by using the DEFORM-3D software. Comparison between the flat-edge punch and the oblique edge punches were realized, and the optimal height of the oblique edge of the unilateral bevelled punch and the single-peak bevelled punch were obtained. Three kinds of punches were designed based on the simulation results, and the experiments for manufacturing the upper strip of the automobile door frame by the online punc…
Past and present role of the Indian-fig prickly-pear (Opuntia ficus-indica (L.) Miller, Cactaceae) in the agriculture of sicily
1992
Of prickly-pear cacti occurring in Sicily, the most widespread and economically important is Opuntia ficus-indica (L.) Miller. In Sicily it has, since its introduction, played an important role in the exploitation of marginal areas. The Sicilian experience is described with reference to the historical outlines and the present intensive production of late fruit. Information on historical and actual uses of the plant and its products (flowers, cladodes, fruits) is given.
Searches for heavy neutrinos from Z decays
1992
We have searched for possible fourth family heavy neutrinos, pair produced in Z0 decays, in a sample of about 112 000 hadronic Z0 final states collected with the DELPHI detector. For all mixing matrix elements we exclude a new Dirac neutrino lighter than 44.5 GeV at a 95% confidence level, if the neutrino couples to the electron or muon family, and lighter than 44.0 GeV, if the neutrino couples to the tau family. Depending on the values of the mixing element and to which lepton family the neutrino couples, we obtain mass limits up to 46.2 GeV. For all mixing matrix elements we exclude a new Majorana neutrino lighter than 39.0 GeV, if it couples to the electron or the muon family, and lighte…
Single- and Double-Strand Breaks of Dry DNA Exposed to Protons at Bragg-Peak Energies
2017
International audience; Ultrathin layers (<20 nm) of pBR322 plasmid DNA were deposited onto 2.5 μm thick polyester films and exposed to proton Bragg-peak energies (90–3000 keV) at various fluences. A quantitative analysis of radio-induced DNA damage is reported here in terms of single- and double-strand breaks (SSB and DSB, respectively). The corresponding yields as well as G-values and the cross sections exhibit fairly good agreement with the rare available data, stemming from close experimental conditions, namely, based on α particle irradiation. SSB/DSB rates appear to be linear when plotted against linear energy transfer (LET) in the whole energy range studied. All the data present a ma…