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showing 10 items of 9657 documents
Nonlinearities in plant RNA virus fitness
2012
Una de las mayores amenazas tanto para la salud humana y animal, como para la agronomía es la emergencia de nuevas enfermedades infecciosas, la mayoría de las cuales están causadas por los virus de RNA. La emergencia viral es un problema complejo que consista en la adquisición de la variación genética, por mutación o recombinación, dentro de la población viral en el huésped reservorio la cual podría facilitar la capacidad de infectar de manera eficiente nuevos huéspedes. Los virus de RNA presentan a una evolucionabilidad extraordinaria por sus grandes tamaños poblacionales, cortos tiempos de generación y altas tasas de mutación y recombinación. Comprender los mecanismos evolutivos que podrí…
Mouse models of cytomegalovirus latency: overview.
2002
Abstract Background: The molecular regulation of viral latency and reactivation is a central unsolved issue in the understanding of cytomegalovirus (CMV) biology. Like human CMV (hCMV), murine CMV (mCMV) can establish a latent infection in cells of the myeloid lineage. Since mCMV genome remains present in various organs after its clearance from hematopoietic cells first in bone marrow and much later in blood, there must exist one or more widely distributed cell type(s) representing the cellular site(s) of enduring mCMV latency in host tissues. Endothelial cells and histiocytes are candidates, but the question is not yet settled. Another long debated problem appears to be solved: mCMV establ…
Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells
2007
Baculovirus, Autographa californica multiple nucleopolyhedrovirus (AcMNPV), has the ability to transduce mammalian cell lines without replication. The general objective of this study was to detect the transcription and expression of viral immediate-early genes in human cells and to examine the interactions between viral components and subnuclear structures. Viral capsids were seen in large, discrete foci in nuclei of both dividing and non-dividing human cells. Concurrently, the transcription of viral immediate-early transregulator genes (ie-1, ie-2) and translation of IE-2 protein were detected. Quantitative microscopy imaging and analysis showed that virus transduction altered the size of …
On the Dynamics of Fractional Visco-Elastic Beams
2012
With increasing advanced manufacturing process, visco-elastic materials are very attractive for mitigation of vibrations, provided that you may have advanced studies for capturing the realistic behavior of such materials. Experimental verification of the visco-elastic behavior is limited to some well-known low order models as the Maxwell or Kelvin models. However, both models are not sufficient to model the visco-elastic behavior of real materials, since only the Maxwell type can capture the relaxation tests and the Kelvin the creep tests, respectively. Very recently, it has been stressed that the most suitable model for capturing the visco-elastic behavior is the spring-pot, characterized …
The ALICE experiment at the CERN LHC
2008
Journal of Instrumentation 3(08), S08002 (2008). doi:10.1088/1748-0221/3/08/S08002
Phenomenological description of the vortex density in rotating BEC superfluids
2008
The close analogy of a purely magnetic excitation scheme, used in the experiments on Bose-Einstein condensate by Hodby et al., and the rotating bucket experiments with liquid helium 4 has suggested us to apply a phenomenological equation for the vortex line density, previously proposed for rotating superfluid helium 4, to describe the vortex density in a rotating Bose-Einstein condensate as a function of the angular speed. In both systems, the phenomenological equation provides a reasonable description of the observed data.
Developing response-ability in human-wasp encounters
2023
Learning to live with unloved others is crucial in the ecological crisis. Unloved wasps are feared and disliked for their sting. Understanding of their ecological importance is increasing, however. Human-wasp encounters are changing with environmental changes, and strategies for multispecies cohabitation are needed. This multispecies study highlights features of wasp biology affecting human-wasp encounters and analyzes how conflicted human-wasp relations could be mitigated. The geographical focus is Finland, in the Northern boreal region. Biological analysis specified spatiotemporal aspects affecting human-wasp encounters: human and wasp habitats and preferences overlap ubiquitously. From a…
Work-family interface and psychological well-being : a personality and longitudinal perspective
2008
Tunne-elämältään tasapainoiset henkilöt kokevat muita harvemmin, että työ vie ajan perheeltä. Henkinen väsymys työssä ja parisuhteen ongelmat ennakoivat puolestaan psyykkistä pahoinvointia. Muun muassa nämä tulokset nousivat esiin Johanna Rantasen väitöstutkimuksessa, jossa hän tutki, onko yksilön persoonallisuudella merkitystä työn ja perheen yhteensovittamisen kannalta.Rantanen havaitsi, että persoonallisuuden piirteet: tunne-elämän tasapainoisuus, sovinnollisuus, tunnollisuus, ulospäinsuuntautuneisuus ja avoimuus uusille kokemuksille, ovat hyvin pysyviä yksilön ominaisuuksia aikuisuudessa. Ne ovat myös merkittäviä työn ja perheen yhteensovittamisen tuntemusten ennakoijia tilannetekijöide…
The Emotion Detectives Game: Supporting the Social-emotional Competence of Young Children
2017
The potential of digital games to enhance learning in different areas of child development has drawn increasing interest amid growing concern about children’s emotional well-being, social-emotional difficulties, and problem behaviors alongside diminishing economic resources for intervention and habilitation. However, digital games designed to promote social-emotional competence are surprisingly scarce. In this chapter, we explore children’s use of the digital game Emotion Detectives (ED), designed to promote children’s acquisition of emotional knowledge skills (e.g., recognizing, appreciating, and understanding emotions and their expressions), prosocial behaviors (e.g., helping, sharing, co…