Search results for "03 medical and health sciences"
showing 10 items of 33400 documents
Surrogacy relationships: a critical interpretative review
2020
Abstract Based on a critical interpretative review of existing qualitative research investigating accounts of ‘lived experience’ of surrogates and intended parents from a relational perspective, this article proposes a typology of surrogacy arrangements. The review is based on the analysis of 39 articles, which belong to a range of different disciplines (mostly sociology, social psychology, anthropology, ethnology, and gender studies). The number of interviews in each study range from as few as seven to over one hundred. Countries covered include Australia, Canada, Greece, India, Iran, Israel, Italy, Mexico, Norway, Russia, Sweden, UK, Ukraine, and the USA. Most studies focus only on surrog…
Kinetics of Renal Function during Induction in Newly Diagnosed Multiple Myeloma: Results of Two Prospective Studies by the German Myeloma Study Group…
2021
Background: Preservation of kidney function in newly diagnosed (ND) multiple myeloma (MM) helps to prevent excess toxicity. Patients (pts) from two prospective trials were analyzed, provided postinduction (PInd) restaging was performed. Pts received three cycles with bortezomib (btz), cyclophosphamide, and dexamethasone (dex
COMPRENSIÓN LECTORA Y ORAL: RELACIONES CON CI, GÉNERO Y RENDIMIENTO ACADÉMICO DE ESTUDIANTES DE EDUCACIÓN PRIMARIA READING AND ORAL COMPREHENSION: RE…
2016
ABSTRACTThe aim of this study was to investigate the relationship between reading and oral comprehension of primary school students, considering their IQ, their gender, and their academic performance. The students were enrolled in a state school located in the Valencian community where there are different linguistics programs, known as PIP and PIL. The Raven Test and the reading and oral comprehension Prolec-R tasks were provided. The academic performance of the students was also tested in the last term regarding the areas of Mathematics, Spanish and Science. The results showed statistically significant differences between the performance of reading and oral comprehension considering the IQ…
Rethinking validity in qualitative sport and exercise psychology research: a realist perspective
2019
Over the last two decades, the relativist approach has significantly shaped debates about the quality and rigour of qualitative research in sport and exercise psychology (SEP). In the absence of any published critiques of relativism in SEP, this paper problematises its central claims with a focus on the most recent contribution offered by Smith and McGannon (2018 Smith, B., & McGannon, K. R. (2018). Developing rigor in qualitative research: Problems and opportunities within sport and exercise psychology. International Review of Sport and Exercise Psychology, 11, 101–121. doi: 10.1080/1750984X.2017.1317357[Taylor & Francis Online], [Web of Science ®], , [Google Scholar]. Developing rigor in …
Aerosolization Performance of Jet Nebulizers and Biopharmaceutical Aspects
2019
In this work, 13 jet nebulizers, some of which in different configurations, were investigated in order to identify the biopharmaceutical constraints related to the quality attributes of the medicinal products, which affect their safety, efficiency, compliance, and effectiveness. The aerosolization parameters, including the aerosol output, aerosol output rate, mass median aerodynamic diameter, and fine particle fraction, were determined according to the European Standard EN 13544-1, using sodium fluoride as a reference formulation. A comparison between the aerosol output nebulization time and the fine particle fraction displayed a correlation between the aerosol quality and the nebulization …
The Unseen, the Discouraged, and the Outcast : Expressivity and the Foundations of Social Recognition
2018
AbstractThis article analyzes different pathologies of social affirmation and examines the grounds of social recognition from the point of view of the concept of expression. The red thread of the text is provided by Tove Jansson’s fictional works, and the focus will be on three cases in particular (the magic hat, the invisible girl and the figure of the Groke). The article sets out from the phenomenological distinction between the sensible expression, on the one hand, and the expressed content, on the other. By focusing on the three cases, the article distinguishes and analyses the fundamental structures of communal life and explicates different ways in which social affirmation can be one-s…
Retinal Vascular Assessment in Psoriasis: A Multicenter Study
2021
PurposeTo investigate the vascular status of the macula in psoriasis patients without history of ocular inflammation by Optical Coherence Tomography Angiography (OCTA).MethodsThis prospective cross-sectional multicenter study included 55 psoriasis patients and 55 control healthy subjects. A complete eye examination and 6 mm × 6 mm OCTA imaging were performed. Retinal vascular status was evaluated by analyzing vascular density (VD) of superficial vascular plexus (superficial wVD) and deep vascular plexuses (deep wVD) in a 6 mm × 6 mm area and in foveal (superficial fVD and deep fVD) and parafoveal sectors (superficial pVD and deep pVD). In addition, foveal thickness (FT) and foveal avascular…
Serum omega-3 fatty acids are not associated with age-related macular degeneration
2012
Revue non indexée dans le JCR.; International audience; Evaluation of: Kabasawa S, Mori K, Horie-Inoue K et al. Associations of cigarette smoking but. not serum fatty acids with age-related macular degeneration in a Japanese population. Ophthalmology 118(6), 1082–1088 (2011). Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly. in developed countries. Risk factors for AMD are classified into endogenous nonmodifiable. factors, including genetics and environmental factors such as smoking and dietary habits. Both. epidemiological and experimental studies suggest that dietary omega-3 long-chain fatty acids. would participate to prevent from the develo…
Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis
2019
Objective: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that mainly targets joints. Monocytes and macrophages are critical in RA pathogenesis and contribute to inflammatory lesions. These extremely plastic cells respond to extracellular signals which cause epigenomic changes that define their pathogenic phenotype. Here, we interrogated how DNA methylation alterations in RA monocytes are determined by extracellular signals. Methods: High-throughput DNA methylation analyses of patients with RA and controls and in vitro cytokine stimulation were used to investigate the underlying mechanisms behind DNA methylation alterations in RA as well as their relationship with clinic…
The Clinical Value of Autoantibodies in Rheumatoid Arthritis
2018
Rheumatoid arthritis (RA) is a highly heterogeneous syndrome in terms of clinical presentation, progression, and response to therapy. In such a complicated context, the identification of disease-related biomarkers would be undoubtedly helpful in assisting tailored approaches for every patient. Despite remarkable efforts, however, progress in new biomarker development and validation is dramatically slow. At present, none of the candidate genetic, cellular, or molecular biomarker has yet surpassed the clinical value of RA-specific autoantibodies, including rheumatoid factor (RF) and anti-citrullinated protein autoantibodies (ACPA). Rather, recent years have witnessed significant advancements …