Search results for "030221 ophthalmology & optometry"

showing 10 items of 565 documents

Optical coherence tomography of macular thickness after biaxial vs coaxial microincision clear corneal cataract surgery

2009

PURPOSE To evaluate macular thickness changes after biaxial microincision versus coaxial small incision cataract surgery using optical coherence tomography (OCT). METHODS This prospective, randomized, marked study comprised 70 patients (70 eyes) undergoing biaxial microincision surgery or conventional coaxial phacoemulsification. Patients were evaluated by Stratus OCT preoperatively and 1 day, 4 weeks, and 8 weeks postoperatively. Best-corrected visual acuity (BCVA), phacoemulsification power, and effective phacoemulsification time (EPT) were evaluated. RESULTS In the biaxial group, median foveal thickness changed from 160 microm preoperatively to 168 microm 8 weeks postoperatively (p=0.018…

AdultMaleMicrosurgerymedicine.medical_specialtyVisual acuitygenetic structuresmedicine.medical_treatmentVisual AcuityFoveal thicknessMacular EdemaCornea03 medical and health sciencesPostoperative Complications0302 clinical medicineOptical coherence tomographyOphthalmologyBlood-Retinal BarrierHumansMedicineMacula LuteaProspective StudiesIntraoperative ComplicationsAgedAged 80 and overPhacoemulsificationmedicine.diagnostic_testbusiness.industrySignificant differenceGeneral MedicinePhacoemulsificationMiddle AgedCataract surgeryeye diseasesOphthalmologySmall incision030221 ophthalmology & optometryFemalesense organsmedicine.symptomCoaxialbusinessTomography Optical Coherence030217 neurology & neurosurgeryEuropean Journal of Ophthalmology
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Effect of phenylephrine on static and dynamic accommodation

2018

Purpose We tested the hypothesis that changes in accommodation after instillation of Phenylephrine Hydrochloride (PHCl) observed in some studies could be caused by changes in optics. Methods We performed two experiments to test the effects of PHCl on static and on dynamic accommodation in 8 and 6 subjects, respectively. Objective wavefront measurements were recorded of the static accommodation response to a stimulus at different distances or dynamic accommodation response to a sinusoidally moving stimulus (between 1 and 3 D of accommodative demand at 0.2 Hz). The responses were characterized using two methods: one that takes into account the mydriatic optical effects on the accommodation pr…

AdultMaleOriginal articleAccommodationMydriaticsmedicine.medical_specialtygenetic structuresPhenylephrine03 medical and health sciences0302 clinical medicineCiliary bodyOphthalmologymedicineHumansAcomodaciónPhenylephrineMathematicsbusiness.industryCiliary BodyMétricaPupil sizeAccommodation OcularPhenylephrine Hydrochlorideeye diseasesCiliary musclemedicine.anatomical_structure030221 ophthalmology & optometryMetricsFemalesense organsbusinessFenilefrinaAccommodation030217 neurology & neurosurgeryOptometrymedicine.drugJournal of Optometry
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PREGO (presentation of Graves' orbitopathy) study: changes in referral patterns to European Group On Graves' Orbitopathy (EUGOGO) centres over the pe…

2015

BACKGROUND/AIMS: The epidemiology of Graves' orbitopathy (GO) may be changing. The aim of the study was to identify trends in presentation of GO to tertiary centres and initial management over time.METHODS: Prospective observational study of European Group On Graves' Orbitopathy (EUGOGO) centres. All new referrals with a diagnosis of GO over a 4-month period in 2012 were included. Clinical and demographic characteristics, referral timelines and initial decisions about management were recorded. The data were compared with a similar EUGOGO survey performed in 2000.RESULTS: The demographic characteristics of 269 patients studied in 2012 were similar to those collected in the year 2000, includi…

AdultMalePediatricsmedicine.medical_specialtyReferralEpidemiologyMedizin030209 endocrinology & metabolismGraves' ophthalmopathyTertiary Care Centers03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineEpidemiologymedicinePrevalenceHumansEpidemiology; Orbit; Ophthalmology; Sensory Systems; Cellular and Molecular NeuroscienceProspective StudiesProspective cohort studyReferral and Consultationbusiness.industryThyroid diseaseMiddle Agedmedicine.diseaseSensory SystemsEuropeGraves OphthalmopathyOphthalmologyCohort030221 ophthalmology & optometryObservational studyFemalesense organsPresentation (obstetrics)businessOrbitBritish journal of ophthalmology
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Risk factors for high myopia: a 22‐year follow‐up study from childhood to adulthood

2018

PURPOSE To determine the effect of the definition of high myopia on its prevalence and risk factors for high myopia. METHODS A total of 240 myopic schoolchildren (119 boys and 121 girls) at the mean age of 10.9 years (range 8.8-12.8 years) were recruited to a randomized clinical trial of myopia treatment among children from 3rd- and 5th grades of school referred for an eye examination due to poor distant vision and having no previous spectacles. Clinical follow-ups, including refraction with cycloplegia, were conducted annually at 3 years [third follow-up here = clinical follow-up 1, (n = 237)], and thereafter twice at approximately 10-year intervals [clinical follow-ups 2 (n = 179) and 3, …

AdultMalePediatricsmedicine.medical_specialtyYounger ageAdolescentgenetic structuresRefraction Ocularlaw.inventionYoung Adult03 medical and health sciences0302 clinical medicineRandomized controlled trialRisk FactorslawSurveys and QuestionnairesMyopiaPrevalencemedicineHumansChildFinlandRetrospective Studiesmedicine.diagnostic_testbusiness.industryVision TestsFollow up studiesHigh myopiaCycloplegiaGeneral MedicineOdds ratioeye diseasesOphthalmologyEyeglassesEye examinationCohortDisease Progression030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesForecastingActa Ophthalmologica
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Objective vs Subjective Vault Measurement After Myopic Implantable Collamer Lens Implantation

2009

PURPOSE: To evaluate the relationship between subjective measurements of vault and objective values measured with Visante optical coherence tomography (OCT) in eyes receiving an implantable contact lens (ICL) for myopia correction. DESIGN: Observational cross-sectional study. METHODS: SETTING: Fernández-Vega Ophthalmological Institute, Oviedo, Spain. PATIENTS: Four hundred and fifty-two eyes from 246 patients were elected to be implanted with a Visian ICL V4 (STAAR Surgical Inc, Monrovia, California, USA). OBSERVATION PROCEDURES: Subjective and objective measurements of vault after implantation of ICL. MAIN OUTCOME MEASURES: Subjective vault classified in 5 levels assessed using an optical …

AdultMalePhakic Intraocular Lensesmedicine.medical_specialtyRefractive errorBiometryAdolescentgenetic structuresEye diseasePhakic intraocular lensVision disorderYoung Adult03 medical and health sciences0302 clinical medicineLens Implantation IntraocularOphthalmologyLens CrystallineMyopiamedicineHumansBody Weights and MeasuresImplantable collamer lensScience & Technologybusiness.industryOutcome measuresMiddle Agedmedicine.diseaseeye diseasesOphthalmologyCross-Sectional StudiesVault (architecture)Implantable Contact Lens030221 ophthalmology & optometryOptometryFemalesense organsmedicine.symptombusinessTomography Optical Coherence030217 neurology & neurosurgeryAmerican Journal of Ophthalmology
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Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

2013

Refractive errors are common eye disorders of public health importance worldwide. Ocular axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia. We conducted a meta-analysis of genome-wide association studies for AL, combining 12,531 Europeans and 8,216 Asians. We identified eight genome-wide significant loci for AL (RSPO1, C3orf26, LAMA2, GJD2, ZNRF3, CD55, MIP, and ALPPL2) and confirmed one previously reported AL locus (ZC3H11B). Of the nine loci, five (LAMA2, GJD2, CD55, ALPPL2, and ZC3H11B) were associated with refraction in 18 independent cohorts (n = 23,591). Differential gene expression was observed for these loci in minus-lens-induced myopia mouse …

AdultMaleRefractive errorAdolescentGene ExpressionLocus (genetics)Genome-wide association studyBiologyOcular Axial LengthPolymorphism Single NucleotideWhite PeopleArticle03 medical and health sciences0302 clinical medicineAsian PeopleSDG 3 - Good Health and Well-beingmedicineGeneticsHumansGWASGenetic Predisposition to DiseaseGenetics(clinical)RSPO1Eye ProteinsGeneGenetics (clinical)030304 developmental biologyGenetic associationAgedGenetics0303 health sciencesta1184HeritabilityMiddle Agedta3121medicine.diseaseRefractive ErrorsAxial Length EyeGenetic Loci030221 ophthalmology & optometryEye disorderFemaleGenome-Wide Association StudySignal Transduction
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An alternative clinical routine for subjective refraction based on power vectors with trial frames.

2016

PURPOSE Subjective refraction determines the final point of refractive error assessment in most clinical environments and its foundations have remained unchanged for decades. The purpose of this paper is to compare the results obtained when monocular subjective refraction is assessed in trial frames by a new clinical procedure based on a pure power vector interpretation with conventional clinical refraction procedures. METHODS An alternative clinical routine is described that uses power vector interpretation with implementation in trial frames. Refractive error is determined in terms of: (i) the spherical equivalent (M component), and (ii) a pair of Jackson Crossed Cylinder lenses oriented …

AdultMaleRefractive errorCorrelation coefficientAdolescentVisual AcuityAstigmatismRefraction Ocular01 natural sciences010309 optics03 medical and health sciencesYoung Adult0302 clinical medicineOptics0103 physical sciencesmedicineHumansPhoropterMathematicsMonocularbusiness.industryOrientation (computer vision)Vision TestsEquipment Designmedicine.diseaseRefractive ErrorsSubjective refractionRefractionSensory SystemsOphthalmologyEyeglasses030221 ophthalmology & optometryFemalebusinessAlgorithmOptometryOphthalmicphysiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
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Results of an Adaptive Surgical Approach for Managing Late Onset Hypotony After Trabeculectomy With Mitomycin C.

2018

OBJECTIVES The objective of this study is to investigate the results of an adaptive approach of bleb revision surgery for late onset hypotony after trabeculectomy with mitomycin C because of bleb leakage and/or scleral melting. METHODS A total of 29 eyes of 27 patients, aged 63.8±11.7 years with hypotony maculopathy [intraocular pressure (IOP), ≤6 mm Hg] because of late onset bleb leakage and/or scleral melting after trabeculectomy with mitomycin C in which minimally invasive transconjunctival suturing of the scleral flap was impossible were enrolled in this retrospective interventional case series. External bleb leakage was seen in 16 eyes, 11 eyes suffered from scleral melting. Because of…

AdultMaleReoperationmedicine.medical_specialtyIntraocular pressureVisual acuitygenetic structuresmedicine.medical_treatmentMitomycinVisual AcuityGlaucomaOcular HypotensionTrabeculectomy03 medical and health sciencesTonometry Ocular0302 clinical medicineBlisterPostoperative ComplicationsOphthalmologyGlaucoma surgeryMedicineTrabeculectomyHumansIntraocular PressureAgedRetrospective StudiesAged 80 and overbusiness.industryMitomycin CGlaucomaMiddle Agedmedicine.diseaseCombined Modality Therapyeye diseasesScleraScleral DiseasesOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryFemalesense organsBleb (medicine)medicine.symptombusiness030217 neurology & neurosurgeryScleraJournal of glaucoma
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Refractive lens exchange with the Acri. Twin asymmetric diffractive bifocal intraocular lens system

2009

PURPOSE To evaluate efficacy, safety, and predictability after refractive lens exchange (RLE) in patients who had implantation of asymmetric Acri.Twin bifocal diffractive intraocular lenses. METHODS The study comprised 130 eyes of 65 consecutive patients after RLE who had bilateral implantation of the Acri.Twin system. Eyes were divided into myopic and hyperopic groups. Binocular uncorrected distance visual acuity, best-corrected distance visual acuity (BCVA), uncorrected distance near visual acuity, and best distance-corrected near visual acuity (BCNVA) were recorded preoperatively and 6 months after surgery. RESULTS Efficacy indexes were 0.99 for myopic and 0.93 for hyperopic patients at …

AdultMaleReoperationmedicine.medical_specialtyVisual acuityDistance visual acuitygenetic structuresmedicine.medical_treatmentVisual AcuityIntraocular lensRefractive lens exchangeFunctional Laterality03 medical and health sciences0302 clinical medicineLens Implantation IntraocularOphthalmologyMyopiamedicineHumansIn patientProspective StudiesAgedLenses IntraocularPhacoemulsificationbusiness.industryPresbyopiaGeneral MedicinePresbyopiaMiddle AgedMultifocal intraocular lensmedicine.diseaseeye diseasesOphthalmologyHyperopiaIntraocular lenses030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryEuropean Journal of Ophthalmology
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Comparison of short-term light disturbance, optical and visual performance outcomes between a myopia control contact lens and a single-vision contact…

2020

Purpose To compare the optical and visual performance of a dual-focus (DF) contact lens used for myopia control with a single-vision (SV) contact lens of the same material. Methods A randomised, double-masked crossover study. Twenty-eight healthy, myopic volunteers between 18 and 32 years of age (23.49 +/- 4.07 years) participated in this study. The sensory dominant eye for distance vision was determined. Refraction, best-corrected visual acuity (VA) and aberrations for 3 mm and 5 mm pupil diameters were quantified without a contact lens in situ. Subjects were fitted with two contact lens designs: DF and SV, both made of omafilcon A material. The Quality of Vision (QoV) questionnaire, over-…

AdultMaleTime FactorsAdolescentgenetic structuresVisual qualityControl (management)Visual AcuityVisual performanceLight disturbanceContrast Sensitivity03 medical and health sciencesYoung Adult0302 clinical medicineDouble-Blind MethodMyopiaHumansMiSightCross-Over StudiesScience & TechnologyColor VisionMultifocal contact lensContact Lenses HydrophilicSensory Systemseye diseasesTerm (time)Contact lensOphthalmologyScholarship030221 ophthalmology & optometryOptometryFemalePsychology030217 neurology & neurosurgeryMyopia controlOptometryFollow-Up Studies
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