Search results for "1117 Public Health And Health Services"

showing 10 items of 31 documents

Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from th…

2020

Incluye: Correction: Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017. Inj Prev. 2020 Oct;26(Supp 1):i164. doi: 10.1136/injuryprev-2019-043296corr1. Epub 2020 Sep 28. PMID: 32989004 Background: The epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjuste…

Epidemiologyburden of disease; descriptive epidemiology; epidemiologyECONOMIC-DEVELOPMENT1106 Human Movement and Sports SciencesPoison controlburden of diseaseGlobal HealthGlobal Burden of Disease0302 clinical medicineQuality-Adjusted Life YearGlobal health030212 general & internal medicine10. No inequality1. No povertyBurden of diseaseDALYS3142 Public health care science environmental and occupational healthddc:3. Good healthDescriptive epidemiologyEpidemiological transitionREGISTRATIONDisabled PersonepidemiologyPublic Healthdescriptive epidemiologyHumanmedicine.medical_specialtyDEATHSAdolescent1117 Public Health and Health Services03 medical and health sciencesLife ExpectancyInjury preventionSYSTEMATIC ANALYSISmedicineDisability-adjusted life yearDisease burdenEstimationburden of disease descriptive epidemiology epidemiologyMORTALITYPublic healthEPIDEMIOLOGIC TRANSITIONPublic Health Environmental and Occupational Health030208 emergency & critical care medicineTRENDSEXPECTANCY HALE1701 PsychologyWounds and InjuriesHuman medicineDemography
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An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs.

2021

[BACKGROUND & AIMS] Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intra-hepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating the search for novel therapies. Previous genome-wide association studies (GWAS) and meta-analyses (GWMA) of PBC have identified numerous risk loci for this condition, providing insight into its aetiology. We undertook the largest GWMA of PBC to date, aiming to identify additional risk loci and prioritise candidate genes for in silico drug efficacy screening. [METHODS] We combined new and existing genotype data for 10, 516 cases and 20, 77…

Liver CirrhosisALSPAC; ERN RARE-LIVER; Genomic co-localization; Network-based in silico drug efficacy screening; UK-PBC0301 basic medicineCandidate geneALSPAC; ERN RARE-LIVER; Genomic co-localization; Network-based in silico drug efficacy screening; UK-PBC; Genome-Wide Association Study; Humans; Liver Cirrhosis BiliaryItalian PBC Study GroupLD SCORE REGRESSIONJapan-PBC-GWAS ConsortiumGenome-wide association studyLocus (genetics)DiseaseSUSCEPTIBILITYPBCChronic liver diseaseBioinformaticsGENETIC ASSOCIATION1117 Public Health and Health Services03 medical and health sciences0302 clinical medicineUK-PBC ConsortiumGenotypeHumansMedicineNetwork-based in silico drug efficacy screeningGenetic associationScience & TechnologyGastroenterology & HepatologyHepatologyLiver Cirrhosis Biliarybusiness.industryBiliaryChinese PBC Consortium1103 Clinical SciencesALSPACmedicine.diseasePBC Consortia030104 developmental biologyMeta-analysisERN RARE LIVER030211 gastroenterology & hepatologyGenomic co-localizationUK-PBCUS PBC ConsortiumERN RARE-LIVERCanadian PBC ConsortiumbusinessLife Sciences & BiomedicineGenome-Wide Association StudyHuman
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Hospital readmission rates: signal of failure or success?

2013

AbstractHospital readmission rates are increasingly used as signals of hospital performance and a basis for hospital reimbursement. However, their interpretation may be complicated by differential patient survival rates. If patient characteristics are not perfectly observable and hospitals differ in their mortality rates, then hospitals with low mortality rates are likely to have a larger share of un-observably sicker patients at risk of a readmission. Their performance on readmissions will then be underestimated. We examine hospitals’ performance relaxing the assumption of independence between mortality and readmissions implicitly adopted in many empirical applications. We use data from th…

MaleMORTALITY-RATESEconomicsIMPACTSocial SciencesHospital performanceC50Business & EconomicsReadmission ratesmedia_commonAged 80 and overHip fractureOUTCOMESI18Mortality rateHealth PolicyHEALTH CARE SCIENCES & SERVICESHospitalsSurvival RateEngland1117 Public Health And Health ServicesMortality ratesFemaleMedical emergencyHEALTHLife Sciences & BiomedicineSample selectionmedicine.medical_specialtyACUTE MYOCARDIAL-INFARCTIONmedia_common.quotation_subjectBivariate analysisPatient ReadmissionReadmission ratemedicineQUALITYHumansSurvival rate1402 Applied EconomicsSelection (genetic algorithm)AgedQuality of Health CareSelection biasHospital readmissionSAMPLE SELECTIONScience & TechnologyModels Statisticalbusiness.industryHip FracturesPublic Health Environmental and Occupational HealthHIP FRACTUREHEALTH POLICY & SERVICESmedicine.diseaseMortality rateMODELEmergency medicinebusinessRACOSTS
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

2020

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347

MaleOriginalmedicine.medical_treatmentartificialCritical Care and Intensive Care MedicineMedical and Health SciencesPressure ulcerlaw.inventionDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factors; Adult; Aged; Hospital Mortality; Humans; Male; Patient Discharge; Prevalence; Risk Factors; Intensive Care Units; Respiration Artificial0302 clinical medicineDecubitus epidemiologydecubitus epidemiology ; ICU ; pressure injury ; pressure ulcer ; outcome ; risk factors ; morbidity ; mortalitylawMedicine and Health SciencesadultsPrevalenceMedicineHospital MortalitySimplified Acute Physiology Scoredecubitus epidemiology; icu; pressure injury; pressure ulcer; outcome; risk factors; morbidityziekenhuissterfteImmunodeficiencyintensive careOutcomeEuropean Society of Intensive Care Medicine (ESICM) Trials Group CollaboratorsmannenvolwassenenCOSTIntensive care unitSTATEPatient DischargeIntensive Care UnitsULCERSUnderweightmedicine.symptomLife Sciences & BiomedicineDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factorsHumanAdultmedicine.medical_specialtyrisicofactorenDecubitus epidemiology ICU Pressure injury Pressure ulcer Outcome Risk factors Morbidity Mortalitypressure injuriesIntensive Care UnitprevalentieNO1117 Public Health and Health ServicesDecubICUs Study Team03 medical and health sciencesCritical Care MedicineAnesthesiologyGeneral & Internal MedicineHealth SciencesouderenHumansMortalityAgedMechanical ventilationScience & Technologybusiness.industrydecubitusRisk Factor030208 emergency & critical care medicine1103 Clinical SciencesOdds ratiomedicine.diseaseRespiration ArtificialEmergency & Critical Care MedicineConfidence interval030228 respiratory systemRisk factorsEmergency medicineICUkunstmatige ademhalingRISK-FACTORSMorbiditybusinessPressure injuryrespiration
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Estimating global injuries morbidity and mortality

2020

Background. While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods. In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then est…

MalePopulations/contexts1106 Human Movement and Sports SciencesGlobal injuriespopulation030204 cardiovascular system & hematologyGlobal HealthcontextscontextGlobal Burden of Disease0302 clinical medicineQuality-Adjusted Life YearGlobal health1506030212 general & internal medicineOriginal ResearchDatapopulations/contextsIncidence (epidemiology)Incidencemethodology3142 Public health care science environmental and occupational healthPeer reviewFemalePublic HealthTERRITORIESQuality-Adjusted Life Yearsdescriptive epidemiologyHumanDisabilities195 COUNTRIESstatistical issue1117 Public Health and Health Services03 medical and health sciencesAGELife ExpectancyEnvironmental healthInjury preventionSYSTEMATIC ANALYSISstatistical issuesHumansMortalityEstimationSEX-SPECIFIC MORTALITYDISABILITYPublic Health Environmental and Occupational Healthpopulations; contexts; methodology; descriptive epidemiology; statistical issues; Female; Humans; Incidence; Life Expectancy; Male; Morbidity; Quality-Adjusted Life Years; Global Burden of Disease; Global Health; Wounds and Injuriespopulations1106 Human Movement and Sports Sciences 1117 Public Health and Health Services 1701 PsychologyQuality-adjusted life yearYears of potential life lost1701 PsychologyLife expectancyEstimatesWounds and InjuriesHuman medicineMorbiditypopulations/contextInjury prevention
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20…

2020

Artículo con numerosos autores. Sólo se hace referencia al primero que coincide con el de la UAM y al colectivo

MaleRespiratory diseasesRespiratory Tract DiseasesDiseaseChronic respiratory diseasesGlobal Burden of DiseasePulmonary Disease Chronic Obstructive0302 clinical medicineCost of Illness11. SustainabilityMETABOLIC RISKSEPIDEMIOLOGY030212 general & internal medicineChildCause of deathAged 80 and overCOPDDALYChronic obstructive pulmonary diseaseMortality rateRespiratory disease1. No povertyAge FactorsMiddle AgedDeath causes3. Good healthPREVALENCEHealth risksChild PreschoolCOMPARATIVE RISK-ASSESSMENTFemaledeath and disability worldwideQuality-Adjusted Life YearsTERRITORIESBURDENgrowth in absolute numbersPulmonary and Respiratory MedicineAdultADJUSTED LIFE-YEARSHealth burdensAdolescentMedicina195 COUNTRIESchronic respiratory diseasesArticle1117 Public Health and Health Services03 medical and health sciencesYoung AdultLife ExpectancySex FactorsBurden of Disease Respiratory diseaseSarcoidosis PulmonaryEnvironmental healthmedicineDisability-adjusted life yearHumansCOPDEXPOSURERisk factorMortalityAgedper-capita basisbusiness.industryDISABILITYInfant NewbornInfant1103 Clinical Sciencesasthmamedicine.diseaseAsthmaYears of potential life lost030228 respiratory systemRisk factors13. Climate actionSystematic analysesChronic DiseaseINJURIESHuman medicinePneumoconiosisMorbiditybusinessLung Diseases Interstitial1199 Other Medical and Health Sciences
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Fluid challenges in intensive care: the FENICE study: a global inception cohort study

2015

Background: Fluid challenges (FCs) are one of the most commonly used therapies in critically ill patients and represent the cornerstone of hemodynamic management in intensive care units. There are clear benefits and harms from fluid therapy. Limited data on the indication, type, amount and rate of an FC in critically ill patients exist in the literature. The primary aim was to evaluate how physicians conduct FCs in terms of type, volume, and rate of given fluid; the secondary aim was to evaluate variables used to trigger an FC and to compare the proportion of patients receiving further fluid administration based on the response to the FC. Methods: This was an observational study conducted i…

MaleSoins intensifs réanimationmedicine.medical_treatmentCohort Studies; Female; Humans; Male; Middle Aged; Practice Patterns Physicians'; Critical Care; Fluid Therapy; Critical Care and Intensive Care MedicinePractice PatternsESICM Trial GroupCritical Care and Intensive Care MedicineRESPONSIVENESSCohort StudiesSeven-Day Profile PublicationMedicine and Health SciencesPractice Patterns Physicians'FENICE InvestigatorsCIRCULATORY SHOCKintensive careddc:617RENAL REPLACEMENT THERAPYMiddle Aged3. Good healthOF-THE-LITERATURESHOCKFemalelipids (amino acids peptides and proteins)Erratumintensive care fluid therapyfluidsLife Sciences & BiomedicineCRITICALLY-ILL PATIENTSHumanCohort studymedicine.medical_specialtyCritical CareHYDROXYETHYL STARCH 130/0.4MEDLINE1117 Public Health and Health ServicesNOfluid therapyCritical Care MedicineCIRCULATORYGeneral & Internal MedicineIntensive careAnesthesiologyPATIENTSmedicinecohort studyHumansRenal replacement therapyIntensive care medicineintensive care; fluids; cohort studyPhysicians'Science & TechnologyCRITICALLY-ILLbusiness.industrySeptic shockSEPTIC SHOCK1103 Clinical Sciences3126 Surgery anesthesiology intensive care radiologymedicine.diseaseEmergency & Critical Care MedicineARTERIAL-PRESSURESEVERE SEPSISClinical trialFluid TherapyObservational studyCohort Studiebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyTASK-FORCE
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Alcohol-impaired Walking in 16 Countries: A Theory-Based Investigation.

2021

Alcohol is a global risk factor for road trauma. Although drink driving has received most of the scholarly attention, there is growing evidence of the risks of alcohol-impaired walking. Alcohol-impaired pedestrians are over-represented in fatal crashes compared to non-impaired pedestrians. Additionally, empirical evidence shows that alcohol intoxication impairs road-crossing judgements. Besides some limited early research, much is unknown about the global prevalence and determinants of alcohol-impaired walking. Understanding alcohol-impaired walking will support health promotion initiatives and injury prevention. The present investigation has three aims: (1) compare the prevalence of alcoho…

MaleTheory of planned behavioursubstance usePoison controlTheory of Planned BehaviourHuman Factors and ErgonomicsPedestrianIntentionWalkingSubstance useSuicide preventionOccupational safety and health03 medical and health sciences0302 clinical medicineRisk-TakingSurveys and Questionnaires0502 economics and businessInjury preventionHumansmulti-country study030212 general & internal medicineSafety Risk Reliability and QualityPedestrians050210 logistics & transportation05 social sciencesLogistics & TransportationPublic Health Environmental and Occupational HealthTheory of planned behaviorAccidents TrafficHuman factors and ergonomicsactive travelMulti-country studyActive travel3. Good healthRisk perception1117 Public Health and Health Services 1507 Transportation and Freight Services 1701 PsychologyCross-Sectional StudiesAlcoholPsychologyVulnerable road usershuman activitiesvulnerable road usersDemography
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Xenon Improves Neurologic Outcome and Reduces Secondary Injury Following Trauma in an In Vivo Model of Traumatic Brain Injury*

2014

Objectives: To determine the neuroprotective efficacy of the inert gas xenon following traumatic brain injury and to determine whether application of xenon has a clinically relevant therapeutic time window. Design: Controlled animal study. Setting: University research laboratory. Subjects: Male C57BL/6N mice (n = 196). Interventions: Seventy-five percent xenon, 50% xenon, or 30% xenon, with 25% oxygen (balance nitrogen) treatment following mechanical brain lesion by controlled cortical impact. Measurements and Main Results: Outcome following trauma was measured using 1) functional neurologic outcome score, 2) histological measurement of contusion volume, and 3) analysis of locomotor functio…

MaleXenonINTRACRANIAL-PRESSURE1110 NursingCritical Care and Intensive Care MedicineGAIT ABNORMALITIESXenonGaitIntracranial pressureintegumentary systemBrainGLYCINE SITEINTRACEREBRAL-HEMORRHAGED-ASPARTATE RECEPTORNeuroprotective AgentsTreatment OutcomeAnesthesiahead traumaneuroprotectionLife Sciences & BiomedicinePOTASSIUM CHANNELSLocomotioncirculatory and respiratory physiologyinorganic chemicalsTraumatic brain injurychemistry.chemical_elementNeuroprotection1117 Public Health and Health ServicesHead traumaCritical Care MedicineIn vivoGeneral & Internal MedicineAdministration InhalationmedicineAnimalscardiovascular diseasesIntracerebral hemorrhageScience & Technologybusiness.industry1103 Clinical Sciencesbrain injurymedicine.diseaseCONTROLLED CORTICAL IMPACTCOMPETITIVE-INHIBITIONEmergency & Critical Care MedicineMice Inbred C57BLDisease Models AnimalCOGNITIVE DEFICITSchemistryBrain InjuriesClosed head injurybusinessCLOSED-HEAD INJURYinert gasesCritical Care Medicine
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Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease …

2020

ObjectivesThis study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study.MethodsThe GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors.ResultsIn 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39…

Maleexposure assessmentGlobal Healthmedicine.disease_causeGlobal Burden of DiseaseergonomicGBD 2016 Occupational Risk Factors Collaborators0302 clinical medicineRisk Factors1599 Other Commerce Management Tourism and ServicesNeoplasmsMETABOLIC RISKSPer capitaMedicine1506030212 general & internal medicinePublic Environmental & Occupational HealthAged 80 and overeducation.field_of_studyHuman factors and ergonomicsMiddle Aged030210 environmental & occupational health3142 Public health care science environmental and occupational health3. Good healthOccupational DiseasesCOMPARATIVE RISK-ASSESSMENTFemaleQuality-Adjusted Life YearsRisk assessmentLife Sciences & BiomedicineAdultCOUNTRIESnoiseAdolescentPopulationcancer; ergonomic; noise; respiratory tract diseases; workplaceRisk AssessmentEnvironmental & Occupational HealthAsbestosrespiratory tract disease1117 Public Health and Health ServicesYoung Adult03 medical and health sciencesAge DistributionLife ExpectancyOccupational ExposureEnvironmental healthHumanscancerDisabled PersonsSex DistributioneducationAgedScience & Technologybusiness.industryPublic Health Environmental and Occupational Health1103 Clinical SciencesTRENDSQuality-adjusted life yearrespiratory tract diseasesworkplaceSocioeconomic FactorsAttributable riskCommentaryLife expectancyWounds and InjuriesCLUSTERSbusinessLow Back PainOccupational and Environmental Medicine
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