Search results for "12a"
showing 4 items of 44 documents
CCDC 635027: Experimental Crystal Structure Determination
2008
Related Article: A.Valkonen, E.Kolehmainen, M.Lahtinen, E.Sievanen, V.Noponen, M.Tolonen, R.Kauppinen|2007|Molecules|12|2161|doi:10.3390/12092161
CCDC 667968: Experimental Crystal Structure Determination
2009
Related Article: A.Valkonen, M.Lahtinen, E.Kolehmainen|2008|Steroids|73|1228|doi:10.1016/j.steroids.2008.06.006
CCDC 841799: Experimental Crystal Structure Determination
2012
Related Article: V.Noponen, H.Belt, M.Lahtinen, A.Valkonen, H.Salo, J.Ulrichova, A.Galandakova, E.Sievanen|2012|Steroids|77|193|doi:10.1016/j.steroids.2011.11.006
Gitelman syndrome DD thiazide diuretics abuse
2014
Abstract Introduction. Gitelman syndrome (GS) is a rare inherited disorder. Mutations in SLC12A3 gene that encode tubular Na+Cl-cotransporter (NCCT) cause hypokalemic metabolic alkalosis, salt loss, hypomagnesaemia and hypocalciuria. The symptoms include weakness, vertigo, hypotension, tetany, paresthesia and nausea. Diagnostic criteria are a normal urine concentrating ability, normal glomerular filtration rate (GFR), hypomagnesaemia (<0,65mmol/l), hypokalemia (<3,6mmol/l) and hypocalciuria (<0,1mmol/mmol creatinine). Previously, the diagnosis was made by exclusion. Today, genetic analysis can ensure diagnosis. Thiazide diuretics (TD) abuse with similar abnormalities can make the d…