Search results for "15"

Conocimiento, traza e ingenio en la arquitectura valenciana del siglo XV

2012

In the last decades historiography of gothic architecture in the Crown of Aragon has focused on buildings monographs, documentary research and technical change in stone building. On the other hand, historians of technology have given special attention to the issue of innovation and its diffusion in the late Middle Ages, considering building techniques as a particular field of research. This essay studies transmission of technical knowledge in building trades in order to explain architectural changes in an outstanding environment of innovation such as the kingdom of Valencia in the 14th and 15th centuries, especially from 1430 onwards. Having account of previous research and some cases of st…

On time-harmonic Maxwell equations with nonhomogeneous conductivities : Solvability and FE-approximation

1989

The solvability of time-harmonic Maxwell equations in the 3D-case with non­homogeneous conductivities is considered by adapting Sobolev space technique and variational formulation of the probJem in question. Moreover, a finite element approximation is presented in the 3D·case together with an error estimate in the energy norm. Some remarks are given to the 2D-problem arising from geophysics. peerReviewed

Shape optimization in contact problems based on penalization of the state inequality

1986

The paper deals with the approximation of optimal shape of elastic bodies, uni­laterally supported by a rigid, frictionless foundation. Original state inequality, describing the behaviour of such a body is replaced by a family of penalized state problems. The relation between optimal shapes for the original state inequality and those for penalized state equations is established. peerReviewed

Freedom, Civility and Activeness. On the government of leisure self-formation of Finnish multicultural youth

2012

This article explores the leisure time and civic activities of ‘multicultural youth’ in Finland. The theoretic-conceptual framework is the Foucauldian governmentality approach and Foucault's four step model of the ethical self-formation of the moral subject. This toolkit exposes how the subjectivation of the multicultural youth takes place in their leisure time activities and civic action, and connects and disconnects with the desires and expectations of administration and youth workers. The leisure time subjectivation of the youth implements on the interface of their own ‘self-driven’ activities and interests and more or less programmatic governance of official youth work with its integrat…

Multilevel Latent Profile Analysis With Covariates : Identifying Job Characteristics Profiles in Hierarchical Data as an Example

2018

Latent profile analysis (LPA) is a person-centered method commonly used in organizational research to identify homogeneous subpopulations of employees within a heterogeneous population. However, in the case of nested data structures, such as employees nested in work departments, multilevel techniques are needed. Multilevel LPA (MLPA) enables adequate modeling of subpopulations in hierarchical data sets. MLPA enables investigation of variability in the proportions of Level 1 profiles across Level 2 units, and of Level 2 latent classes based on the proportions of Level 1 latent profiles and Level 1 ratings, and the extent to which covariates drawn from the different hierarchical levels of th…

A person-oriented approach to diary data. Children’s temperamental negative emotionality increases susceptibility to emotion transmission in father-c…

2015

The notion that some individuals are more prone to emotion transmission than others has prompted the need for a person-oriented approach to emotion transmission in parent-child dyads. The present study applied a person-oriented analysis to examine the patterns of emotion transmission that can be identified in the diary data of father-child dyads, and the extent to which children with high levels of temperamental negative emotionality are particularly susceptible to emotion transmission within the family. Mothers of 149 first grade children (age 6 to 7) completed questionnaires concerning their child’s temperament. Mothers and fathers maintained diary questionnaires (for a total of 7 days) c…

Network meta-analysis of randomized trials in multiple myeloma: Efficacy and safety in frontline therapy for patients not eligible for transplant

2022

The treatment scenario for newly-diagnosed transplant-ineligible multiple myeloma patients (NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors (PI) and/or immunomodulatory drugs (IMiD) +/- the monoclonal antibody Daratumumab are used for first-line treatment, even if head-to-head comparisons are lacking. To compare efficacy and safety of these regimens, we performed a network meta-analysis (NMA) of 27 phase 2/3 randomized trials including a total of 12935 patients and 23 different schedules. Four efficacy/outcome and one safety indicators were extracted and integrated to obtain (for each treatment) the surface under the cumulative ranking-curve (SUCRA), a metric use…

ABSOLUTE LYMPHOCYTE COUNT AS PREDICTOR FOR SURVIVAL IN NEWLY DIAGNOSED ELDERLY PATIENTS WITH MULTIPLE MYELOMA

2011

ABSOLUTE LYMPHOCYTE COUNT IS NOT A PREDICTOR FOR SURVIVAL IN NEWLY DIAGNOSED ELDERLY PATIENTS WITH MULTIPLE MYELOMA. FINAL RESULTS OF A MULTICENTER S…

2012

1H NMR-Based Metabolomics to Assess the Impact of Soil Type on the Chemical Composition of Nero d’Avola Red Wines

2023

: In this study, the soil effect on the micro-component composition of Nero d'Avola wines obtained from different locations was investigated through 1H NMR-based metabolomics. Two different approaches were applied: the targeted (TA) and the non-targeted one (NTA). The former differentiated the wines by profiling (i.e., by identifying and quantifying) a number of different metabolites. The latter provided wine fingerprinting by processing the entire spectra with multivariate statistical analysis. NTA also allowed investigation of the hydrogen bond network inside wines via the analysis of 1H NMR chemical shift dispersions. Results showed that the differences among wines were due not only to t…